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New sepsis test could save thousands of lives

Researchers have used a biosensor that can quickly identify biomarkers of sepsis and has the potential to save thousands of lives.

21 Feb 2019

Scientists demonstrate key role of salt in allergic immune reactions

Salt apparently affects allergic immune reactions. A team working with Prof. Christina Zielinski at the Technical University of Munich has demonstrated in cell cultures that salt leads to the formation of Th2 cells.

21 Feb 2019

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system's ability to fight melanoma in mice.

20 Feb 2019

Therapeutic endoscopy has an expanding role in the treatment of IBD

According to a new statement from a panel of national and international experts in gastroenterology, inflammatory bowel disease (IBD) and other areas, interventional (or therapeutic) IBD endoscopy has an expanding role in the treatment of disease and of adverse events from surgery.

15 Feb 2019

Study identifies protein regulator that induces Th17 cells to cause multiple sclerosis

Inflammatory and autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis (MS) are a major healthcare burden worldwide and are life-altering conditions for afflicted patients.

14 Feb 2019

New target appears to aid recovery after optic nerve trauma

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report.

11 Feb 2019

Therapy derived from parasitic worms helps protect against one of chemotherapy's side effects

A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways and reducing inflammation, indicates the first transcriptome-wide profiling of the bladder during ifosfamide-induced hemorrhagic cystitis.

8 Feb 2019

Study reveals how whipworms cause destruction in the gut

Signaling through interleukin-10 (IL-10) receptors on gut immune cells plays a critical role in protecting the gut lining and microbiota from disruption caused by whipworms, according to a study published January 31 in the open-access journal PLOS Pathogens by María Duque-Correa of the Wellcome Sanger Institute in the UK, and colleagues.

1 Feb 2019

Study: IL10 receptor critical to prevent uncontrolled infection and gut damage

A new study has identified the master regulator that maintains a healthy gut and limits damage by parasitic whipworms.

1 Feb 2019

Researchers use mouse models to explain the developmental process behind COPD

The airways and lungs are affected by a range of diseases, but while some have been well characterized and treated, others such as chronic obstructive pulmonary disorder (COPD) are still somewhat of an enigma.

1 Feb 2019

Researchers uncover how the immune system protects from bowel cancer

Researchers from Charité - Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous.

31 Jan 2019

Study shows how skin cancer hijacks the immune system to grow and spread

Scientists have uncovered molecules released by invasive skin cancer that reprogram healthy immune cells to help the cancer to spread.

31 Jan 2019

Low-calorie diet prevents asthma symptoms in mice, study finds

Experimenting with mice, Johns Hopkins Medicine researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet’s fat and sugar content.

31 Jan 2019

Study: Low-calorie diet prevented asthma symptoms in mice

Experimenting with mice, Johns Hopkins Medicine researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet's fat and sugar content.

31 Jan 2019

Researchers design interleukin protein to balance overshooting immune response

Small infections can be fatal: Millions of people die each year from sepsis, an overreaction of the immune system.

23 Jan 2019

Scientists find link between colitis and colon cancer

Lingering inflammation in the colon is a known risk factor for colorectal cancer and now scientists report one way it resets the stage to enable this common and often deadly cancer.

14 Jan 2019

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Spondyloarthritis is one of the most common types of chronic joint inflammation affecting nearly 1-2% of the Western population.

10 Jan 2019

Researchers identify promising therapeutic option to treat multiple sclerosis

Researchers at the Medical Center of Johannes Gutenberg University Mainz (JGU) identified an innovative and promising therapeutic option to treat multiple sclerosis.

10 Jan 2019

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

The hygiene hypothesis may explain why asthma and other allergic airway diseases have dramatically increased over the past decades in industrialized countries.

9 Jan 2019

A small protein plays key role in how cancer stem cells differentiate

A jagged little protein appears to be key to how cancer stem cells differentiate and enable metastasis, according to researchers at Rice University and the Duke University School of Medicine.

4 Jan 2019