Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Predicting the development of type 1 diabetes is possible, shows TEDDY study

New research shows that it is possible to predict the development of type 1 diabetes. By measuring the presence of autoantibodies in the blood, it is possible to detect whether the immune system has begun to break down the body's own insulin cells.

26 Feb 2015

Emulsifiers can alter gut microbiota composition to induce intestinal inflammation

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.

26 Feb 2015

Sanofi announces FDA approval of Toujeo insulin to improve glycemic control in people with diabetes

Sanofi announced today that the U.S. Food and Drug Administration approved Toujeo (insulin glargine [rDNA origin] injection, 300 U/mL), a once-daily long-acting basal insulin, to improve glycemic control in adults living with type 1 and type 2 diabetes. Toujeo is expected to be available in the U.S. at the beginning of Q2 2015.

26 Feb 2015

DPP-4 inhibitors effective against low blood sugar levels

DPP-4 inhibitors are a group of drugs used to treat type 2 diabetes that lower high blood sugar levels by stimulating insulin production in the body. Researchers at Lund University in Sweden have now discovered that DPP-4 inhibitors are also effective against low blood sugar levels.

23 Feb 2015

Tandem Diabetes Care announces release of t:simulator App

Tandem Diabetes Care, Inc., a medical device company and manufacturer of the t:slim and t:flex Insulin Pumps, today announced the release of the t:simulator App, which mimics the touchscreen interface and features of the t:slim Insulin Pump.

21 Feb 2015

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

A growth hormone can significantly improve the social impairment associated with autism spectrum disorder (ASD) in patients with a related genetic syndrome, according to a pilot study conducted at the Icahn School of Medicine at Mount Sinai and published yesterday on Pub Med, a public database of biomedical topics maintained by the National Institutes of Health (study originally published in the December 12 issue of the journal Molecular Autism).

20 Feb 2015

New research finds that synthetic flame retardants can cause metabolic and liver problems

Chemicals used as synthetic flame retardants that are found in common household items such as couches, carpet padding, and electronics have been found to cause metabolic and liver problems that can lead to insulin resistance, which is a major cause of obesity, according to new research from the University of New Hampshire.

20 Feb 2015

Sleep loss can lead to diabetes, reveals new research

Lack of sleep can elevate levels of free fatty acids in the blood, accompanied by temporary pre-diabetic conditions in healthy young men, according to new research published online February 19, 2015, in Diabetologia, the journal of the European Association for the Study of Diabetes.

19 Feb 2015

Study: Definitive indicator of diabetes control deceptively high in African-American children

A new study confirms the findings of two earlier LSU Health New Orleans studies that the definitive indicator of diabetes control, the HbA1c, is deceptively high in African-American children.

19 Feb 2015

Dance Biopharm announces completion of $9.5 million convertible note and warrants financing

Dance Biopharm Inc., a privately-held biotechnology company focused on the development of inhaled insulin products to treat diabetes, today announced the completion of a $9.5 million convertible note and warrants financing.

19 Feb 2015

Study shows that plant-based vegan diet may lower heart disease risk in obese children

Obese children who begin a low-fat, plant-based vegan diet may lower their risk of heart disease through improvements in their weight, blood pressure, body mass index, cholesterol levels, insulin sensitivity, and high-sensitivity C-reactive, according to Cleveland Clinic research published online today by The Journal of Pediatrics.

16 Feb 2015

JDRF supports Janssen's DIA approach to combat type 1 diabetes

JDRF, the leading research and advocacy organization funding type 1 diabetes (T1D) research, announced today its alignment with an innovative scientific approach of Janssen Research & Development, LLC (Janssen) and the company's Disease Interception Accelerator (DIA) group, which will focus on transforming type 1 diabetes through its disease interception strategy.

13 Feb 2015

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Astute Medical, Inc., developer of the NephroCheck® Test, today previewed the upcoming AKI & CRRT 2015 conference to be held in San Diego from February 17 to February 20.

13 Feb 2015

Diabetes medication can help white blood cells fight bacterial infections

Pioglitazone, a medication approved for treatment of type 2 diabetes, can help bypass genetic defects in chronic granulomatous disease to help white blood cells fight bacterial infections, according to researchers at National Jewish Health.

12 Feb 2015

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

ChromaDex Corp. announced today that the initial results of the first human clinical study for the company's NIAGEN nicotinamide riboside (NR) has met its primary endpoint.

11 Feb 2015

New type of engineered insulin could improve treatment for diabetes patients

For patients with diabetes, insulin is critical to maintaining good health and normal blood-sugar levels. However, it's not an ideal solution because it can be difficult for patients to determine exactly how much insulin they need to prevent their blood sugar from swinging too high or too low.

11 Feb 2015

Too much folic acid during pregnancy puts daughters at risk of diabetes, obesity later in life

Mothers that take excessive amounts of folic acid during pregnancy may predispose their daughters to diabetes and obesity later in life, according to a new study published today in the Journal of Endocrinology. With high dose supplements being widely available, the study calls for a need to establish a safe upper limit of folic acid intake for pregnant women.

10 Feb 2015

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Chiasma Inc., a U.S. privately-held biopharma company, announced today that results from a multicenter Phase III study of the investigational new drug, octreotide capsules, were published online for early release on Feb. 9, ahead of print, by the Journal of Clinical Endocrinology & Metabolism.

10 Feb 2015

Scientists develop potential new therapy based on cow's immune molecules for hormone deficiencies

To help people with hormone deficiencies, scientists at The Scripps Research Institute have developed a potential new therapy based on an unlikely model: immune molecules from cows.

9 Feb 2015

Endogenous cannabinoids linked to weight gain in people with schizophrenia

Cannabinoids may be involved in the weight gain that occurs in people with schizophrenia who are treated with the antipsychotic olanzapine, according to a pilot study published in the Journal of Clinical Psychopharmacology by researchers at the Institut universitaire en santé mentale de Montréal and Université de Montréal.

5 Feb 2015

Insulin News and Research

Further Reading

Predicting the development of type 1 diabetes is possible, shows TEDDY study

Emulsifiers can alter gut microbiota composition to induce intestinal inflammation

Sanofi announces FDA approval of Toujeo insulin to improve glycemic control in people with diabetes

DPP-4 inhibitors effective against low blood sugar levels

Tandem Diabetes Care announces release of t:simulator App

Study: Growth hormone can improve social impairment in patients with Phelan-McDermid syndrome

New research finds that synthetic flame retardants can cause metabolic and liver problems

Sleep loss can lead to diabetes, reveals new research

Study: Definitive indicator of diabetes control deceptively high in African-American children

Dance Biopharm announces completion of $9.5 million convertible note and warrants financing

Study shows that plant-based vegan diet may lower heart disease risk in obese children

JDRF supports Janssen's DIA approach to combat type 1 diabetes

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Diabetes medication can help white blood cells fight bacterial infections

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

New type of engineered insulin could improve treatment for diabetes patients

Too much folic acid during pregnancy puts daughters at risk of diabetes, obesity later in life

Chiasma announces publication of octreotide capsules Phase III study results in JCEM

Scientists develop potential new therapy based on cow's immune molecules for hormone deficiencies

Endogenous cannabinoids linked to weight gain in people with schizophrenia

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