Major Depressive Disorder News and Research

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Major Depressive Disorder (MDD) is a psychiatric condition characterized by depressed mood or anhedonia (significant loss of interest or pleasure). The condition affects more than 15.7 million adults and approximately 3 million adolescents (aged 13 to 17 years) in the USA each year.

Treating metabolic abnormalities may improve symptoms in patients with treatment-resistant depression

Identifying and treating metabolic deficiencies in patients with treatment-resistant depression can improve symptoms and in some cases even lead to remission, according to new research from the University of Pittsburgh School of Medicine published online today in the American Journal of Psychiatry.

12 Aug 2016

Transcranial alternating current stimulation during sleep can enhance memory in healthy people

When you sleep, your brain is busy storing and consolidating things you learned that day, stuff you'll need in your memory toolkit tomorrow, next week, or next year. For many people, especially those with neurological conditions, memory impairment can be a debilitating symptom that affects every-day life in profound ways

28 Jul 2016

New study shows women with ADHD likely to have many mental, physical health problems

Women with ADHD are much more likely to have a wide range of mental and physical health problems in comparison to women without ADHD, according to a new study from researchers at the University of Toronto.

21 Jul 2016

Non-drug solutions for postpartum depression: an interview with Dr David Brock & Christopher Thatcher

Postpartum depression (PPD) is reported to occur in 10-15% of delivering women with an estimated 400,000 women affected annually in the US. It is the most common complication of childbirth and is a significant public health concern.

11 Jul 2016

Study finds dramatic increase in nonmedical use of prescription opioids in the U.S.

Nonmedical use of prescription opioids more than doubled among adults in the United States from 2001-2002 to 2012-2013, based on a study from the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health. Nearly 10 million Americans, or 4.1 percent of the adult population, used opioid medications in 2012-2013 a class of drugs that includes OxyContin and Vicodin, without a prescription or not as prescribed (in greater amounts, more often, or longer than prescribed) in the past year.

23 Jun 2016

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Mayo Clinic is highlighting the potential merits of using precision medicine in prescribing antidepressants. Details appear in the current issue of Mayo Clinic Proceedings.

21 Jun 2016

Study shows childhood adversities, sleep disturbances interfere with immune system regulation

Adverse childhood experiences and sleep disturbances interfere with immune system regulation, shows research from the University of Eastern Finland.

20 Jun 2016

Childhood exposure to chronic parental domestic violence linked to suicide attempts among adults

A new study by the University of Toronto, found the lifetime prevalence of suicide attempts among adults who had been exposed to chronic parental domestic violence during childhood was 17.3% compared to 2.3% among those without this childhood adversity.

10 Jun 2016

New research offers hope for patients struggling with major depression

A new study reports that approximately two in five adults (39%) who have experienced major depression are able to achieve complete mental health. Researchers consider complete mental health as occurring when people achieve almost daily happiness or life satisfaction, positive social and psychological well-being, and are also free of depression, anxiety, suicidal thoughts and substance abuse for at least one full year.

8 Jun 2016

Study demonstrates effectiveness of NeuroStar TMS Therapy System in women with postpartum depression

An unfortunate fact facing mothers in the U.S. is that postpartum depression is the most common complication of childbirth. Approximately 10 to 15 percent of women who give birth each year – or roughly 600,000 women – experience postpartum depression symptoms.

18 May 2016

New study links altered purine metabolism to major depressive disorder

People suffering from major depressive disorder may have altered purine metabolism, according to a new study from the University of Eastern Finland and Kuopio University Hospital.

17 May 2016

Low adiponectin levels may lead to development of PTSD symptoms

Individuals with post-traumatic stress disorder (PTSD) relive past traumas again and again, bound in a virtual prison of their memories.

12 May 2016

Study shows risk of developing MDD depends on symptom centrality in network

A novel study published in the current issue of Psychotherapy and Psychosomatics discloses how depression may develop.

10 May 2016

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

An investigation published in the current issue of Psychotherapy and Psychosomatics indicates that mindfulness based cognitive therapy (MBCT) is most helpful when antidepressant drugs are not used.

10 May 2016

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Neuroimaging studies of interconnected brain networks may provide the "missing links" between behavioral and biological models of cognitive vulnerability to depression, according to a research review in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.

10 May 2016

Depressed moms not physiologically 'in sync' with their children

Mothers with a history of depression are not physiologically "in sync" with their kids, according to a new study from Binghamton University. While researchers have known for a while that depression is associated with interpersonal problems with others, this is the first study to examine whether this is also evident physiologically.

6 May 2016

RADAR-CNS programme aims to improve lives of patients with brain disorders

A major new research program supported by the Innovative Medicines Initiative launches today, which will develop new ways of monitoring major depressive disorder, epilepsy, and multiple sclerosis using wearable devices and smartphone technology.

27 Apr 2016

New meta-analysis supports link between intake of omega-3 fatty acids and reduction in MDD

According to the World Health Organization, depression is a major cause of disease burden worldwide, affecting an estimated 350 million people. According to the National Institutes of Mental Health, in 2014, an estimated 15.7 million adults aged 18 or older in the United States had at least one major depressive episode in the past year.

18 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

New imaging study shows how exercise affects the brain

People who exercise have better mental fitness, and a new imaging study from UC Davis Health System shows why. Intense exercise increases levels of two common neurotransmitters -- glutamate and gamma-aminobutyric acid, or GABA -- that are responsible for chemical messaging within the brain.

27 Feb 2016

Major Depressive Disorder News and Research

Further Reading

Treating metabolic abnormalities may improve symptoms in patients with treatment-resistant depression

Transcranial alternating current stimulation during sleep can enhance memory in healthy people

New study shows women with ADHD likely to have many mental, physical health problems

Non-drug solutions for postpartum depression: an interview with Dr David Brock & Christopher Thatcher

Study finds dramatic increase in nonmedical use of prescription opioids in the U.S.

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Study shows childhood adversities, sleep disturbances interfere with immune system regulation

Childhood exposure to chronic parental domestic violence linked to suicide attempts among adults

New research offers hope for patients struggling with major depression

Study demonstrates effectiveness of NeuroStar TMS Therapy System in women with postpartum depression

New study links altered purine metabolism to major depressive disorder

Low adiponectin levels may lead to development of PTSD symptoms

Study shows risk of developing MDD depends on symptom centrality in network

Mindfulness-based cognitive therapy more beneficial without antidepressant drugs

Neuroimaging studies offer new insights into cognitive vulnerability to depression

Depressed moms not physiologically 'in sync' with their children

RADAR-CNS programme aims to improve lives of patients with brain disorders

New meta-analysis supports link between intake of omega-3 fatty acids and reduction in MDD

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

New imaging study shows how exercise affects the brain

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