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Enhanced informatics tool could help better identify nonfatal opioid overdose cases in the ED

A team of researchers at the Medical University of South Carolina has been awarded $3.75 million by the National Center for Advancing Translational Sciences to enhance an existing informatics tool known as "informatics for integrating biology and the bedside" or I2B2.

24 Oct 2019

Gene linked to schizophrenia likely confers risk for illness

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients.

24 Oct 2019

Optimal implementation of existing, new interventions essential to end HIV pandemic

Optimal implementation of existing HIV prevention and treatment tools and continued development of new interventions are essential to ending the HIV pandemic, National Institutes of Health experts write in a commentary Clinical Infectious Diseases.

24 Oct 2019

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

A clinical trial in which healthy adults will be deliberately infected with influenza virus under carefully controlled conditions is recruiting volunteers at four Vaccine and Treatment Evaluation Units (VTEUs) supported by NIH's National Institute of Allergy and Infectious Diseases.

24 Oct 2019

UA Little Rock receives $5.6 million DOD grant to advance bone regeneration technology

The U.S. Department of Defense has awarded the University of Arkansas at Little Rock a $5.6 million grant to advance the NuCress scaffold, a groundbreaking bone regeneration technology.

24 Oct 2019

Genetic variations linked to declines in blood oxygen levels during sleep identified

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

24 Oct 2019

Mayo Clinic study explores patient privacy in MRI research

Though identifying data typically are removed from medical image files before they are shared for research, a Mayo Clinic study finds that this may not be enough to protect patient privacy.

24 Oct 2019

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

An international team of experts led by researchers in the Perelman School of Medicine at the University of Pennsylvania and University of Glasgow has been awarded a $9.7 million, five-year grant from the National Institute of Neurological Disorders and Stroke and National Institute for Aging to establish CONNECT-TBI--a program spanning 12 institutions which will study traumatic brain injury and related neurodegenerative diseases.

24 Oct 2019

Lowest-paid workers have three more years of retirement compared to their counterparts

The lowest-paid workers in the UK have three more years of retirement on average compared to their professional counterparts, but are more likely to suffer ill health after stopping work, a new UCL-led study suggests.

24 Oct 2019

Gulf War Illness and chronic fatigue syndrome are two very distinct diseases of the brain

Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise).

23 Oct 2019

NIA-funded study to examine overall benefits and risks of statins in older adults

The National Institute on Aging has funded a major study to examine the overall benefits and risks of cholesterol-lowering drugs known as statins in adults age 75 or older without cardiovascular disease.

23 Oct 2019

SLU research halts toxic protein linked to muscular dystrophy in animal models

There is no cure or treatment for facioscapulohumeral muscular dystrophy, an illness that starts with facial, shoulder and upper arm weakness and eventually affects nearly all skeletal muscles of those with the disease.

23 Oct 2019

Researchers discover new details about several proteins implicated in cancer

Researchers from the Stowers Institute for Medical Research have uncovered new details about several proteins implicated in tumor growth and metastasis, opening a potential avenue for the development of treatments for diseases such as breast cancer.

23 Oct 2019

High levels of dietary salt can activate a brain pathway to cause cognitive impairment

High levels of dietary salt can activate a pathway in the brain to cause cognitive impairment, according to a new study. The paper, which was published in Nature, shows that this effect is not due to a loss in blood flow to the brain as originally thought, but rather to clumps of a protein linked to several forms of dementia in humans.

23 Oct 2019

New study indicates a way to improve cancer immunotherapy

Cancer immunotherapy drugs trigger the body's immune system to attack tumors and have revolutionized the treatment of certain cancers, such as lymphoma, lung cancer and melanoma. Yet, while some patients respond well to the drugs, others don't respond at all. Cancer immunologists want to change that.

23 Oct 2019

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease and HIV.

23 Oct 2019

Zebrafish study provides new insights into the cause of congenital hearing disorders

A study of the genetic make-up of zebrafish has provided brand new insights into the cause of congenital hearing disorders in humans.

23 Oct 2019

Therapy for common vision disorder fails to improve children's reading test scores

Results from a clinical trial funded by the National Eye Institute (NEI) show that while vision therapy can successfully treat convergence insufficiency (CI) in children, it fails to improve their reading test scores.

23 Oct 2019

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

The National Institute on Drug Abuse, part of the National Institutes of Health, awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.

23 Oct 2019

WPI biomedical engineer is creating a new robot to detect and monitor prostate cancer

A biomedical engineer at Worcester Polytechnic Institute is creating a new medical robot that uses minimally invasive technologies to safely and accurately detect and monitor prostate cancer, the second-leading cause of cancer-related deaths among American men.

22 Oct 2019

Medical Research News and Research

Enhanced informatics tool could help better identify nonfatal opioid overdose cases in the ED

Gene linked to schizophrenia likely confers risk for illness

Optimal implementation of existing, new interventions essential to end HIV pandemic

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

UA Little Rock receives $5.6 million DOD grant to advance bone regeneration technology

Genetic variations linked to declines in blood oxygen levels during sleep identified

Mayo Clinic study explores patient privacy in MRI research

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

Lowest-paid workers have three more years of retirement compared to their counterparts

Gulf War Illness and chronic fatigue syndrome are two very distinct diseases of the brain

NIA-funded study to examine overall benefits and risks of statins in older adults

SLU research halts toxic protein linked to muscular dystrophy in animal models

Researchers discover new details about several proteins implicated in cancer

High levels of dietary salt can activate a brain pathway to cause cognitive impairment

New study indicates a way to improve cancer immunotherapy

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

Zebrafish study provides new insights into the cause of congenital hearing disorders

Therapy for common vision disorder fails to improve children's reading test scores

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

WPI biomedical engineer is creating a new robot to detect and monitor prostate cancer

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