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Researchers make breakthrough in gene therapy for sickle cell disease

Researchers at the National Institutes of Health have developed a new and improved viral vector--a virus-based vehicle that delivers therapeutic genes--for use in gene therapy for sickle cell disease.

2 Oct 2019

Researchers propose potential treatment for Ewing sarcomas

Ewing sarcoma is a bone cancer that appears mainly in teenagers. Due to a single defective gene, once it spreads to distant organs it is hard to treat. Researchers at the Weizmann Institute of Science have discovered molecular interactions underlying Ewing sarcomas and proposed a potential treatment, which has shown promise in a study in mice.

2 Oct 2019

Medical professional offers unique perspective as father of a child with rare movement disorder

From a professional standpoint, Nathan Hoot, MD, PhD, understands the value of medical research that leads to new, groundbreaking drugs in the treatment of rare diseases.

1 Oct 2019

Study assesses treatment options in African Americans with poorly controlled asthma

A new study of African Americans with poorly controlled asthma, found differences in patients' responses to commonly used treatments. Contrary to what researchers had expected, almost half of young children in the study responded differently than older children and adults, and than white children in prior studies.

1 Oct 2019

Study: Transmission of protozoan parasite may cause leishmaniasis-like symptoms in people

A new study published this week online in Emerging Infectious Diseases suggests that transmission of a protozoan parasite from insects may also cause leishmaniasis-like symptoms in people

1 Oct 2019

UCI biologists make major breakthrough in combating inflammation linked to Alzheimer's

University of California, Irvine biologists blazing new approaches to studying Alzheimer's have made a major finding on combating inflammation linked to the disease.

1 Oct 2019

NIAID initiates new Collaborative Influenza Vaccine Innovation Centers program

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has initiated the Collaborative Influenza Vaccine Innovation Centers program, a new network of research centers that will work together in a coordinated, multidisciplinary effort to develop more durable, broadly protective and longer-lasting influenza vaccines.

30 Sep 2019

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

Complications during first pregnancy linked to increased risk of high blood pressure later in life

Women who experience complications such as preterm births and preeclampsia during their first pregnancy are nearly twice more likely than women without complications to develop high blood pressure later in life--some as quickly as three years later, according to a new study of more than 4,000 women.

30 Sep 2019

High-risk surgical patients with severe aortic stenosis can benefit from new TAVR system

The Portico IDE study found that 30-day safety and one-year effectiveness outcomes of a novel self-expanding transcatheter aortic valve replacement (TAVR) system for patients with severe aortic stenosis (AS) at high or extreme-risk for surgery was noninferior to contemporary FDA-approved TAVR systems available in the United States.

30 Sep 2019

Study shows possibility of diabetes remission with ‘achievable’ weight loss

People who achieve weight loss of 10% or more in the first five years following diagnosis with type 2 diabetes have the greatest chance of seeing their disease go into remission, according to a study led by the University of Cambridge.

30 Sep 2019

Study: Revascularization with PCI or CABG prolongs survival in patients with left main disease

Patients with left main coronary artery disease (LMCAD) typically have a poor prognosis due to the large amount of myocardium at risk.

30 Sep 2019

'Good' cholesterol reverses atherosclerosis in the blood vessels of mice with diabetes

Increasing levels of a simplified version of "good" cholesterol reversed disease in the blood vessels of mice with diabetes, a new study finds.

30 Sep 2019

Weight loss is the key in battling type 2 diabetes, study reveals

Type 2 diabetes and obesity have been linked to each other. People who are overweight or obese are at a higher risk of developing type 2 diabetes, which is a chronic disease characterized by increased blood sugar levels.

30 Sep 2019

Nintedanib drug can benefit patients with broad range of scarring lung diseases

Nintedanib, a medication approved for the treatment of idiopathic pulmonary fibrosis, slows the decline in lung function among patients with a broad range of scarring lung diseases.

30 Sep 2019

African American children respond differently to step-up therapies for asthma

African Americans suffer asthma more often and more severely than Caucasian patients. However, clinical trials that have shaped treatment guidelines have included few African Americans.

27 Sep 2019

Study uncovers molecule linking weight gain to gut bacteria

UT Southwestern researchers have found a key driver of the crosstalk that helps synchronize the absorption of nutrients in the gut with the rhythms of the Earth's day-night light cycle.

27 Sep 2019

Polymer drug-eluting and polymer-free drug-coated stents safe and effective for patients with high bleeding risk

The first randomized trial to compare a durable polymer drug-eluting stent to a polymer-free drug-coated stent in patients at high risk of bleeding and treated with one-month dual antiplatelet therapy (DAPT) found that both are clinically safe and effective.

27 Sep 2019

IDEAL LM study: Biodegradable polymer everolimus-eluting stent safe and effective for patients undergoing PCI

New data from the IDEAL-LM trial found that a biodegradable polymer everolimus-eluting stent (BP-EES) followed by four months of dual antiplatelet therapy (DAPT) was safe and effective compared to a conventional durable polymer everolimus-eluting stent (DP-EES) followed by 12 months of DAPT in patients undergoing PCI for unprotected left main coronary artery (uLMCA) disease.

27 Sep 2019

Ticagrelor monotherapy reduces bleeding while preserving ischemic benefit in high-risk PCI patients

New data from the randomized, placebo-controlled TWILIGHT trial found that compared to ticagrelor plus aspirin, ticagrelor monotherapy reduces bleeding events without increasing the risk of death, myocardial infarction, or stroke in high-risk patients who have undergone successful percutaneous coronary intervention and completed three months of dual antiplatelet therapy.

27 Sep 2019

Medical Research News and Research

Researchers make breakthrough in gene therapy for sickle cell disease

Researchers propose potential treatment for Ewing sarcomas

Medical professional offers unique perspective as father of a child with rare movement disorder

Study assesses treatment options in African Americans with poorly controlled asthma

Study: Transmission of protozoan parasite may cause leishmaniasis-like symptoms in people

UCI biologists make major breakthrough in combating inflammation linked to Alzheimer's

NIAID initiates new Collaborative Influenza Vaccine Innovation Centers program

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Complications during first pregnancy linked to increased risk of high blood pressure later in life

High-risk surgical patients with severe aortic stenosis can benefit from new TAVR system

Study shows possibility of diabetes remission with ‘achievable’ weight loss

Study: Revascularization with PCI or CABG prolongs survival in patients with left main disease

'Good' cholesterol reverses atherosclerosis in the blood vessels of mice with diabetes

Weight loss is the key in battling type 2 diabetes, study reveals

Nintedanib drug can benefit patients with broad range of scarring lung diseases

African American children respond differently to step-up therapies for asthma

Study uncovers molecule linking weight gain to gut bacteria

Polymer drug-eluting and polymer-free drug-coated stents safe and effective for patients with high bleeding risk

IDEAL LM study: Biodegradable polymer everolimus-eluting stent safe and effective for patients undergoing PCI

Ticagrelor monotherapy reduces bleeding while preserving ischemic benefit in high-risk PCI patients

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