Genetic News and Research

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Data supports use of personal and family history of breast cancer, ovarian cancer, or both in making clinical decisions

African American women at high-risk of breast cancer have genetic mutations that would make genetic testing feasible, according to a study in the October 19 issue of JAMA: The Journal of the American Medical Association.

18 Oct 2005

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

The humble yeast has revealed the molecular workings of an anti-cancer drug that stops the growth and spread of tumours in humans by starving their blood supply.

18 Oct 2005

Intensity modulated radiation therapy (IMRT) for head and neck cancer

Results from a University of Pittsburgh study evaluating intensity modulated radiation therapy (IMRT) for head and neck cancer determined the ideal doses for lessening treatment side effects. The findings were presented today at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Denver.

18 Oct 2005

People who carry a mutation in the melanoma susceptibility gene CDKN2A have a much lower risk of melanoma

In addition, most familial clusters of melanoma occur in families without identifiable mutations in this gene, according to a new study that appears in the October 19 issue of the Journal of the National Cancer Institute.

18 Oct 2005

Cutting-edge research to develop this range of next-generation biomedical devices

Revolutionary new self-diagnostic devices to provide early warning of deadly and debilitating illnesses like cancer, diabetes and heart disease are the aim of a Euro 22.5m Science Foundation Ireland research facility to be established at Dublin City University.

18 Oct 2005

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

By using a chemical analysis method developed for air-pollution testing, UCI chemists and pediatricians have found that people with cystic fibrosis exhale higher concentrations of sulfur compounds from their lungs than do people who don't have the disease.

17 Oct 2005

New genetic discovery may help explain why some people develop high blood pressure and others don't

It also gives new insight into how the kidneys govern the balance of salt in the body, a crucial task for regulating blood pressure. And, it reveals how a gene already linked to behavior and mental health can play a role in the body, as well as the brain.

17 Oct 2005

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

New treatment for the pediatric eye cancer retinoblastoma

Investigators at St. Jude Children's Research Hospital have demonstrated in laboratory studies a new treatment for the pediatric eye cancer retinoblastoma that appears to be more effective than the current standard therapy, and more likely to prevent the recurrence of this cancer. A report on their work appears in the October 15 issue of Clinical Cancer Research.

17 Oct 2005

New findings on brain tumors called ependymomas

Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children's Research Hospital. The discovery explains why some identical-looking ependymomas are actually distinctly different diseases, the researchers said.

17 Oct 2005

Tourette syndrome linked to SLITRK1 gene

Tourette syndrome is a distressing condition which affects one in every 100 people.

17 Oct 2005

Research reveals concerns over use of health information

New Economic & Social Research Council (ESRC) funded research has discovered that eight per cent of people are asked to pay a higher premium because of health 'ratings' - twice as many as previously thought.

16 Oct 2005

Ethnic differences in cardiovascular risk factors

Heredity plays a major role in determining the blood lipid profile and heart rate variability of blacks and whites, two major risk factors for coronary artery disease, researchers say.

16 Oct 2005

Possible explanation for the higher incidence of lung cancer in African Americans

Faulty cell cycle "checkpoints" that fail to respond to DNA damage effectively may contribute to the high incidence of lung cancer in African-Americans, say researchers at Georgetown University's Lombardi Comprehensive Cancer Center and the National Cancer Institute (NCI).

16 Oct 2005

Alternative methods to create stem cells successful in mice-studies

According to researchers in the U.S. two alternative methods for making embryonic stem cells, work in mice and could lead to a less controversial way to grow them.

16 Oct 2005

Remicade can improve psoriasis symptoms

An international team led by a dermatologist at The University of Manchester has found that treatment with the emerging drug infliximab, marketed as Remicade, can quickly and significantly improve psoriasis symptoms.

From The University of Manchester 13 Oct 2005

New public survey on stem cells

Stem cells are unique among human cells in that they possess the uncanny ability to develop into virtually any other cell of the body, offering a hypothetical tool kit for repairing diseased hearts, mending broken spinal cords, or correcting genetic diseases, among other hoped-for benefits.

13 Oct 2005

Discovery of agent that can suppress cancer development

In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development.

13 Oct 2005

PCBs found widely in the environment and absorbed in the diet - may damage sperm

Research by an European Union-supported international team of scientists has shown that polychlorinated biphenyls (PCBs) - synthetic organic chemicals found widely in the environment and absorbed in the diet - may damage sperm.

13 Oct 2005

First gene mutation associated with Tourette syndrome

Researchers have identified the first gene mutation associated with Tourette syndrome - opening a new avenue for understanding the complex disorder that causes muscle and vocal tics.

13 Oct 2005

Genetic News and Research

Data supports use of personal and family history of breast cancer, ovarian cancer, or both in making clinical decisions

Yeast cells help show how GSAO (glutathionarsenoxide) angiogenesis inhibitor drug works

Intensity modulated radiation therapy (IMRT) for head and neck cancer

People who carry a mutation in the melanoma susceptibility gene CDKN2A have a much lower risk of melanoma

Cutting-edge research to develop this range of next-generation biomedical devices

Breath-analysis testing may prove to be an effective method for detecting the damaging lung-bacteria growth seen in cystic fibrosis

New genetic discovery may help explain why some people develop high blood pressure and others don't

Significant step forward in the genome era

New treatment for the pediatric eye cancer retinoblastoma

New findings on brain tumors called ependymomas

Tourette syndrome linked to SLITRK1 gene

Research reveals concerns over use of health information

Ethnic differences in cardiovascular risk factors

Possible explanation for the higher incidence of lung cancer in African Americans

Alternative methods to create stem cells successful in mice-studies

Remicade can improve psoriasis symptoms

New public survey on stem cells

Discovery of agent that can suppress cancer development

PCBs found widely in the environment and absorbed in the diet - may damage sperm

First gene mutation associated with Tourette syndrome

Sequencing & Genomics: Elevating Science and Healthcare eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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