Androgen News and Research

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Controversial hormone could fight against recurring breast cancers

An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments.

9 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

An international group of researchers report success in mice of a method of using positron emission tomography scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer.

1 Dec 2016

Researchers find timing, duration of androgen exposure can influence genital defects in female mice

University of Florida researchers have identified cells targeted by a male hormone and found that an excess of that hormone at a specific time can cause genital defects in female mice.

8 Nov 2016

Identifying gene defects may help develop individualised treatments for prostate cancer patients

The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualised cancer treatments for patients.

7 Nov 2016

Men can take contraceptives to prevent pregnancy in female partners, study shows

Men can take birth control shots to prevent pregnancy in their female partners, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

27 Oct 2016

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer.

21 Oct 2016

Natural compound found in red wine can lower testosterone levels in women with PCOS

Resveratrol—a natural compound found in red wine and grapes—can help address a hormone imbalance in women with polycystic ovary syndrome (PCOS), a leading cause of infertility in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

19 Oct 2016

Common hormone therapy to treat prostate cancer may increase dementia risk in men

A common hormone therapy to treat prostate cancer may double a man's risk of dementia, regardless of his age, Penn Medicine researchers reported in a study published online today in JAMA Oncology.

14 Oct 2016

Study examines benefits of hormonal therapy for prostate cancer patients with prior history of heart attack

In a recent study, a Yale Cancer Center team determined that men who received hormonal therapy for prostate cancer had a net harm if they had a prior history of a heart attack.

28 Sep 2016

Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.

21 Sep 2016

Scientists find new target that may lead to future treatments for Kennedy's disease

If a disease affects motoneurons, cells that control voluntary muscle activity, researchers should focus their efforts on motoneurons to find potential treatments, right? Not always.

31 Aug 2016

T-sol can be safe and effective treatment for men with hypogonadism

For men with hypogonadism, a condition in which the body does not produce enough testosterone, low sex drive and fatigue are common symptoms.

17 Aug 2016

IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure.

16 Aug 2016

Novel computational analysis of prostate cancer suggests potential targets for therapy

Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate cancer cells to proliferate and evade treatment.

11 Aug 2016

Novel compound holds potential for next-generation prostate cancer treatment

In the search for new ways to attack recurrent prostate cancer, researchers at Duke Health report that a novel compound appears to have a unique way of blocking testosterone from fueling the tumors in mice.

8 Aug 2016

African-American men treated with ADT for prostate cancer suffer from high mortality rates

In a retrospective study analyzing patients' medical records, researchers at Brigham and Women's Hospital found that patients' race significantly affected their longevity by increasing the likelihood of death after receiving androgen deprivation therapy (ADT).

5 Aug 2016

Soy isoflavones may help improve metabolic and cardiovascular health in women with PCOS

Women who have polycystic ovary syndrome (PCOS)—a common cause of female infertility—may be able to improve their metabolic and cardiovascular health by consuming soy isoflavones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.