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Intestinal cells can change specializations during their lives, finds study

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

1 Mar 2022

Research sheds light on the role of lipids in Alzheimer’s disease development

Neurons in the brain coexist with and rely on many other cell types to function properly. Astrocytes, which take their name from their star shape, ensure the survival of neurons by feeding and detoxifying them with the help of a multifunctional protein, APOE.

1 Mar 2022

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

Researchers at Massachusetts General Hospital, in partnership with NYU Langone Health, have launched a multi-center clinical trial to investigate a new treatment for pediatric type 1 diabetes even in subjects with established disease.

1 Mar 2022

Vapers, hookah smokers may expose the nose and sinuses to more emissions than cigarette smokers

People who smoke e-cigarette and hookah are more than twice as likely to exhale particles through their nose compared with people who smoke cigarettes, who favor exhaling the emissions from their mouth, a new study shows.

1 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

In a new study, researchers performed genomic sequencing of SARS-CoV-2-infected samples and aimed to identify the dominant variant, assess the mutation profile, and determine the sample-to-sequence turnover time.

1 Mar 2022

Effectiveness of Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing severe SARS-CoV-2 infection

A new study compared the effectiveness of the Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing SARS-CoV-2 infections.

1 Mar 2022

Scientists discover an innate form of immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa.

28 Feb 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Researchers report a new, more efficient way to grow breast cancer models

For years, researchers at Huntsman Cancer Institute at the University of Utah have honed a process of developing breast cancer models using tumors donated by breast cancer patients, which they then implant into mice as a way to study the tumor's behavior.

28 Feb 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy-; even if not used during pregnancy itself-; could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Distributed lag models to estimate incident rates using concentrations of SARS-CoV-2 RNA from wastewater solids

The team analyzed the effect of sampling frequency on the prediction error of IRs by using reduced sampling across different sewer sheds of varying sizes and features.

28 Feb 2022

Studying coagulopathy in COVID-19

A new study published in the journal Diagnostics provided an overview of ROTEM with a particular focus on interpreting the symmetrical clot formation curve. Researchers also introduced new parameters that could aid in distinguishing between COVID-19 patients and outcomes.

28 Feb 2022

New dialysis system shows ability to make sterile, medical grade water at the point-of-care

Findings from preliminary tests of a new dialysis system have confirmed its ability to make sterile, medical grade water to provide an affordable, accessible home-based treatment option for patients with kidney failure.

27 Feb 2022

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Peanut allergies are hard to treat and can cause fatal or near-fatal anaphylactic reactions. People usually don't outgrow peanut allergy, requiring lifelong scrutiny of food labels to avoid even small traces of peanut.

27 Feb 2022

Targeting a specific protein can help prevent or delay prostate cancer progression

Targeting a specific protein that is often overexpressed in prostate cancer can help prevent or delay the disease from spreading to other parts of the body, according to a study led by Cedars-Sinai Cancer investigators.

25 Feb 2022

Non-invasive ultrasonography to evaluate gonad reproductive condition in abalones

The world's abalone are threatened, endangered or otherwise vulnerable in nearly every corner of the planet. While captive breeding efforts are underway for some species, these giant sea snails are notoriously difficult to spawn.

25 Feb 2022

Maladaptive coping strategies may contribute to decreased sleep quality

Most patients with sleep problems adopt maladaptive coping strategies – such as taking sleep aids, using caffeine, and taking daytime naps – that may actually contribute to decreased sleep quality, reports a study in The Nurse Practitioner.

25 Feb 2022

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Novocure announced that a new study published in the Journal of Clinical Investigation (JCI) finds treatment with Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response that may be effectively used together with existing immunotherapy approaches in the treatment of solid tumors, with limited systemic toxicity.

25 Feb 2022

Laboratory News and Research

Intestinal cells can change specializations during their lives, finds study

Research sheds light on the role of lipids in Alzheimer’s disease development

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

Vapers, hookah smokers may expose the nose and sinuses to more emissions than cigarette smokers

AI and machine learning could improve cancer diagnosis through biomarker discovery

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

Effectiveness of Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing severe SARS-CoV-2 infection

Scientists discover an innate form of immunological memory in the intestine

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

Researchers report a new, more efficient way to grow breast cancer models

Research shows intergenerational effects of preconception opioids in male offspring rats

Distributed lag models to estimate incident rates using concentrations of SARS-CoV-2 RNA from wastewater solids

Studying coagulopathy in COVID-19

New dialysis system shows ability to make sterile, medical grade water at the point-of-care

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Targeting a specific protein can help prevent or delay prostate cancer progression

Non-invasive ultrasonography to evaluate gonad reproductive condition in abalones

Maladaptive coping strategies may contribute to decreased sleep quality

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

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