Antibodies News and Research

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ACTG to present data highlighting a new therapeutic for COVID-19 at the virtual IDWeek 2021

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, which recently expanded its focus to include evaluating outpatient treatment for COVID-19, today announced that Teresa H. Evering, M.D., M.S., a co-lead investigator (with Eric S. Daar, M.D.) for BRII-196/BRII-198 in the ACTIV-2 study of Outpatient Monoclonal Antibodies and Other Therapies, will present data for the monoclonal antibody combination at the virtual IDWeek 2021 conference, taking place September 29 – October 3, 2021.

30 Sep 2021

SARS-CoV-2 infection aided by antibody-dependent enhancement

The coronavirus disease 2019 (COVID-19) pandemic has raised concerns about the detrimental effects of antibodies. Antibody-dependent enhancement (ADE) of infection is one of the biggest concerns in terms of not only the antibody reaction to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon reinfection with the virus but also the reaction to COVID-19 vaccines.

30 Sep 2021

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Now, in a new news study posted to the bioRxiv* preprint server, researchers have successfully induced similar chronicity associated with SARS-CoV-2 infection in MISTRG6-hACE2 humanized mice.

29 Sep 2021

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

A new study aimed to determine the course of SARS-CoV-2 infection in children suffering from rheumatic disease and were receiving bDMARD treatment.

29 Sep 2021

Immunocompromised patients show decreased response to SARS-CoV-2 mRNA vaccines

Researchers explore the germinal cell responses in both healthy individuals and kidney transplant patients in their recent study.

29 Sep 2021

Study finds strong evidence of transplacental passage of IgG antibodies following COVID vaccination

In the current study, researchers investigate the transplacental transmission of antibodies in vaccinated pregnant women.

29 Sep 2021

Large-scale SARS-CoV-2 spike protein mutants analysis identifies subclonal variants indicative of within-host viral diversity

Researchers have investigated a vast SARS-CoV-2 assembly and NGS data set to detect non-synonymous S protein mutations.

29 Sep 2021

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

An observational study compares immune responses against three vaccines.

29 Sep 2021

Aptamer Group collaborates with BizCom to market Optimer discovery and development services in Japan

Aptamer Group and BizCom announce collaboration for Optimer distribution and marketing services in Japan.

From Aptamer Group 29 Sep 2021

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

A new preprint describes the causal role of waning antibody titers in decreased antibody persistence at one year.

29 Sep 2021

Two proteins joined together using a free-standing, rigid link

Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance and angle, much the way a barbell handle connects two weights.

29 Sep 2021

How effective are COVID-19 vaccines against SARS-CoV-2 variants of concern?

The authors from this paper performed a systematic review and meta-analysis evaluating vaccine effectiveness from RCTs and observational studies.

29 Sep 2021

Quantification of antibody titers against SARS-CoV-2 variants elicited by BNT162b2 vaccine

A new study discusses the development of dedicated reagents against the SARS-CoV-2 spike protein through the use of an automated CLEIA system.

28 Sep 2021

The effectiveness of mRNA BNT162b2 vaccine in reducing severe COVID-19: Evidence from Germany

A new study discusses the epidemiology of the outbreak in German nursing homes and the preventive measures undertaken.

28 Sep 2021

New findings highlight the need to expand the toolbox to fight against COVID-19

When Kamlendra Singh flew back to Missouri from India in April, he developed a cough and fever on the plane, despite being vaccinated for COVID-19 and testing negative for the virus right before departure.

28 Sep 2021

Classic antidepressants show potential to enhance modern cancer treatments

Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term.

28 Sep 2021

Hamilton and Rhinostics Reinvent Rapid Swab-Based Sample Workflows from Collection to Processing

Hamilton Company and Rhinostics are combining their respective strengths to improve the speed and quality of nasal and nasopharyngeal sample workflows.

From Hamilton Process Analytics 28 Sep 2021

COVID-19 vaccination reduces risk and duration of SARS-CoV-2 infection

In a study conducted at the European Institute of Oncology, scientists have found that the risk and duration of SARS-CoV-2 infection reduced significantly after COVID-19 vaccination.

28 Sep 2021

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Researchers from the University of Oxford and the University of Warwick have collaborated to develop a method to better understand and evaluate these pleiomorphisms.

28 Sep 2021

Evidence of persisting autoreactivity in post-acute sequelae of SARS-CoV-2 infection?

It has been demonstrated in recent studies that there is a significant breadth of emerging autoreactivity associated with severe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. More specifically, researchers from Emory University have identified a relaxation of peripheral tolerance within early antibody secretion cells that arise in individuals infected with SARS-CoV-2, as important drivers of those responses.

28 Sep 2021

Antibodies News and Research

ACTG to present data highlighting a new therapeutic for COVID-19 at the virtual IDWeek 2021

SARS-CoV-2 infection aided by antibody-dependent enhancement

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Effect of biologic therapy on COVID-19 in children suffering from rheumatic diseases

Immunocompromised patients show decreased response to SARS-CoV-2 mRNA vaccines

Study finds strong evidence of transplacental passage of IgG antibodies following COVID vaccination

Large-scale SARS-CoV-2 spike protein mutants analysis identifies subclonal variants indicative of within-host viral diversity

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

Aptamer Group collaborates with BizCom to market Optimer discovery and development services in Japan

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

Two proteins joined together using a free-standing, rigid link

How effective are COVID-19 vaccines against SARS-CoV-2 variants of concern?

Quantification of antibody titers against SARS-CoV-2 variants elicited by BNT162b2 vaccine

The effectiveness of mRNA BNT162b2 vaccine in reducing severe COVID-19: Evidence from Germany

New findings highlight the need to expand the toolbox to fight against COVID-19

Classic antidepressants show potential to enhance modern cancer treatments

Hamilton and Rhinostics Reinvent Rapid Swab-Based Sample Workflows from Collection to Processing

COVID-19 vaccination reduces risk and duration of SARS-CoV-2 infection

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Evidence of persisting autoreactivity in post-acute sequelae of SARS-CoV-2 infection?

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