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UC San Diego Health participates in nationwide clinical study on hemophilia B gene therapy

The Hemophilia and Thrombosis Treatment Center at UC San Diego Health has joined a nationwide clinical trial testing a potential gene therapy that may one day provide a better and long-lasting treatment for people with hemophilia B.

23 Mar 2016

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

Distinguished Professor Jae Jung, PhD, chair of the Department of Molecular Microbiology & Immunology and the director of the University of Southern California Institute for Emerging Pathogens and Immune Diseases at the Keck School of Medicine of USC, is among this year's recipients of the National Cancer Institute Outstanding Investigator Award.

23 Mar 2016

New reference guide can help HIV care providers treat chronic pain

Recent studies suggest many individuals with HIV have chronic pain. Estimates range from 39 percent all the way to 85 percent. Chronic pain is an important comorbid condition in individuals with HIV, as it is common and causes substantial disability.

22 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Antibodies given within one day of SHIV exposure can clear the virus

Scientists at the Oregon National Primate Research Center today revealed that infant rhesus macaques treated with antibodies within 24 hours of being exposed to SHIV, a chimeric simian virus that bears the HIV envelope protein, were completely cleared of the virus.

22 Mar 2016

World TB Day 2016: WHO calls to Unite to End TB

In advance of World TB Day, to be observed on 24 March, the World Health Organization is calling on countries and partners to Unite to End TB.

22 Mar 2016

Specialized gene editing system paves way to eventual cure for HIV patients

A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS.

22 Mar 2016

N-KICS tool helps describe intensity of nursing care for children with CMC

Recent medical advances have resulted in increased survival of children with complex medical conditions (CMC), such as cerebral palsy, complex chromosomal anomalies, major congenital heart diseases and respiratory disease.

21 Mar 2016

New study provides insight into HIV-dependent immune dysfunction

HIV infection results in a variety of immune abnormalities, which are especially pronounced in individuals with high viral titers. B cells are the antibody producing cells of the immune system and are not directly infected by HIV.

21 Mar 2016

New ultra-sensitive technique shows promise as diagnostic tool for cancers, HIV

A common theme in medicine is that detecting a disease early on can lead to more effective treatments. This relies partly on luck that the patient gets screened at the right time, but more important is that the testing techniques are sensitive enough to register the minuscule hints that diseases leave in the blood stream.

21 Mar 2016

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic test results take time, so many healthcare providers prescribe multi-drug TB treatments as a precaution.

20 Mar 2016

Study associates prevalence of homosexual relations in Uganda with increased health risks

The results are based on a survey with nearly 3,000 participating students in south-western Uganda. The students responded to a number of questions, including aspects concerning sexuality, physical and mental health, sexual risk behaviour, and experiences with drugs. The questions about homosexuality pertained to the students' emotions as well as their actions.

19 Mar 2016

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS.

18 Mar 2016

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

In a study using mice, the Johns Hopkins University School of Medicine infectious disease experts have added to evidence that statin drugs — known primarily for their cholesterol-lowering effects — can significantly reduce the time it takes to clear tuberculosis infection.

17 Mar 2016

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen.

16 Mar 2016

HIV drug could delay drug resistance, making skin cancer treatment effective for longer time

An HIV drug could stop one of the early changes in skin cancer cells that leads to them becoming resistant to treatment, according to a Cancer Research UK-funded study published in Cancer Cell today

15 Mar 2016

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

Building upon earlier research, investigators at UT Southwestern Medical Center and their collaborators have identified a new innate immunity pathway that protects mammals from viral oncogenesis, the process by which viruses cause normal cells to become cancerous.

14 Mar 2016

New microfluidic biosensor can identify white blood cells quickly for AIDS diagnosis

Researchers from the University of Illinois at Urbana-Champaign have developed a highly sensitive biosensor based on a differential immuno-capture technology that can detect sub-populations of white blood cells. As part of a small, disposable biochip, the microfluidic biosensor can count CD4+/CD8+ T cells quickly and accurately for AIDS diagnosis in the field.

14 Mar 2016

Negative cancer clinical trials have long-term impact on research

Cancer clinical trials with negative results don't make an immediate splash in the scientific literature, but they do have a long-term impact on cancer research, according to a new study by SWOG, the federally funded international clinical trials network.

11 Mar 2016

Low bone mass higher in HIV-infected males than in females

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals - assessed by sex and HIV status - to try to determine causes of this differential bone loss.

11 Mar 2016

HIV News and Research

UC San Diego Health participates in nationwide clinical study on hemophilia B gene therapy

USC's Keck School of Medicine researcher named recipient of NCI Outstanding Investigator Award

New reference guide can help HIV care providers treat chronic pain

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Antibodies given within one day of SHIV exposure can clear the virus

World TB Day 2016: WHO calls to Unite to End TB

Specialized gene editing system paves way to eventual cure for HIV patients

N-KICS tool helps describe intensity of nursing care for children with CMC

New study provides insight into HIV-dependent immune dysfunction

New ultra-sensitive technique shows promise as diagnostic tool for cancers, HIV

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

Study associates prevalence of homosexual relations in Uganda with increased health risks

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

HIV drug could delay drug resistance, making skin cancer treatment effective for longer time

Researchers find new innate immunity pathway that protects mammals from viral oncogenesis

New microfluidic biosensor can identify white blood cells quickly for AIDS diagnosis

Negative cancer clinical trials have long-term impact on research

Low bone mass higher in HIV-infected males than in females

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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