Genetic News and Research

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Oral liquid Hydroxyurea promising for long-term use in babies with sickle cell disease

Treating babies who have sickle cell disease (SCD) with oral liquid hydroxyurea appears to prevent the onset of long-term complications triggered by this disease, according to results of a preliminary study by investigators at St. Jude Children's Research Hospital.

15 Jun 2005

Report on Hispanics and genes, culture, and medicines highlights the rise of individualized medicine

"The FDA's review today of BiDil could make it the first drug approved specifically for African Americans and marks the end of 'one-size-fits-all' medicine," said Dr. Jane L. Delgado, President and CEO of the National Alliance for Hispanic Health (the Alliance), the nation's leading Hispanic health advocacy group.

15 Jun 2005

New genetic test may detect risk of malignant hyperthermia (MH) from anesthesia

A rare but potentially life-threatening inherited condition called malignant hyperthermia (MH) may strike surgical patients who receive common drugs for general anesthesia.

14 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

New genetic test may detect risk of rare complication from anesthesia

A rare but potentially life- threatening inherited condition called malignant hyperthermia (MH) may strike surgical patients who receive common drugs for general anesthesia.

14 Jun 2005

New technology developed at Cornell University could make it just as easy to identify genes

A supermarket checkout computer can identify thousands of different items by scanning the tiny barcode printed on the package. New technology developed at Cornell University could make it just as easy to identify genes, pathogens, illegal drugs and other chemicals of interest by tagging them with color-coded probes made out of synthetic tree-shaped DNA.

14 Jun 2005

Research accelerates the search for an effective cancer vaccine

By devising a novel way to package the genome of a common human tumor virus - the virus that causes common warts, genital warts and that is implicated in prevalent cancers - scientists have paved the way for making the pathogen far more accessible to biomedical science.

13 Jun 2005

Women in the UK most anxious about breast cancer

A new survey has found that one in three British women would be willing to have both breasts removed if they thought they were at high risk of breast cancer.

13 Jun 2005

Researchers discover how microRNA are involved in the development of heart muscle

Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle.

12 Jun 2005

Bio-engineered skin provides clues to melanoma development

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine.

12 Jun 2005

Genetic variations predispose Mexican Americans to insulin resistance

Although numerous studies have shown that low-grade inflammation is linked to heart disease and diabetes, more recent studies have shown that inflammation plays a role in insulin resistance, a syndrome that leads to diabetes and heart disease and affects about one in four adults in the United States.

12 Jun 2005

Link between PKC enzyme and kidney disease in diabetes confirmed

Researchers at Joslin Diabetes Center have investigated PKC-beta - a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes - for more than two decades.

12 Jun 2005

Venom of marine cone snails may provide an improved treatment for neuropathic pain associated with diabetes

A cone snail toxin discovered by Melbourne researchers has proven to have great potential for easing pain and could provide an improved treatment for neuropathic pain associated with diabetes.

12 Jun 2005

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Scientists at Joslin Diabetes Center have investigated PKC-beta -- a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes -- for more than two decades.

10 Jun 2005

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

The basics of cell division are the same in both, but there's a heck of a lot more going on in immune cells, Johns Hopkins scientists have discovered.

10 Jun 2005

First clues as to why stem cells ignore stop signs in the cell cycle

Everyone knows that stem cells are controversial. Many people know that stem cells can grow into virtually any cell type found in the body, from a red blood cell to a muscle cell to a brain cell. But no one really knows why stem cells continue to divide and renew themselves long after the point where other cells stop dividing.

10 Jun 2005

DNA discovery may help explain disorders such as autism

Researchers have made a discovery that may in future help to explain many aspects of human social behavior and disorders such as autism.

10 Jun 2005

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Researchers at Johns Hopkins have uncovered how a majority of the genetic changes in the hepatic-C virus, the most common cause of liver disease, allow it to evade the body's immune system during infection.

10 Jun 2005

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

The finding, reported in the June 9 issue of Science Express, will allow scientists to study every stage of the HCV life cycle and develop drugs to treat this life-threatening disease that affects more than 170 million people around the world.

9 Jun 2005

Variations in genetic code affect social behavior

Why are some people shy while others are outgoing? A study in the current issue of Science demonstrates for the first time that social behavior may be shaped by differences in the length of seemingly non-functional DNA, sometimes referred to as junk DNA.

9 Jun 2005

Genetic News and Research

Oral liquid Hydroxyurea promising for long-term use in babies with sickle cell disease

Report on Hispanics and genes, culture, and medicines highlights the rise of individualized medicine

New genetic test may detect risk of malignant hyperthermia (MH) from anesthesia

Two common gene variations are associated with the risk for developing chronic kidney disease

New genetic test may detect risk of rare complication from anesthesia

New technology developed at Cornell University could make it just as easy to identify genes

Research accelerates the search for an effective cancer vaccine

Women in the UK most anxious about breast cancer

Researchers discover how microRNA are involved in the development of heart muscle

Bio-engineered skin provides clues to melanoma development

Genetic variations predispose Mexican Americans to insulin resistance

Link between PKC enzyme and kidney disease in diabetes confirmed

Venom of marine cone snails may provide an improved treatment for neuropathic pain associated with diabetes

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix

First clues as to why stem cells ignore stop signs in the cell cycle

DNA discovery may help explain disorders such as autism

Researchers discover how hepatic-C virus evades immune system in acute and chronic infections

Scientists produce for the first time an infectious form of the hepatitis C virus in laboratory cultures of human cells

Variations in genetic code affect social behavior

Sequencing & Genomics: Elevating Science and Healthcare eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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