Immune System News and Research

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Could virosome-based nanovaccines be a promising new approach to preventing viral diseases?

A recent review in the International Journal of Biological Macromolecules provides a novel overview of 'virosome'-based nanovaccine production, its properties, and its application in viral diseases, emphasizing its importance in SARS-CoV-2 vaccine discovery.

20 Apr 2021

Gut's immune response in COVID-19 patients may not provide adequate protection to other organs

Our guts may not provide long-lasting systemic immunity from COVID-19, which is where immune cells circulate through the body to provide protection to other organs, finds a new study published in Frontiers in Immunology.

20 Apr 2021

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Opioid addicts wage a daily war within over whether or not to use a drug whose side effect can be death. If those same addicts, however, had the choice to take an opioid vaccine once or twice a year, their internal struggle could be over.

20 Apr 2021

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

In a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).

19 Apr 2021

COVID-19 pandemic has created major changes in delivery of MS care

A survey of U.S. multiple sclerosis, or MS, specialist clinicians reveals the COVID-19 pandemic has created major changes in how they deliver care.

19 Apr 2021

Researchers decipher the molecular underpinning of exceptional responses in glioblastoma patients

Despite access to some of the best possible medical care in the world, Senators John McCain and Edward Kennedy both died within 18 months of their diagnosis of glioblastoma, an aggressive form of brain cancer.

19 Apr 2021

One dose of mRNA vaccine may be sufficient for individuals previously infected with SARS-CoV-2

A recent scientific report from Israel shows how healthcare workers previously infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) present with higher Immunoglobulin G (IgG) titers after receiving one dose of Pfizer–BioNTech COVID-19 vaccine in comparison to their fully vaccinated, never-infected counterparts. Conversely, the occurrence of post-vaccination infection does not increase IgG titers.

19 Apr 2021

Research team identifies new factor in the development of psoriasis

Psoriasis is a common inflammatory skin condition. The underlying genetic factors have not yet been sufficiently researched.

19 Apr 2021

Study sheds new light on the ability of pancreatic cancer cells to metastasize

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death - it is the cancer's ability to evade detection and metastasize to other organs.

19 Apr 2021

New COVID-19 vaccine could provide protection against existing and future strains of coronaviruses

A COVID-19 vaccine that could provide protection against existing and future strains of the COVID-19 coronavirus, and other coronaviruses, and cost about $1 a dose has shown promising results in early animal testing.

19 Apr 2021

Researchers develop computational model to predict changes in SARS-CoV-2’s viral fitness

Two researchers from the Université Libre de Bruxelles in Belgium, Fabrizio Pucci and Marianne Rooman, recently built a simplified computational model, called SpikePro, to predict the SARS-CoV-2 fitness from the amino acid sequence and structure of the spike protein. This study focuses on the spike protein’s stability and the binding affinity to the host receptor.

19 Apr 2021

Obesity, hypertension and smoking linked to lower vaccine-induced antibody production against SARS-CoV-2

In a recent study posted to the medRxiv preprint server, a research group from Italy has demonstrated that the antibody response can be blunted in subjects with certain risk factors shortly after the second dose of mRNA vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Apr 2021

FDA revokes EUA for monoclonal antibody therapy bamlanivimab to treat patients with COVID-19

Today, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody therapy bamlanivimab, when administered alone, to be used for the treatment of mild-to-moderate COVID-19 in adults and certain pediatric patients.

17 Apr 2021

The shock and reality of catching Covid after being vaccinated

Robin Hauser, a pediatrician in Tampa, Fla., got covid in February. What separates her from the vast majority of the tens of millions of other Americans who have come down with the virus is this: She got sick seven weeks after her second dose of the Pfizer-BioNTech vaccine.

17 Apr 2021

Studies suggest mRNA COVID-19 vaccine may have reduced efficacy in patients with blood cancer

Two new studies published in Blood suggest that the mRNA COVID-19 vaccine may have reduced efficacy in individuals with chronic lymphocytic leukemia (CLL) and multiple myeloma, two types of blood cancer.

17 Apr 2021

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

17 Apr 2021

Candidate coronavirus vaccines show promising results in early animal testing

A candidate vaccine that could provide protection against the COVID-19 virus and other coronaviruses has shown promising results in early animal testing.

17 Apr 2021

Exposure to silica dust at work may increase risk of autoimmune rheumatic diseases

If you are exposed to silica (quartz) dust at work - e.g. from working with concrete and granite - you have a greater risk of certain types of rheumatic disease.

17 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

An estimated 10% to 30% of people who get Covid-19 suffer from lingering symptoms of the disease, or what’s known as “long Covid.”

16 Apr 2021

Immune System News and Research

Could virosome-based nanovaccines be a promising new approach to preventing viral diseases?

Gut's immune response in COVID-19 patients may not provide adequate protection to other organs

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

COVID-19 pandemic has created major changes in delivery of MS care

Researchers decipher the molecular underpinning of exceptional responses in glioblastoma patients

One dose of mRNA vaccine may be sufficient for individuals previously infected with SARS-CoV-2

Research team identifies new factor in the development of psoriasis

Study sheds new light on the ability of pancreatic cancer cells to metastasize

New COVID-19 vaccine could provide protection against existing and future strains of coronaviruses

Researchers develop computational model to predict changes in SARS-CoV-2’s viral fitness

Obesity, hypertension and smoking linked to lower vaccine-induced antibody production against SARS-CoV-2

FDA revokes EUA for monoclonal antibody therapy bamlanivimab to treat patients with COVID-19

The shock and reality of catching Covid after being vaccinated

Studies suggest mRNA COVID-19 vaccine may have reduced efficacy in patients with blood cancer

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Candidate coronavirus vaccines show promising results in early animal testing

Exposure to silica dust at work may increase risk of autoimmune rheumatic diseases

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

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