Protein Synthesis News and Research

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New insights into modified nucleoside synthesis

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis system.

19 Jul 2024

Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children's Hospital has revealed that an immune protein impacts neuronal protein synthesis in the aging brain.

15 Jul 2024

How short-term nighttime carb restriction boosts exercise and burns fat

Dietary modifications, like the sleep-low method, may improve exercise performance by optimizing glycogen storage and fat metabolism. A study in Nutrients shows night-time carbohydrate restriction benefits endurance and weight management.

10 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Ribosomes and ZAK protein spur the cell's initial response to UV radiation damage

In a recent study, researchers at Johns Hopkins Medicine suggest the cell's messenger RNA (mRNA) -; the major translator and regulator of genetic material -; along with a critical protein called ZAK, spur the cell's initial response to UV radiation damage and play a critical role in whether the cell lives or dies.

2 Jul 2024

Gprc5a identified as potential drug target for treating osteoporosis

Osteoporosis is a skeletal condition that leads to the weakening of bones, making them porous, fragile, and prone to breakage.

18 Jun 2024

Genome sequencing identifies genetic disorders missed by exome analysis

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

10 Jun 2024

New therapeutic target discovered for treatment-resistant melanoma

An international research team led by scientists from the University of Liège (Belgium) has discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies.

8 Jun 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

Disabling survival pathways could be a promising strategy for brain tumor treatment

When you disable the brakes on a race car, it quickly crashes. Dr. Barak Rotblat wants to do something similar to brain cancer cells.

20 May 2024

New modular epigenome editing platform sheds light on gene regulation mechanisms

Understanding how genes are regulated at the molecular level is a central challenge in modern biology.

9 May 2024

Wild Sumatran orangutan uses medicinal plant to treat facial wound

Researchers documented the first observed case of a wild Sumatran orangutan actively treating a wound using a medicinal plant, offering insights into the origins of self-medication in non-human species.

5 May 2024

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts.

30 Apr 2024

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.

25 Apr 2024

Study reveals key protein's role in balancing immune response to viral infections

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

18 Apr 2024

Long genes linked to faster biological aging

What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.

21 Mar 2024

Ricoh and ERS Genomics enter into CRISPR/Cas9 license agreement

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From ERS Genomics 13 Mar 2024

Fenugreek seeds: A superfood for health and wellness, says new review

Research highlights the dietary significance and potential applications of fenugreek seeds, emphasizing their role in disease prevention, chronic condition management, and providing nutritional value, including their ability to reduce blood sugar and cholesterol levels.

27 Feb 2024

Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

The genetic basis of anxiety disorders, identify genetic loci, and calculate polygenic risk scores for anxiety.

20 Feb 2024

Novel synthetic antibiotic effective against drug-resistant bacteria

A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.

15 Feb 2024