Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Minimally invasive technique holds promise for removing large brain tumors

A minimally invasive endoscopic procedure holds promise for safely removing large brain tumors from an area at the bottom of the skull, near the sinus cavities, clinical researchers at the Brain Tumor Center at the University of Cincinnati Neuroscience Institute (UCNI) at University Hospital have found.

2 Apr 2010

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

The "cradle" of new neurons in the adult brain is well known. It is what is called the subventricular zone, a tissue structure lining the lateral ventricles. This is where neural or brain stem cells reside, which are responsible for generating new neurons if needed. For many years now, the subventricular zone has been suspected to be the origin of specific malignant brain tumors called gliomas, the most deadly type of which is glioblastoma.

2 Apr 2010

UK NICE recommends Eli Lilly's ALIMTA as maintenance therapy for nonsquamous NSCLC

Eli Lilly and Company announced today that its chemotherapy ALIMTA® (pemetrexed for injection) received a positive "Final Appraisal Determination" from the United Kingdom's National Institute for Health and Clinical Excellence (NICE).

2 Apr 2010

MRI study reveals worry may offset negative effects of fear and depression

A new study of brain activity in depressed and anxious people indicates that some of the ill effects of depression are modified - for better or for worse - by anxiety

2 Apr 2010

Researchers identify link between genetic mutation and schizophrenia

In what may provide the most compelling evidence to date, researchers at Columbia University Medical Center have illuminated how a genetic variant may lead to schizophrenia by causing a disruption in communication between the hippocampus and prefrontal cortex regions of the brain, areas believed to be responsible for carrying out working memory.

2 Apr 2010

Mouse study indicates rapamycin drug prevents Alzheimer's disease, extends lifespan

If research results continue to be repeated and are turned into clinical trials, a drug already approved for some uses could be marshaled - sooner than we expect - to prevent Alzheimer's disease in humans and improve health to the end of life.

2 Apr 2010

New development in treatment of African Sleeping Sickness

African sleeping sickness or Human African Typanosomiasis is a potentially fatal disease affecting 50 to 70 thousand Africans each year. Carried by the bite tsetse fly this fatal disease is actually caused by a tiny parasite that attacks the nervous system, brain, spinal column resulting in mental confusion and finally death.

1 Apr 2010

ImmunoCellular Therapeutics files Annual Report with Securities and Exchange Commission for 2009

ImmunoCellular Therapeutics announced today that it has filed its Annual Report with the Securities and Exchange Commission for the period ended December 31, 2009 on Form 10-K.

1 Apr 2010

BELLUS Health initiates Phase I clinical study for NRM8499

BELLUS Health Inc. announced today that, on March 30, 2010, the Company initiated a Phase I clinical study for NRM8499, a prodrug of tramiprosate. NRM8499 is intended for the treatment of Alzheimer's disease.

1 Apr 2010

UC Irvine Healthcare's heart failure program earns the Gold Seal of Approval

UC Irvine Healthcare's heart failure program and Stroke & Cerebrovascular Center have again earned the Gold Seal of Approval from The Joint Commission, healthcare's predominant standards-setting and accrediting body.

1 Apr 2010

Genetic risk factor for schizophrenia can disrupt connectivity at level of single neurons

The strongest known recurrent genetic cause of schizophrenia impairs communications between the brain's decision-making and memory hubs, resulting in working memory deficits, according to a study in mice.

1 Apr 2010

Insight into how mutations in LRRK2 gene may cause familial Parkinson's disease

Using new one-of-a-kind "mouse models" that promise to have a significant impact on future Parkinson's disease research, Mount Sinai School of Medicine researchers are among the first to discover how mutations in a gene called LRRK2 may cause inherited (or "familial") Parkinson's disease, the most common form of the disease. The study, published in The Journal of Neuroscience, is the first in vivo evidence that LRRK2 regulates dopamine transmission and controls motor performance, and that the mutation of LRRK2 eliminates the normal function of LRRK2, leading to Parkinson's disease.

