Genetic News and Research

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Schizophrenia may arise from a single genetic defect

Researchers have long puzzled over the apparently multiple causes of complex developmental disorders such as schizophrenia. Individuals seem to be predisposed to the disease by a tragic, mysterious combination of genetics, prenatal trauma, viral infection, and early experience.

16 Feb 2005

$Link between lactose malabsorption and the occurrence of bone fracture in elderly people$

Link between lactose malabsorption and the occurrence of bone fracture in elderly people

Published in January and conducted by researchers from the Universities of Helsinki and Kuopio and the National Public Health Institute, the study investigated the relation between the genotype associated with lactose malabsorption and the occurrence of bone fracture in the elderly. The study included 483 elderly people in the City of Vantaa – 377 women and 106 men – all over 85 years of age.

16 Feb 2005

Genetic manipulation cuts nerve damage, boosts life span

A novel genetic manipulation significantly extends the life spans of flies by reducing the amount of wear and tear suffered by nerve cells in adults, according to new work published in Cell Metabolism. The findings support the idea that therapies designed to protect the adult nervous system by curbing the production of damaging free radicals might effectively increase longevity in other animals, including humans, the researchers said.

15 Feb 2005

Novel genetic test helps detect mutations that may be missed by conventional DNA test

Researchers have identified a genetic test that when used with DNA testing would detect a higher number of genetic mutations in colorectal cancer patients, according to a study in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

New technique to identify fetal genetic material from amniotic fluid

A preliminary report suggests that cell-free fetal messenger RNA (ribonucleic acid) can be extracted from amniotic fluid (fluid around the fetus), and then be analyzed to study gene expression changes that may reflect the well-being of the fetus, according to a paper in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

New simple and cost-effective method of diagnosing hereditary genetic disorders

A technique called size-fractionation performed on a sample of the mother's blood allows researchers to identify fetal DNA molecules separate from maternal DNA as a way to determine which pregnancies may be at risk for genetic disorders, according to a preliminary communication in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

Angiogenesis inhibitor molecules defend against the development and spread of cancer

Research led by investigators at Beth Israel Deaconess Medical Center (BIDMC) helps explain how a group of angiogenesis inhibitor molecules serve as an important defense mechanism against the development and spread of cancer, offering key insights into why cancerous tumors grow at different rates among different individuals.

15 Feb 2005

Exposure of expectant mothers to urban air pollution may alter the structure of babies' chromosomes while in the womb

A new study of 60 newborns in New York City reveals that exposure of expectant mothers to combustion-related urban air pollution may alter the structure of babies' chromosomes while in the womb.

15 Feb 2005

The link between intelligence and dementia

Scientists have turned to the brightest brains in Britain in a bid to understand the link between intelligence and dementia.

15 Feb 2005

Discovery may have implications for the treatment of hemophilia A and B

University of North Carolina at Chapel Hill researchers have made a discovery that may have implications for the treatment of liver-based genetic defects such as hemophilia A and B in humans.

15 Feb 2005

Genetically engineered potatoes offer new hope in the fight against the Hepatitis B

Genetically engineered potatoes offer new hope in the fight against the Hepatitis B Virus (HBV), an acute sometimes fatal form of viral hepatitis caused by a DNA virus that persists in the blood serum and is transmitted by sexual contact or by transfusion or by ingestion of contaminated blood or other bodily fluids.

14 Feb 2005

Patent-based regulation of genetic resources could undermine health in developing countries

The Australian APEC Study Centre has released a report showing how proposals for a patent-based regime to regulate access to genetic resources could inhibit efforts to protect biodiversity and undermine health in developing countries.

14 Feb 2005

Blips and AIDS therapy

Researchers at Johns Hopkins have concluded that sudden, temporary spikes in the amount of HIV in the body, commonly called blips, do not always mean the virus is developing resistance to AIDS drugs.

14 Feb 2005

Bionomics goes for aggressive strategy in 2005

Australian biotech, Bionomics gave an investor presentation in Melbourne on 2 February 2005 and outlined a bolder, more aggressive strategy. There are many Australian biotech companies with big aspirations.

13 Feb 2005

Two-step approach to transform HIV into a cancer-seeking machine

Camouflaging an impotent AIDS virus in new clothes enables it to hunt down metastasized melanoma cells in living mice, reports a UCLA AIDS Institute study in the Feb. 13 online edition of Nature Medicine.

13 Feb 2005

What influences your choice of valentine?

Scientists at the University of Liverpool have discovered why people are attracted to certain facial types when in pursuit of romance.

13 Feb 2005

Scientists show knocking out key signals will cause diabetes

Using a revolutionary technique to turn off chemical signals inside the cell, scientists at Joslin Diabetes Center have discovered that the different metabolic abnormalities present in type 2 diabetes can be caused by knocking out two key signals in liver cells.

11 Feb 2005

Sudden emotional stress can result in severe but reversible heart muscle weakness

Shocking news, such as learning of the unexpected death of a loved one, has been known to cause catastrophic events, such as a heart attack.

10 Feb 2005

First evidence of cardiac progenitor cells

The first evidence of cardiac progenitor cells – rare, specialized stem cells located in the newborn heart of rats, mice and humans – has been shown by researchers at the University of California, San Diego (UCSD) School of Medicine. The cells are capable of differentiation into fully mature heart tissue.

10 Feb 2005

Patients with cancer have a 7-fold increased risk for blood clots in the legs or lungs

Studies that identify patients at highest risk of thrombosis are scarce, according to background information in the article. It is unclear what risks are for various types and stages of cancer.

9 Feb 2005

Genetic News and Research

Schizophrenia may arise from a single genetic defect

Link between lactose malabsorption and the occurrence of bone fracture in elderly people

Genetic manipulation cuts nerve damage, boosts life span

Novel genetic test helps detect mutations that may be missed by conventional DNA test

New technique to identify fetal genetic material from amniotic fluid

New simple and cost-effective method of diagnosing hereditary genetic disorders

Angiogenesis inhibitor molecules defend against the development and spread of cancer

Exposure of expectant mothers to urban air pollution may alter the structure of babies' chromosomes while in the womb

The link between intelligence and dementia

Discovery may have implications for the treatment of hemophilia A and B

Genetically engineered potatoes offer new hope in the fight against the Hepatitis B

Patent-based regulation of genetic resources could undermine health in developing countries

Blips and AIDS therapy

Bionomics goes for aggressive strategy in 2005

Two-step approach to transform HIV into a cancer-seeking machine

What influences your choice of valentine?

Scientists show knocking out key signals will cause diabetes

Sudden emotional stress can result in severe but reversible heart muscle weakness

First evidence of cardiac progenitor cells

Patients with cancer have a 7-fold increased risk for blood clots in the legs or lungs

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