Genetic News and Research

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New diabetes form found by Norwegian researchers

A research group in Bergen has discovered a new form of diabetes. In addition to high blood sugar levels, the disease is characterised by a decrease in pancreatic functioning and reduced fat absorption in the intestine. The discovery may have an impact on the treatment of more usual forms of diabetes.

6 Jan 2006

Soy diet worsens heart disease in mice

Researchers from the University of Colorado have shown that mice carrying a genetic mutation that is linked to altered heart growth and function in humans, have significantly worse heart problems if fed a soy diet, when compared to mice fed a soy-free (milk protein-based) diet.

6 Jan 2006

New model for the origin of rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the most common systemic autoimmune diseases, and one of the least understood. Smoking is the major known environmental risk factor for RA, though little is known about the mechanisms involved.

6 Jan 2006

Researchers discover that large segments of human genome are devoid of mobile DNA elements called transposons

Scientists from the University of Queensland, Australia report in the journal Genome Research that large segments of the human genome are conspicuously devoid of ubiquitous mobile DNA elements called transposons.

6 Jan 2006

Prospect of personalized medicine places new demands on the evaluation of new medicines

As we enter the era of personalized medicine, it is time to take a fresh look at how we evaluate new medicines and treatments for cancer, according to Donald Berry, Ph.D., professor and chair of the Department of Biostatistics and Applied Mathematics at The University of Texas M. D. Anderson Cancer Center.

6 Jan 2006

Caspase 8 gene halts spread of aggressive childhood cancer

A team of cancer researchers has shown that a gene commonly lost during neuroblastoma tumor formation, one of the most aggressive cancers in babies and children, is in fact a "metastasis suppressor" gene.

6 Jan 2006

Australian researchers discover stem cell that drives the formation of all breast tissue

Victorian Breast Cancer Research Consortium scientists from The Walter and Eliza Hall Institute, using a mouse model, have discovered the rare stem cell that drives the formation of all breast tissue.

5 Jan 2006

Researchers move closer to understanding the basis of a severe epilepsy and mental retardation

Researchers at the University of California, San Diego (UCSD) School of Medicine took a step closer to understanding the basis of a severe epilepsy and mental retardation syndrome with work published in the January 5, 2006 issue of the journal Neuron.

5 Jan 2006

Pharmacogenetics can reduce health care costs

Chances are good that a medication you take is one of several drugs that can be affected by genetic factors, according to researchers at Washington University School of Medicine in St. Louis and the St. Louis College of Pharmacy.

5 Jan 2006

Surprise discovery helps tackle rabies

In an unexpected discovery, scientists at Jefferson Medical College have found that a tiny change in a rabies virus protein can turn a "safe" virus extremely deadly. The finding has enabled the researchers to refine a vaccine they previously created against rabies in wildlife, making it safer and more effective.

5 Jan 2006

Genetic risk factors for depression greater in women

Virginia Commonwealth University researchers have found that genes contribute more strongly to the risk of depression in women than in men, and that there may be some genetic factors that are operating uniquely in one sex and not in the other.

5 Jan 2006

UCLA examines disease-versus-disease interactions

The knowledge that one disease may prevent the onset of another is not new. For example, the discovery that cowpox vaccines can prevent smallpox dates back to 1798.

5 Jan 2006

New hope for osteoporosis sufferers

Medical researchers at the University of Bonn, working in collaboration with scientists from Israel, the USA and Britain, have identified a previously unknown regulatory mechanism in the process of bone loss. Their findings could open up new approaches to the treatment of osteoporosis.

4 Jan 2006

Smokers with a family history of lung cancer encouraged to undergo screening

To detect invasive lung cancer in its early stages, researchers urge current and former smokers who have a strong family history of the disease to take a lung function test and undergo screening with spiral computed tomography. The test is especially important should the previously diagnosed relative be young (around 50).

2 Jan 2006

New human embryonic stem cells grown in animal cell-free cultures

Scientists working at the WiCell Research Institute, a private laboratory affiliated with the University of Wisconsin-Madison, have developed a precisely defined stem cell culture system free of animal cells and used it to derived two new human embryonic stem cell.

2 Jan 2006

Identification of regulatory mechanism could lead to new treatments of osteoporosis

2 Jan 2006

Breakdown of myelin linked to genetic risk of Alzheimer's disease

A new UCLA imaging study shows that age-related breakdown of myelin, the fatty insulation coating the brain's internal wiring, correlates strongly with the presence of a key genetic risk factor for Alzheimer disease.

2 Jan 2006

Brain volume may be used as an early detection system for dementia

Reduced volume, or atrophy, in parts of the brain known as the amygdala and hippocampus may predict which cognitively healthy elderly people will develop dementia over a six-year period, according to a study in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Jan 2006

Eating disorders linked to perinatal complications

Certain complications during and immediately after birth are associated with the development of the eating disorders anorexia nervosa and bulimia nervosa, according to a study in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Jan 2006

Researchers discover how a gene linked to Parkinson’s disease can keep brain cells alive

Researchers at the University of Colorado at Denver and Health Sciences Center’s School of Medicine have uncovered how a gene linked to Parkinson’s disease can keep brain cells alive. The results suggest the possibility for new drugs that might regulate the gene and protect Parkinson’s patients from further cell damage.

29 Dec 2005