1 Apr 2010

Four studies of bavituximab and PS-targeting antibodies to be presented at AACR 2010

Peregrine Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing innovative monoclonal antibodies for the treatment of cancer and viral infections, today announced four studies of bavituximab and its other PS-targeting antibodies have been accepted for presentation at the 101st Annual Meeting of the American Association for Cancer Research to be held April 17-21, 2010 in Washington, D.C.

1 Apr 2010

Major breakthrough may help develop low toxicity drugs for sleeping sickness

Scientists from the Drug Discovery Unit at the University of Dundee - working together with partners at the University of York and the Structural Genomics Consortium in Toronto - have made a major breakthrough in identifying new treatments for a fatal disease which infects tens of thousands of Africans each year.

1 Apr 2010

IGEN Networks signs MOU with Bio Business Development

IGEN Networks Corp. is pleased to announce that it has signed a memorandum of understanding with Bio Business Development Corp. International, Inc. to negotiate the acquisition of the exclusive global distribution rights to the patented lateral-flow diagnostic testing platform technology for rapid detection of the infectious prion protein diseases.

1 Apr 2010

Cardiac CT can help identify and predict at risk heart attack patients

One of the largest research studies into cardiac computed tomography (CT), conducted at the University of Ottawa Heart Institute (UOHI), shows that the high-speed advanced imaging technology can identify and predict patients at risk for heart attack and death.

1 Apr 2010

National Doctors' Day: St. Jude Children's Research Hospital honors physicians and staff

As physicians nationwide are acknowledged for their talent, sacrifice and courage on National Doctors' Day, St. Jude Children's Research Hospital honors its more than 230 staff and consulting physicians who strive to fulfill the hospital's mission each day.

31 Mar 2010

Recipients of Pfizer Canada's third Neuropathic Pain Research Awards Competition announced

Pfizer Canada is pleased to announce the recipients of its third Neuropathic Pain Research Awards Competition, which aims to fund and support Canadian innovation within independent neuropathic pain research in the areas of basic biomedical, clinical and health sciences.

31 Mar 2010

Nation's emergency physicians warn parents about dangers of prescription drug abuse

The nation's emergency physicians are issuing a strong warning to parents about the dangers of prescription drug abuse, which are now the second most abused drugs, after marijuana. Nearly three-quarters of a million people (741,425) needed emergency care in 2006 because of prescription drug abuse.

31 Mar 2010

LoJack and May Institute launch campaign to increase public awareness about autism

What does autism look like? Millions of commuters in Massachusetts will find out during April – National Autism Awareness Month – thanks to a powerful public awareness campaign that features photos and stories of children with autism as well as important information about the disorder.

31 Mar 2010

Brain News and Research

Further Reading

Minimally invasive technique holds promise for removing large brain tumors

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

UK NICE recommends Eli Lilly's ALIMTA as maintenance therapy for nonsquamous NSCLC

MRI study reveals worry may offset negative effects of fear and depression

Researchers identify link between genetic mutation and schizophrenia

Mouse study indicates rapamycin drug prevents Alzheimer's disease, extends lifespan

New development in treatment of African Sleeping Sickness

ImmunoCellular Therapeutics files Annual Report with Securities and Exchange Commission for 2009

BELLUS Health initiates Phase I clinical study for NRM8499

UC Irvine Healthcare's heart failure program earns the Gold Seal of Approval

Genetic risk factor for schizophrenia can disrupt connectivity at level of single neurons

Insight into how mutations in LRRK2 gene may cause familial Parkinson's disease

Four studies of bavituximab and PS-targeting antibodies to be presented at AACR 2010

Major breakthrough may help develop low toxicity drugs for sleeping sickness

IGEN Networks signs MOU with Bio Business Development

Cardiac CT can help identify and predict at risk heart attack patients

National Doctors' Day: St. Jude Children's Research Hospital honors physicians and staff

Recipients of Pfizer Canada's third Neuropathic Pain Research Awards Competition announced

Nation's emergency physicians warn parents about dangers of prescription drug abuse

LoJack and May Institute launch campaign to increase public awareness about autism

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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