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New gene therapy maybe useful for treating muscular dystrophy

A new gene therapy technique that has shown promise in skin disease and hemophilia might one day be useful for treating muscular dystrophy, according to a new study by researchers at Stanford University School of Medicine.

29 Dec 2005

World's deadliest malaria parasite cloaking gene revealed

The world's deadliest malaria parasite, Plasmodium falciparum, sneaks past the human immune system with the help of a wardrobe of invisibility cloaks. If a person's immune cells learn to recognize one of the parasite's many camouflage proteins, the surviving invaders can swap disguises and slip away again to cause more damage. Malaria kills an estimated 2.7 million people annually worldwide, 75 percent of them children in Africa.

29 Dec 2005

New drug shows promise in fighting Tuberculosis (TB)

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have determined how a promising drug candidate attacks the bacterium that causes tuberculosis (TB). Published online this week in Proceedings of the National Academy of Sciences, the finding may help scientists optimize the drug candidate, PA-824, which targets Mycobacterium tuberculosis (M. tb).

28 Dec 2005

New drug shows promise in fighting Tuberculosis (TB)

28 Dec 2005

Heart disease risk higher if a brother or sister has heart problems

According to a new report having a brother or sister with a cardiovascular disease poses a greater risk than having a parent with a history of the disease.

28 Dec 2005

Bigger brain = more intellectual capacity

Brain size matters for intellectual ability and bigger is better, McMaster University researchers have found.

22 Dec 2005

Gene discovery may prevent craniofacial birth defects

Craniofacial researchers have developed an animal model that explains how skull malformations occur and how they might be prevented.

22 Dec 2005

Plant stem cell breakthrough made

Totipotent stem cells allow plants to build new organs throughout their whole life. But it has been unclear how hormones and genetic factors work together to prevent plants from having growth that is either stunted, or uncontrolled and tumor-like. Scientists from the Max Planck Institute for Developmental Biology have now uncovered a feedback mechanism, involving a growth-enhancing hormone and a regulatory protein, which controls the number of stem cells the plant produces.

22 Dec 2005

Women suffering lupus OK to take oral contraceptives

Major study of women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

22 Dec 2005

Chromosome link found between alcohol addiction and smoking

Scientists have found in a study of tobacco users that their drinking behavior is linked to some of the same chromosome regions associated with alcohol addiction.

22 Dec 2005

Discovery reveals how malaria infects humans

Researchers at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in India and a unit of the European Molecular Biology Laboratory (EMBL) in France have made a key discovery about a molecule that helps the malaria parasite infect human cells.

22 Dec 2005

Genome discovery may prevent leukaemia

An international consortium has cracked the gene code behind a key family of fungi, which includes both the leading cause of death in leukaemia and bone marrow transplant patients and an essential ingredient of soy sauce.

From The University of Manchester 22 Dec 2005

2 million people carry drug-resistant bacteria in their noses

New research estimates that about 2 million people carry a strain of drug-resistant bacteria in their noses.

21 Dec 2005

Aquaporin related to obesity

Dr. Gema Fruhbeck, director of the Metabolic Research Laboratory of the University Hospital of the University of Navarra, has published a commentary in the latest issue of Nature. The article presents aquaporin as a new modulator of the biology of the adipocyte.

21 Dec 2005

Skin colour controlled by key gene

It seems that the genes of Zebrafish have much in common with humans' and scientists believe that studying the fish may help solve the mystery of human skin colour.

19 Dec 2005

Common gene variation lessens Tamoxifen’s benefit

Researchers have discovered that one of the most commonly prescribed drugs for breast cancer, tamoxifen, may not be as effective for women who inherit a common genetic variation.

19 Dec 2005

Robotic microbial protein analysis

Microorganisms have potential as living factories for manufacturing drugs and biochemical products. Rapid mass screening methods are needed to identify new species. A new robotic system also provides useful data for genetic engineering.

15 Dec 2005

The role of genes in the development of non-Hodgkin's lymphomas

An international consortium of epidemilogists - including Dr. Alexandra Nieters and Professor Nikolaus Becker of the Clinical Epidemiology Division of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) - has conducted the first ever investigation of genetic factors in the development of non-Hodgkin’s lymphoma (NHL) in a study called InterLymph.

15 Dec 2005

University at Buffalo researches rules for targeting RNA

Once described as DNA's less-famous chemical cousin, RNA, or ribonucleic acid, recently has moved to center stage.

15 Dec 2005

Gene therapy tackles hereditary spastic paraplegia

Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic paraplegia (HSP).

15 Dec 2005