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Scientist receives NIH New Innovator Award to design innovative approaches for cancer treatment

Derek Taylor, PhD, a member of the Case Western Reserve School of Medicine, has been awarded the prestigious New Innovator Award by the National Institutes of Health (NIH).

22 Oct 2013

Skin cancer drug shows periocular promise

Early research suggests that patients with periocular basal cell carcinoma may benefit from treatment with a drug targeting the Hedgehog signaling pathway.

21 Oct 2013

Research paper published by Scientific Reports details the efficacy of n3D's Apple iPhone app

Joint venture partners Rainbow Coral Corp. and Nano3D Biosciences (n3D) are proud to announce that the journal Scientific Reports published the first research document detailing the efficacy of n3D's revolutionary new Apple iPhone app today.

21 Oct 2013

Verastem presents positive results from VS-6063 clinical and preclinical studies at 2013 AACR-NCI-EORTC meeting

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced positive results from the Phase 1 portion of its Phase 1/1b study of defactinib (VS-6063) in combination with paclitaxel in patients with ovarian cancer that were presented at the 2013 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston.

21 Oct 2013

UCLA study uncovers biological clock that may shed light on why our bodies age

Everyone grows older, but scientists don't really understand why. Now a UCLA study has uncovered a biological clock embedded in our genomes that may shed light on why our bodies age and how we can slow the process.

21 Oct 2013

EntreMed presents preclinical data for ENMD-2076 in triple-negative breast cancer

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, announced today the presentation of preclinical data from a study to assess the role of p53 family tumor suppressors in mediating response to ENMD-2076 in triple-negative breast cancer (TNBC).

21 Oct 2013

CSHL researchers explore how the brain integrates multiple signals to identify one unique smell

Think of the smell of an orange, a lemon, and a grapefruit. Each has strong acidic notes mixed with sweetness. And yet each fresh, bright scent is distinguishable from its relatives. These fruits smell similar because they share many chemical compounds. How, then does the brain tell them apart? How does the brain remember a complex and often overlapping chemical signature as a particular scent?

21 Oct 2013

Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

Bioengineers build novel tool to visualize protein networks from breast cancer cell data

A colorful wheel developed by Rice University bioengineers to visualize protein interactions has won an international competition for novel strategies to study the roots of breast cancer.

21 Oct 2013

New investigational drug offers potential treatment option for lung cancer

PF-06463922, an investigational drug being developed by Pfizer Inc., has the potential to become a new treatment option for patients who have lung cancer harboring abnormalities in the ALK gene, according to preclinical results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

21 Oct 2013

Inovio Pharmaceuticals begins phase I clinical trial for hepatitis C vaccine

Inovio Pharmaceuticals, Inc. announced today that the safety, tolerability and immunogenicity of its therapeutic vaccine for hepatitis C (INO-8000/VGX-6150) will be studied in a phase I clinical trial in chronically HCV infected patients.

21 Oct 2013

Cell Therapeutics presents preclinical study results of PIXUVRI at AACR-NCI-EORTC meeting

Cell Therapeutics, Inc. (CTI) today announced the presentation of findings from a preclinical study of PIXUVRI® (pixantrone) that suggest its mechanism of inducing tumor cell death is novel and distinct from that of anthracyclines such as doxorubicin.

21 Oct 2013

Scientists find that activating family of small protein could suppress liver malignancies

A team of scientists from the National University of Singapore (NUS) has found that activating a family of small protein, known as Rho, could suppress liver malignancies.

21 Oct 2013

Certain food and lifestyle habits can turn on or off expression of cancer related genes

Research performed at the Center of Research and Advanced Studies (Cinvestav) has identified that certain food and lifestyle habits can turn on or off the expression of cancer related genes.

21 Oct 2013

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

LEE011, a small-molecule inhibitor of cyclin-dependent kinases (CDK) 4/6 being developed by Novartis Oncology, showed promising results in drug-resistant melanoma and drug-resistant breast cancer when tested in combination with other targeted therapies, and based on these preclinical results, several phase I clinical trials were launched recently, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held October 19-23.

21 Oct 2013

New research identifies internal timepiece that accurately gauge age of human organs and tissues

21 Oct 2013

Scientists find unexpected molecular switch that prompts blood stem cells aging

Scientists report in Nature they have found a novel and unexpected molecular switch that could become a key to slowing some of the ravages of getting older as it prompts blood stem cells to age.

21 Oct 2013

Whitehead Institute scientists discover insidious nature of influenza virus

Revealing influenza's truly insidious nature, Whitehead Institute scientists have discovered that the virus is able to infect its host by first killing off the cells of the immune system that are actually best equipped to neutralize the virus.

21 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Researchers identify key therapeutic target for cancers driven by KRAS protein

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

20 Oct 2013

Cell News and Research

Scientist receives NIH New Innovator Award to design innovative approaches for cancer treatment

Skin cancer drug shows periocular promise

Research paper published by Scientific Reports details the efficacy of n3D's Apple iPhone app

Verastem presents positive results from VS-6063 clinical and preclinical studies at 2013 AACR-NCI-EORTC meeting

UCLA study uncovers biological clock that may shed light on why our bodies age

EntreMed presents preclinical data for ENMD-2076 in triple-negative breast cancer

CSHL researchers explore how the brain integrates multiple signals to identify one unique smell

Discovery sheds light on how forces outside of cells get translated into internal signals

Bioengineers build novel tool to visualize protein networks from breast cancer cell data

New investigational drug offers potential treatment option for lung cancer

Inovio Pharmaceuticals begins phase I clinical trial for hepatitis C vaccine

Cell Therapeutics presents preclinical study results of PIXUVRI at AACR-NCI-EORTC meeting

Scientists find that activating family of small protein could suppress liver malignancies

Certain food and lifestyle habits can turn on or off expression of cancer related genes

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

New research identifies internal timepiece that accurately gauge age of human organs and tissues

Scientists find unexpected molecular switch that prompts blood stem cells aging

Whitehead Institute scientists discover insidious nature of influenza virus

Clarified role of signal-relay proteins may help explain spread of cancer

Researchers identify key therapeutic target for cancers driven by KRAS protein

How to optimize your cell line development eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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