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Development of a rapid, inexpensive and highly accurate diagnostic method to fight African Swine Fever

While the attention of public health authorities has been rivetted on the current COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, many other viruses have been stealthily circling the globe, causing serious disease and death in humans and other animals.

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

A research team led by Professor Kelvin Yeung Wai-kwok and Dr Jasper Chan Fuk-woo from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that SARS-CoV-2 infection can cause inflammatory activation of bone resorption cells, leading to severe bone loss during the acute and post-recovery phases of COVID-19.

25 May 2022

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Researchers assessed deep learning workflows involved in CT scans of COVID-19.

25 May 2022

Beckman Coulter Life Sciences announces contest, products for centrifugation milestone

Leading the way since 1947 with automation and innovation in centrifugation, Beckman Coulter Life Sciences announces a series of events to celebrate its 75th anniversary.

From Beckman Coulter Life Sciences - Flow Cytometry 25 May 2022

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Researchers assessed the effectiveness of two orally administered antiviral medications, nirmatrelvir/ritonavir, and molnupiravir, in decreasing hospitalization and deaths among real-world non-hospitalized COVID-19 patients in Hong Kong.

25 May 2022

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

A recent study currently under review at Scientific Reports journal and posted to the Research Square* preprint server demonstrated a potential positive correlation between reactogenicity and immunogenicity of coronavirus disease 2019 (COVID-19) vaccination.

25 May 2022

The root causes of long-COVID still a mystery

In a recent article posted to the journal Annals of Internal Medicine, researchers presented baseline outcomes from a longitudinal assessment of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC), also known as long-COVID.

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

Study reports on the first instances of in-hospital, household transmission of monkeypox

A new retrospective study of seven patients diagnosed with monkeypox in the UK between 2018 and 2021, suggests that some antiviral medications might have the potential to shorten symptoms and reduce the amount of time a patient is contagious.

24 May 2022

Study expands understanding of the eye's immune response to viral infections

The cornea - the transparent protective outer layer of the eye critical to helping us see – produces a delicate and limited immune response to fight infections without damaging our vision, according to a ground-breaking new study from the Peter Doherty Institute for Infection and Immunity (Doherty Institute).

24 May 2022

Normal brain aging accelerated by 26% in people with progressive type 2 diabetes, study shows

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Study identifies a gene that plays an important role in embryo development

A new study co-led by a Cedars-Sinai investigator identified a gene that plays an important role in a biological pathway involved in embryo development.

24 May 2022

Research provides insight into genetic mechanisms of Wilms tumor

New research from Ann & Robert H. Lurie Children's Hospital of Chicago and collaborators from other institutions provides insights into some of the genetic characteristics resulting in the development of relapse in patients with Wilms tumor (nephroblastoma), the most common type of pediatric cancer of the kidney.

24 May 2022

Gallstone disease may be a way to better diagnose deadly pancreatic cancer

Patients with pancreatic ductal adenocarcinoma (PDAC) were six times more likely to have had gallstone disease within the year prior to diagnosis than non-cancer patients, suggesting gallstones could be a warning sign for this aggressive and deadly cancer, according to research to be presented at Digestive Disease Week (DDW) 2022.

24 May 2022

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Across the world, food allergies are on the rise. One of the most important cells in studying this ailment are basophils, which activate inflammation and other responses to allergens such as rashes, and sometimes, anaphylaxis.

23 May 2022

Laboratory News and Research

Development of a rapid, inexpensive and highly accurate diagnostic method to fight African Swine Fever

New imaging approach helps scientists build a complete picture of brain networks

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Beckman Coulter Life Sciences announces contest, products for centrifugation milestone

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

The root causes of long-COVID still a mystery

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Study unveils the novel driver of cardiomyocyte loss

Hydration restores airway integrity in people with cystic fibrosis

Study reports on the first instances of in-hospital, household transmission of monkeypox

Study expands understanding of the eye's immune response to viral infections

Normal brain aging accelerated by 26% in people with progressive type 2 diabetes, study shows

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Study identifies a gene that plays an important role in embryo development

Research provides insight into genetic mechanisms of Wilms tumor

Gallstone disease may be a way to better diagnose deadly pancreatic cancer

Using microfluidics and magnets to isolate rare, allergen-reactive white blood cells

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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