Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Diabetes drug liraglutide ineffective in patients with advanced heart failure

In an attempt to correct defects in the energy generation that contributes to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure. Despite improvements in blood sugar control, the therapy did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure.

9 Nov 2015

Weight-loss surgery may be safe for managing type 2 diabetes in patients with mild obesity

Weight-loss surgery, long considered a treatment largely reserved for people with severe obesity, may also be a good and safe option for the treatment of uncontrolled type 2 diabetes in those who are overweight or have mild to moderate obesity, according to researchers from Cleveland Clinic in Ohio.

6 Nov 2015

Sleep loss reduces insulin sensitivity, increases diabetes risk

A new study by the University of Colorado shows that the longer people are awake during the time their biological clock is telling them to sleep the worse their sensitivity to insulin, which is a precursor to diabetes.

6 Nov 2015

Higher insulin levels linked to worse prognosis in advanced breast cancer

Patients with breast cancer that has spread to other parts of the body (metastasised) and who have higher insulin levels than normal, but are not diabetic, have a significantly worse prognosis compared with those with normal insulin levels, a researcher will tell the Advanced Breast Cancer Third International Consensus Conference tomorrow (Friday).

5 Nov 2015

One night of sleep deficiency and six months on high-fat diet could both impair insulin sensitivity

New research finds that one night of sleep deprivation and six months on a high-fat diet could both impair insulin sensitivity to a similar degree, demonstrating the importance of a good night's sleep on health.

5 Nov 2015

Researchers explore effects of hypoglycemia on cardiovascular autonomic control

Past studies have shown an association between strict control of blood sugar and increased mortality. These studies have also suggested that a consequence of this strict control is low blood sugar (called hypoglycemia), which may have adverse effects on the heart.

3 Nov 2015

Study: Visceral fat in early pregnancy can increase risk of gestational diabetes

Women who have high levels of abdominal fat during their first trimester of pregnancy have a higher risk of developing diabetes later in their pregnancy, according to a new study published today in Diabetes Care.

3 Nov 2015

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

"This 'rotation model', which made the cover of BioEssays, represents a true paradigm shift in the membrane receptor field," stated Prof. Pierre De Meyts, a renowned researcher of insulin and receptor binding for almost half a century and one of the reviewers of the paper by Prof. Ichiro Maruyama, the head of the Information Processing Biology Unit at Okinawa Institute of Science and Technology Graduate University.

31 Oct 2015

Obese women who lose weight during pregnancy have healthier babies, save health care costs

A recent study conducted by The University of Texas Medical Branch at Galveston shows that severely obese women who maintained or lost weight during pregnancy had healthier babies and lower health care costs.

31 Oct 2015

New campaign raises awareness of City of Hope's life-saving mission and impact

Imagine being diagnosed with one of the most rare and aggressive forms of breast cancer, given a five percent chance to live and told having children will never be an option. Southern California local Kommah McDowell was told just that— and then she went to City of Hope.

31 Oct 2015

Discovery may allow physicians to warn patients years before onset of diabetes

A panel of markers have been discovered that helps identify if a person is pre-diabetic by measuring the fatty acids in their blood. This discovery by University of Hawai'i Cancer Center researchers may allow physicians to warn patients years before the onset of diabetes, therefore allowing them to change their lifestyle patterns potentially avoiding the diagnosis of a chronic disease.

30 Oct 2015

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

A research team led by UC San Francisco scientists has identified a molecular switch capable of converting unhealthy white fat into healthy, energy-burning brown fat in mice. Drugs that flip this switch rapidly reduced obesity and diabetes risk factors in mice fed a high fat diet.

30 Oct 2015

Tandem Diabetes Care sales grow 16% to $15.7 million in third quarter 2015

Tandem Diabetes Care, Inc., a medical device company and manufacturer of the t:slim, t:flex and t:slim G4 Insulin Pumps, today reported its financial results for the quarter ended September 30, 2015.

30 Oct 2015

UAB expert suggests three options to help kids with diabetes enjoy Halloween sweets

While ghosts, ghouls and goblins are suiting up for the yearly pilgrimage through neighborhoods in search of sweet treats synonymous with Halloween, candy-centric holidays pose challenging questions for parents of children with diabetes.

29 Oct 2015

New generation of incretin-based medicines allows coordinated action against diabesity

The new generation of incretin-based medicines will allow a coordinated action against the combination diabetes/obesity, also known as diabesity, in some cases with only a single weekly dose, and with the likelihood of additional beneficial effects on other health complications related to this condition, such as cardiovascular and neurodegenerative diseases.

28 Oct 2015

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. This work is being presented Oct. 27 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

28 Oct 2015

Pharmacy-led glycemic control program improves outcomes for surgical patients with diabetes

A pharmacy-led glycemic control program is linked to improved outcomes for surgical patients with diabetes and those who develop stress-induced hyperglycemia or high blood sugars as a result of surgery, according to a new Kaiser Permanente study published in the American Journal of Pharmacy Benefits.

28 Oct 2015

Insulin plays a much stronger role in regulating release of dopamine

Insulin, the hormone essential to all mammals for controlling blood sugar levels and a feeling of being full after eating, plays a much stronger role than previously known in regulating release of dopamine, a neurotransmitter that helps control the brain's reward and pleasure centers, new studies by researchers at NYU Langone Medical Center show.

27 Oct 2015

Production of insulin determines success rate of weight loss surgery

Danish researchers have found that the ability to produce insulin is pivotal to the success of weight loss surgery in patients with type 2-diabetes. The study provides a better point of departure for advise and determining which patients will benefit from surgery.

27 Oct 2015

Reducing sugar intake reverses chronic metabolic diseases in children

Reducing consumption of added sugar, even without reducing calories or losing weight, has the power to reverse a cluster of chronic metabolic diseases, including high cholesterol and blood pressure, in children in as little as 10 days, according to a study by researchers at UC San Francisco and Touro University California.

27 Oct 2015

Insulin News and Research

Further Reading

Diabetes drug liraglutide ineffective in patients with advanced heart failure

Weight-loss surgery may be safe for managing type 2 diabetes in patients with mild obesity

Sleep loss reduces insulin sensitivity, increases diabetes risk

Higher insulin levels linked to worse prognosis in advanced breast cancer

One night of sleep deficiency and six months on high-fat diet could both impair insulin sensitivity

Researchers explore effects of hypoglycemia on cardiovascular autonomic control

Study: Visceral fat in early pregnancy can increase risk of gestational diabetes

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

Obese women who lose weight during pregnancy have healthier babies, save health care costs

New campaign raises awareness of City of Hope's life-saving mission and impact

Discovery may allow physicians to warn patients years before onset of diabetes

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

Tandem Diabetes Care sales grow 16% to $15.7 million in third quarter 2015

UAB expert suggests three options to help kids with diabetes enjoy Halloween sweets

New generation of incretin-based medicines allows coordinated action against diabesity

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

Pharmacy-led glycemic control program improves outcomes for surgical patients with diabetes

Insulin plays a much stronger role in regulating release of dopamine

Production of insulin determines success rate of weight loss surgery

Reducing sugar intake reverses chronic metabolic diseases in children

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