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First patients receive doses of antisense drug for Huntington's disease

The first few patients have received doses of an experimental RNA-targeting drug for Huntington's disease, it was announced today.

20 Oct 2015

Road traffic crashes remain too high despite improvements in road safety

Some 1.25 million people die each year as a result of road traffic crashes, according to the WHO's Global status report on road safety 2015, despite improvements in road safety.

20 Oct 2015

TARSA Therapeutics' TBRIA NDA accepted by FDA for review

TARSA Therapeutics, Inc. today announced that its New Drug Application (NDA) for TBRIATM (calcitonin-salmon [rDNA origin] delayed release tablets) submitted to the U.S. Food and Drug Administration (FDA) in July 2015, has been accepted for review, with a PDUFA date of May 30, 2016.

19 Oct 2015

Researchers associate neuroimaging data with reading deficits in patients with left-sided stroke

Researchers at Kessler Foundation and Rutgers University correlated neuroimaging data with reading deficits in patients with subacute left hemispheric stroke. Their findings add to our knowledge of the neural mechanisms of reading and may be useful in the development of reading interventions that address specific neurological deficits.

19 Oct 2015

Digital health app facilitates early detection, treatment of COPD exacerbation symptoms

A digital health application for reporting symptoms of Chronic Obstructive Pulmonary Disease (COPD) facilitated early detection and treatment of COPD exacerbation symptoms, according to an analysis from the Temple Lung Center published by Telemedicine and eHealth.

19 Oct 2015

Doctors use MR-guided focused ultrasound to treat essential tremor

The Ohio State University Wexner Medical Center is one of six locations nationally - and the only one in the Midwest - studying the safety and effectiveness of a promising new technology using MR-guided focused ultrasound to treat patients suffering from essential tremor as part of a multi-center FDA trial.

18 Oct 2015

Sanofi Pasteur, IDRI establish Global Health Vaccine Center of Innovation

In an effort to accelerate timelines and decrease development costs of life-saving vaccines, the Infectious Disease Research Institute (IDRI) and Sanofi Pasteur today announce the establishment of the Global Health Vaccine Center of Innovation (GHVCI), to be headquartered at IDRI in Seattle.

16 Oct 2015

Simple tool can predict individual's life support needs five years in advance

It is now possible to determine which patients have an increased chance of one day needing life support with mechanical ventilation. Researchers have developed a simple tool to predict an individual's five-year risk of requiring this care.

15 Oct 2015

Women with Type 2 diabetes face barrier to physical activity

Women with Type 2 diabetes experience a barrier to physical activity that threatens to make them more sedentary and cause their health to worsen, according to a new study by Amy Huebschmann, MD, MS of the University of Colorado Anschutz Medical Campus.

15 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Scientists have found what could one day lead to a promising treatment for those with a crippling disease, Duchenne muscular dystrophy.

14 Oct 2015

Early physical therapy provides only modest benefits for recent-onset low back pain

Early physical therapy for recent-onset low back pain resulted in statistically significant improvement in disability compared to usual care, but the improvement was modest and did not achieve a difference considered clinically important at the individual patient level, according to a study in the October 13 issue of JAMA.

14 Oct 2015

Lithium can be safe, effective for children suffering from bipolar disorder

A multicenter study of young patients with bipolar disorder provides what may be the most scientifically rigorous demonstration to date that lithium -- a drug used successfully for decades to treat adults with the condition -- can also be safe and effective for children suffering from it.

12 Oct 2015

Survey: Only half of healthcare providers adequately equipped with information about cryptogenic stroke

Results from a new survey from the American Heart Association/American Stroke Association found that only half of healthcare professionals consider themselves to be adequately equipped with information about cryptogenic stroke, a stroke in which the underlying cause is still unknown after extensive testing.

12 Oct 2015

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Three phase III studies being presented at the European Committee for Treatment Research in Multiple Sclerosis congress demonstrate that treating MS with ocrelizumab reduces relapse rate and delay onset of disability progression compared to interferon beta-1a in relapsing forms of MS and disability progression in primary progressive MS compared to placebo.

12 Oct 2015

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

Scientists have calculated more precise measurements of heritability--the influence of underlying genes--in nine autoimmune diseases that begin in childhood. The research may strengthen researchers' abilities to better predict a child's risk for associated autoimmune diseases.

9 Oct 2015

Disability News and Research

First patients receive doses of antisense drug for Huntington's disease

Road traffic crashes remain too high despite improvements in road safety

TARSA Therapeutics' TBRIA NDA accepted by FDA for review

Researchers associate neuroimaging data with reading deficits in patients with left-sided stroke

Digital health app facilitates early detection, treatment of COPD exacerbation symptoms

Doctors use MR-guided focused ultrasound to treat essential tremor

Sanofi Pasteur, IDRI establish Global Health Vaccine Center of Innovation

Simple tool can predict individual's life support needs five years in advance

Women with Type 2 diabetes face barrier to physical activity

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Early physical therapy provides only modest benefits for recent-onset low back pain

Lithium can be safe, effective for children suffering from bipolar disorder

Survey: Only half of healthcare providers adequately equipped with information about cryptogenic stroke

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

New partnership to deliver world-class healthcare through collaborative scientific research

Daclizumab HYP superior to interferon in relapsing–remitting MS

Up to 1 billion people could be at risk of going blind by 2050, say researchers

Head injury patients do not benefit from brain cooling therapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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