Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Lilly and Boehringer Ingelheim's Basaglar (insulin glargine injection) gets FDA's tentative approval

The U.S. Food and Drug Administration today granted tentative approval for Basaglar (insulin glargine injection), which is indicated to improve glycemic control in adults with type 2 diabetes and in combination with mealtime insulin in adults and pediatric patients with type 1 diabetes.

19 Aug 2014

Almonds can help reduce inflammation in people with poorly controlled diabetes

Evidence continues to mount supporting the role of almonds and other tree nuts as part of an overall dietary pattern that is beneficial for those with type 2 diabetes. Three new studies suggest a relationship between regular consumption of tree nuts, such as almonds, and improvement in various markers of health in type 2 diabetes.

12 Aug 2014

Acidity sensor helps to estimate dynamics of insulin production

Many human metabolic functions only run smoothly if the acid level in the body remains neutral and stable. For humans, normal blood pH values lie between 7.35 and 7.45. By way of comparison, an empty stomach is extremely acidic, with a pH value of 1.5.

12 Aug 2014

UChicago Medicine and Advocate Health Care wins NIH grant to find new ways to prevent type 1 diabetes

The University of Chicago Medicine and Advocate Children's Hospital / Advocate Health Care have received a five-year, $1.8-million grant from the National Institutes of Health to find new ways to delay and prevent type 1 diabetes. The grant will establish the first Type 1 Diabetes TrialNet Clinical Center in Chicago.

12 Aug 2014

Halozyme reports revenues of $18.4 million, net loss of $16.3 million for Q2 2014

Halozyme Therapeutics, Inc. today reported financial results for the second quarter ended June 30, 2014. Financial highlights for the second quarter include revenues of $18.4 million and a net loss of $16.3 million, or $0.13 per share.

12 Aug 2014

Sanofi, MannKind sign licensing agreement to develop and commercialize Afrezza Inhalation Powder

Sanofi and MannKind Corporation announced today that they have entered into a worldwide exclusive licensing agreement for development and commercialization of Afrezza (insulin human) Inhalation Powder, a new rapid-acting inhaled insulin therapy for adults with type 1 and type 2 diabetes.

11 Aug 2014

Inadequate management common in young-onset Type 2 diabetes

Patients with young-onset Type 2 diabetes have worse metabolic control than those with late-onset disease, but they are less likely to receive organ-protective drugs, show data from the Joint Asia Diabetes Evaluation cohort.

8 Aug 2014

Notch signaling also plays important role in onset of obesity and Type 2 diabetes

A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment.

8 Aug 2014

BD Medical announces retail pharmacy launch of BD AutoShield Duo

BD Medical, a segment of BD (Becton, Dickinson and Company), a leading global medical technology company, today announced the retail pharmacy launch of BD AutoShield Duo, the only pen needle with patented dual front and back-end shields that provides greater convenience and safety before and after injecting.

From BD (Becton, Dickinson and Company) 6 Aug 2014

Mental health coaching eases depression and reduces blood sugar levels in people with diabetes

In a rural, low-income area with a high rate of diabetes, mental health coaching significantly eased depression and reduced blood sugar levels in people with diabetes, according to a pilot study being presented here today at AADE14, the American Association of Diabetes Educators Annual Meeting & Exhibition.

6 Aug 2014

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Blood sugar surges - after-meal glucose "spikes" - can be life threatening for the 29 million Americans with diabetes. Diabetic blood sugar spikes have been linked to cardiovascular disease, cancer, Alzheimer's disease, kidney failure, and retinal damage.

5 Aug 2014

New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

Various active substances in oral antidiabetic agents are frequently combined in the treatment of diabetes in order to achieve an effective reduction in the blood sugar. A new, very promising approach combines the substances metformin and SGLT2 inhibitors, the latter were just approved in 2012.

4 Aug 2014

Metformin and SGLT2 inhibitors together reduce blood sugar levels

Metformin and SGLT2 inhibitors together reduce the blood sugar levels considerably more effectively than either drug alone.

4 Aug 2014

Findings shed light on why PPARγ activators have side effect of promoting weight gain

The brain plays a central role in regulating appetite and whole-body metabolism. A protein known as PPARγ is important in the brain's control of food intake and body weight, but the identity of the neurons regulating this process has been unclear.

4 Aug 2014

Diabetes linked to increased head and neck cancer risk

People with diabetes mellitus have a significantly increased risk of developing head and neck cancer compared with those without the condition, show results of a large study conducted in Taiwan.

1 Aug 2014

Researchers identify possible new drug target for treating childhood blood cancer

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers at NYU Langone Medical Center report that they have identified a possible new drug target for treating the disease.

1 Aug 2014

Tree nuts have positive impact on glycemic control in diabetes and on metabolic syndrome criteria

Two new meta-analyses involving tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) were recently published in the online publications, British Medical Journal Open (BMJ Open) and PLOS ONE.

1 Aug 2014

Researchers find promising technique for type 1 diabetics to restore insulin producing cells

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes-insulin-producing beta cells.

31 Jul 2014

ChromaDex to provide Murdoch Childrens Research Institute with NR ingredient for research use

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, animal health, cosmetic and pharmaceutical industries, announced today it has entered into a material transfer agreement (MTA) with Murdoch Childrens Research Institute, the preeminent child health research institute in Australia.

31 Jul 2014

GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

GSK today announced that once-weekly Tanzeum (albiglutide), a prescription injectable treatment for type 2 diabetes in adults, as an adjunct to diet and exercise, is now available in pharmacies throughout the U.S.

29 Jul 2014

Insulin News and Research

Further Reading

Lilly and Boehringer Ingelheim's Basaglar (insulin glargine injection) gets FDA's tentative approval

Almonds can help reduce inflammation in people with poorly controlled diabetes

Acidity sensor helps to estimate dynamics of insulin production

UChicago Medicine and Advocate Health Care wins NIH grant to find new ways to prevent type 1 diabetes

Halozyme reports revenues of $18.4 million, net loss of $16.3 million for Q2 2014

Sanofi, MannKind sign licensing agreement to develop and commercialize Afrezza Inhalation Powder

Inadequate management common in young-onset Type 2 diabetes

Notch signaling also plays important role in onset of obesity and Type 2 diabetes

BD Medical announces retail pharmacy launch of BD AutoShield Duo

Mental health coaching eases depression and reduces blood sugar levels in people with diabetes

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

Metformin and SGLT2 inhibitors together reduce blood sugar levels

Findings shed light on why PPARγ activators have side effect of promoting weight gain

Diabetes linked to increased head and neck cancer risk

Researchers identify possible new drug target for treating childhood blood cancer

Tree nuts have positive impact on glycemic control in diabetes and on metabolic syndrome criteria

Researchers find promising technique for type 1 diabetics to restore insulin producing cells

ChromaDex to provide Murdoch Childrens Research Institute with NR ingredient for research use

GSK announces availability of once-weekly Tanzeum in pharmacies throughout the U.S.

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