Genetic News and Research

RSS

Accumulation of genetic changes is not solely determined by natural selection

New data suggest that the accumulation of genetic changes is not solely determined by natural selection. A study by University of Chicago researchers contradicts conventional theory by showing that the percentage of mutations accepted in evolution is also strongly swayed by the speed at which new mutations arrive at a gene: the faster the speed of new mutations, the greater the percentage of those mutations accepted.

9 Jun 2005

Exposing SMA-affected cells to aminoglycoside drugs can increase SMN

MDA grantee Christian Lorson at the University of Missouri was on a team that found that exposing cells carrying a mutation that causes spinal muscular atrophy (SMA) to drugs in the aminoglycoside family helps them produce more of the needed SMN protein, a lack of which leads to SMA.

9 Jun 2005

Research opens up new directions for studying prion diseases in humans

The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.

9 Jun 2005

MicroRNAs play an important role in human cancer

Over the past few years, scientists have discovered that a new class of genetic regulators called "microRNAs" influences normal human growth and development. Now, researchers have found that microRNAs also play an important role in human cancer. The findings are published in today's issue of the journal Nature (June 9).

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

Researchers link aberrant 'microRNA' expression to human cancer

8 Jun 2005

Several minute intermediate stage in virus-cell fusion may represent a window of opportunity for drug development

To ignite a life-threatening infection in the body, a virus such as HIV invades body cells by first merging, or fusing, with the cell's outer membrane. Once inside the cell, the invading microbe's genetic material takes over, turning the 'host' cell into a factory to produce more copies of the virus, which then spill out to invade other cells in the body.

8 Jun 2005

New understanding of microRNAs

Ribonucleic acid, or RNA, has long been thought to be important only to translate a gene's DNA into the proteins that are cells' workhorses. But new evidence shows that tiny bits of RNA not used to make proteins actually play central roles in normal biology and in the development of cancers.

8 Jun 2005

Missing link between mothers' diets and obesity in kids

New work may have found the missing link between mothers' diets and obesity in kids. A study published in the June issue of Cell Metabolism suggests that a hormone may explain the connection between mothers who are poorly nourished and an increased risk of obesity in their children.

8 Jun 2005

Novel targets found for the development of drugs to complement, or replace, statins

A team of investigators from the Uppsala Branch of the Ludwig Institute for Cancer Research (LICR) and Harvard Medical School has uncovered novel targets for the development of drugs that would potentially complement, or replace, statins in treating heart disease.

8 Jun 2005

Study is the first to identify involvement of chromosome 21 in developmental regression autism

A new Cincinnati Children's Hospital Medical Center study links regions of two chromosomes to susceptibility for a type of autism characterized by regression in development. Developmental regression can include the loss of previously acquired language, social skills or both.

8 Jun 2005

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Scientists at Lawrence Livermore National Laboratory (LLNL) and the Linnaeus Centre for Bioinformatics (LCB) at Uppsala University in Sweden have developed a new bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity.

8 Jun 2005

Girls who can't orgasm can blame it on their genes

Scientists have discovered that an inability in some women to acheive an orgasm may have a genetic cause.

8 Jun 2005

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

The great physical diversity that evolution has forged in human beings is in evidence wherever we look, but the genes exhibiting the greatest diversity at the DNA level happen to function in a wholly invisible process: immunity. Genes encoding the Human Leukocyte Antigen (HLA) proteins are among the most diverse in the human genome, and scientists have proposed a number of hypotheses to explain why.

6 Jun 2005

New dopamine transporter gene findings may be relevant for substance abuse, tobacco smoking, and ADHD

Confirming findings in a previous study, Yale researchers observed an altered availability of the dopamine transporter in healthy persons with a genetic variation linked to substance abuse and attention deficit hyperactivity disorder (ADHD).

6 Jun 2005

Statisticians learn how to analyze huge quantities of genetic data

In a conceptual breakthrough, a team of researchers led by statisticians at the Harvard School of Public Health (HSPH) has figured out how to analyze huge quantities of genetic data, surpassing the capabilities of traditional techniques and speeding the quest for understanding the genetic basis of complex diseases such as asthma and diabetes.

6 Jun 2005

Gene linked to lower breast cancer risk

In a presentation at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary, Dr. Uwe Langsenlehner and colleagues from Medical University Graz in Austria showed that a specific genetic variation in a cytokine gene is associated with lower breast cancer risk.

6 Jun 2005

Genetically engineered virus has shown promise as a treatment for patients with colorectal cancer

A single injection of a genetically engineered virus has shown promise as a treatment for patients with colorectal cancer that has spread to the liver, according to preliminary results reported at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary.

6 Jun 2005

Intelligence and genetic disease link

A new study by the University of Utah on Ashkenazi Jews has suggested an unusual link between their genetic diseases and their higher intellectual ability.

6 Jun 2005

Toxic chemicals that poisoned your great-grandparents may also damage your health

New U.S. research is suggesting that chemicals can change the way genes work and that toxic chemicals that poisoned your great-grandparents may also damage your health.

5 Jun 2005

Genetic News and Research

Accumulation of genetic changes is not solely determined by natural selection

Exposing SMA-affected cells to aminoglycoside drugs can increase SMN

Research opens up new directions for studying prion diseases in humans

MicroRNAs play an important role in human cancer

New study shows tiny RNAs intimately associated with cancer

Researchers link aberrant 'microRNA' expression to human cancer

Several minute intermediate stage in virus-cell fusion may represent a window of opportunity for drug development

New understanding of microRNAs

Missing link between mothers' diets and obesity in kids

Novel targets found for the development of drugs to complement, or replace, statins

Study is the first to identify involvement of chromosome 21 in developmental regression autism

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Girls who can't orgasm can blame it on their genes

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

New dopamine transporter gene findings may be relevant for substance abuse, tobacco smoking, and ADHD

Statisticians learn how to analyze huge quantities of genetic data

Gene linked to lower breast cancer risk

Genetically engineered virus has shown promise as a treatment for patients with colorectal cancer

Intelligence and genetic disease link

Toxic chemicals that poisoned your great-grandparents may also damage your health

Genetics & Genomics - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Latest News