Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Switching off a single gene converts human gastrointestinal cells into insulin-producing cells

By switching off a single gene, scientists at Columbia University's Naomi Berrie Diabetes Center have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain cells inside a person's GI tract to produce insulin.

30 Jun 2014

Research provides new insight into effects of adding fructose to Western diet high in fat

A high-fructose, high-fat diet can cause harmful effects to the livers of adult rats, according to new research published in Experimental Physiology, providing new insight into the effects of adding fructose to a Western diet high in fat.

28 Jun 2014

Afrezza gets FDA approval to improve glycemic control in adults with diabetes mellitus

The U.S. Food and Drug Administration today approved Afrezza (insulin human) Inhalation Powder, a rapid-acting inhaled insulin to improve glycemic control in adults with diabetes mellitus. Afrezza is a rapid-acting inhaled insulin that is administered at the beginning of each meal, or within 20 minutes after starting a meal.

28 Jun 2014

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Sinai Hospital of Baltimore endocrinologist, Henry G. Fein, M.D., today presented new research showing that patients with Cushing's syndrome, a rare disease that can lead to extreme weight gain, type 2 diabetes, high blood pressure and psychological issues, experienced significant, sustained weight loss while taking oral medication daily over a number of years to manage symptoms of the disease.

25 Jun 2014

Fatty acids in nuts help reduce risk of CHD in people with type 2 diabetes

Findings from a new study published in Nutrition, Metabolism & Cardiovascular Diseases show that the fatty acids in nuts have the potential to help reduce the risk of coronary heart disease (CHD) in people with type 2 diabetes.

25 Jun 2014

Discovery provides scientists with better understanding of limiting uncontrolled cell growth

Biologists at UC San Diego have found the "missing link" in the chemical system that enables animal cells to produce ribosomes-the thousands of protein "factories" contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.

24 Jun 2014

Pilot study to evaluate advanced artificial pancreas technology under real-world situations

For several years, JDRF-funded researchers at the University of Virginia Center for Diabetes Technology have been hard at work designing an artificial pancreas system that would allow individuals with type 1 diabetes (T1D) to go about their daily lives and sleep through the night with less worry about life-threatening blood-sugar highs and lows.

24 Jun 2014

Growth hormone deficiency may protect people from developing Type 2 diabetes, cancer

People who lack growth hormone (GH) receptors also appear to have marked insulin sensitivity that prevents them from developing diabetes and lowers their risk for cancer, despite their increased percentage of body fat, new research finds.

24 Jun 2014

Mice exposed to fungicide tolyfluanid show metabolic changes

Mice exposed to the fungicide tolyfluanid (TF) showed metabolic changes similar to those that signify the development of the metabolic syndrome. The results, which were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

24 Jun 2014

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

In adults with prediabetes, a new drug that alters microbial populations and their environment in the gastrointestinal (GI) tract improves glucose tolerance-the body's response to consuming carbohydrates- after four weeks of treatment and without a change in diet.

24 Jun 2014

Adults with Type 2 diabetes achieve better blood glucose control after sleeve gastrectomy surgery

Adults with Type 2 diabetes achieve better blood glucose (sugar) control two years after undergoing laparoscopic sleeve gastrectomy than do patients who receive standard medical diabetes care without this weight loss surgery, a new study finds.

23 Jun 2014

Soy protein supplements do not reduce testosterone levels in men with Type 2 diabetes

Soy protein supplements, which contain natural estrogens, do not reduce testosterone levels in men with Type 2 diabetes who already have borderline-low testosterone, according to a new study.

23 Jun 2014

70% of adults with Type 1 diabetes never use blood glucose self-monitoring devices to download historical data

Almost 70 percent of adults with Type 1 diabetes never use their blood glucose self-monitoring devices or insulin pumps to download historical data about their blood sugar levels and insulin doses-information that likely would help them manage their disease better.

23 Jun 2014

Study explores new ways to improve medications to treat type 2 diabetes

A better understanding of how the transcription factor Peroxisome Proliferator-Activated Receptor Gamma (PPARgamma) works is critical to find new ways to improve medications to treat type 2 diabetes.

23 Jun 2014

Women who develop gestational diabetes perform worse on cognitive function tests

Women who develop diabetes during pregnancy, called gestational diabetes, perform worse on cognitive function tests than do women with a normal pregnancy, according to a new study from Turkey.

23 Jun 2014

Long-term mild cold exposure can stimulate brown fat growth

Long-term mild cold exposure can stimulate brown fat growth and activity in humans and may benefit glucose and energy metabolism, a new study finds.

23 Jun 2014

Researchers shown how free radicals contribute to fatty liver disease

An international team of scientists led by Monash University researchers has shown how free radicals contribute to type 2 diabetes, obesity and fatty liver disease.

23 Jun 2014

African American women respond differently to anti-inflammatory effect of aspirin than white women

African American women respond differently to the anti-inflammatory effect of aspirin than do white American women, new research finds.

23 Jun 2014

Greenlander study identifies single mutation with large diabetes risk

Researchers have used a Greenlandic cohort to identify a genetic mutation whose effect on the risk of diabetes is “several times larger” than any previously discovered.

20 Jun 2014

Telephone-based weight loss intervention is effective in breast cancer treatments

A series of simple telephone calls can make a profound difference in helping women to meet their treatment goals for breast cancer, according to a randomized trial of women who are also obese, published online today in Journal of Clinical Oncology by Dr. Pamela Goodwin of Mount Sinai Hospital and the Lunenfeld-Tanenbaum Research Institute.

20 Jun 2014

Insulin News and Research

Further Reading

Switching off a single gene converts human gastrointestinal cells into insulin-producing cells

Research provides new insight into effects of adding fructose to Western diet high in fat

Afrezza gets FDA approval to improve glycemic control in adults with diabetes mellitus

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Fatty acids in nuts help reduce risk of CHD in people with type 2 diabetes

Discovery provides scientists with better understanding of limiting uncontrolled cell growth

Pilot study to evaluate advanced artificial pancreas technology under real-world situations

Growth hormone deficiency may protect people from developing Type 2 diabetes, cancer

Mice exposed to fungicide tolyfluanid show metabolic changes

Researchers develop GI microbiome modulators to treat prediabetes and diabetes

Adults with Type 2 diabetes achieve better blood glucose control after sleeve gastrectomy surgery

Soy protein supplements do not reduce testosterone levels in men with Type 2 diabetes

70% of adults with Type 1 diabetes never use blood glucose self-monitoring devices to download historical data

Study explores new ways to improve medications to treat type 2 diabetes

Women who develop gestational diabetes perform worse on cognitive function tests

Long-term mild cold exposure can stimulate brown fat growth

Researchers shown how free radicals contribute to fatty liver disease

African American women respond differently to anti-inflammatory effect of aspirin than white women

Greenlander study identifies single mutation with large diabetes risk

Telephone-based weight loss intervention is effective in breast cancer treatments

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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