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Medicare beneficiaries can switch their coverage during open enrollment, says Allsup

Medicare annual enrollment ended Dec. 31, but some beneficiaries can switch their coverage during open enrollment from Jan. 1 to March 31, according to Allsup, a nationwide provider of Social Security disability representation and Medicare services.

6 Jan 2010

International Headache Society publishes new guidelines to stimulate more research on headache treatment

If you're one of the millions of headache sufferers around the world, more effective relief might be on the way in years to come. That's because the International Headache Society has just published new research guidelines intended to stimulate more research into headache treatment, and to provide researchers with guidelines to cut health risks associated with treatment.

6 Jan 2010

Treatment with Effient more cost effective, show TRITON-TIMI 38 clinical trial results

Results from a health economic substudy of the TRITON-TIMI 38 clinical trial showed that among patients with acute coronary syndromes (ACS) managed with percutaneous coronary intervention (PCI), including stenting, treatment with Effient(®) (prasugrel) compared with branded clopidogrel (Plavix(®)) was more cost effective, and in most cases cost saving.

6 Jan 2010

Findings open up significant possibilities for developing micro-screening devices for drug discovery

A Nobel-winning process for testing new drugs to treat diseases such as Huntington's, Parkinson's, and muscular dystrophy is getting an electrical charge.

6 Jan 2010

New research shows breast milk is not as important for mother or child's health

Feeling guilty that you didn't breastfeed your children enough - or at all? Relax. New research shows that breast milk is not as important for either the mother or the child's health.

6 Jan 2010

Data from national surveys shows few Americans receive consistent treatment for MDD

Only about half of Americans diagnosed with major depression in a given year receive treatment for it and even fewer - about one-fifth - receive treatment consistent with current practice guidelines, according to data from national surveys supported by the National Institute of Mental Health of the National Institutes of Health.

6 Jan 2010

Historic low in drug spending growth coincides with cost-saving tools developed by PBMs

Expenditures on prescription drugs increased just 3.2 percent in 2008 – the smallest annual rate of increase in 47 years – according to new data released today by the Centers for Medicare and Medicaid Services (CMS).

6 Jan 2010

New survival prediction equation may impact clinical trials for treating PAH

Setting out to determine the survival of patients with pulmonary arterial hypertension (PAH), researchers at the University of Chicago Medical Center and their colleagues also discovered that an equation used for more than 20 years to predict survival is outdated.

6 Jan 2010

Patient enrolled in Phase I clinical study of two investigational compounds: MK-2206 and AZD6244

Dr. Anthony Tolcher, clinical director for South Texas Accelerated Research Therapeutics (START) at the START Center for Cancer Care in San Antonio, announced today that the first patient has been enrolled in a groundbreaking Phase I clinical trial of a novel combination anticancer regimen composed of two investigational compounds: MK-2206 from Merck & Co., Inc. and AZD6244 (ARRY-886*) from AstraZeneca.

6 Jan 2010

Keryx Biopharmaceuticals reaches SPA agreement for Phase 3 clinical program for Zerenex

Keryx Biopharmaceuticals, Inc. announced today that it has reached agreement with the U.S. Food and Drug Administration (FDA) regarding a Special Protocol Assessment (SPA) on the design of a Phase 3 clinical program for Zerenex(TM) (ferric citrate), its iron-based phosphate binder for the treatment of elevated serum phosphorous levels, or hyperphosphatemia, in patients with end-stage renal disease (ESRD).

6 Jan 2010

Opinions: U.S. medical emergency response; micronutrients; rotavirus vaccine; antibiotic development

"[D]espite the tireless efforts of public health and health-care workers, America's experience with H1N1 shows that the nation is not prepared to deal with a flu pandemic," former Democratic Senator Bob Graham and former Republican Senator Jim Talent write in Washington Post opinion piece that examines U.S. preparedness for medical emergencies. The writers chaired the Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism.

6 Jan 2010

Phase I clinical trial for Intellikine's INK128 inhibitor initiated

Intellikine, Inc. has initiated a Phase I clinical trial for its targeted anticancer drug INK128, a novel orally-available small molecule inhibitor of both the TORC1 and TORC2 complexes, key components of the PI3K/mTOR signaling pathway.

6 Jan 2010

Scott & White's CRI launches two clinical trials targeting cancers

Scott & White's Cancer Research Institute (CRI) has launched two clinical trials targeting cancers that affect both adults and children.

6 Jan 2010

Animal experiments show old antidepressant may reverse heart failure

A team of Johns Hopkins and other researchers have found in animal experiments that an antidepressant developed over 40 years ago can blunt and even reverse the muscle enlargement and weakened pumping function associated with heart failure.

6 Jan 2010

New research may yield more effective treatment for childhood leukemia

A team of Israeli scientists at the Sheba Medical Center's Research Center for Leukemia and Childhood Malignancies has discovered a method for developing a more effective and less perilous treatment for those suffering from childhood leukemia, the most common cancer in children.

6 Jan 2010

EnVivo Pharmaceuticals announces initiation and dosing of patients in Phase 2b study of EVP-6124

EnVivo Pharmaceuticals today announced the initiation and dosing of patients in a Phase 2b study of its EVP-6124 compound, a selective alpha-7 nicotinic agonist in patients with schizophrenia. EnVivo is conducting the multi-center, dose ranging, placebo controlled, three-month study in the U.S. and Europe.

6 Jan 2010

Preclinical data of Geron's telomerase inhibitor drug published

Geron Corporation today announced the publication of preclinical data demonstrating that its telomerase inhibitor drug, imetelstat (GRN163L), inhibited telomerase activity and reduced tumor size in xenograft models of glioblastoma, and inhibited the activity of glioblastoma stem cells in culture.

6 Jan 2010

Cancer Research UK and CRT to undertake phase I clinical trial of DI-B4

CANCER RESEARCH UK and Cancer Research Technology (CRT), the charity's development and commercialisation arm, are to undertake a phase I clinical trial of an investigational monoclonal antibody1 drug from Merck KGaA, Darmstadt, Germany, called DI-B4 - it is announced today (Monday).

6 Jan 2010

Most of world's 13m preterm births occur in Africa, Asia

The "vast majority" of the world's 13 million preterm births each year occur in developing countries where the babies' "chances of survivals are low," according to an article published Monday in the January issue of the Bulletin of the World Health Organization, Reuters reports.

6 Jan 2010

Findings reveals 'limpet-like' proteins can play a key role in DNA repair

UK scientists have found that a crafty family of 'limpet-like' proteins can play a crucial role in repairing DNA damage - according to two research papers published in Nature today (Wednesday). These findings could pave the way to the design of new anti-cancer drugs which target this process.

6 Jan 2010

Drugs News and Research

Medicare beneficiaries can switch their coverage during open enrollment, says Allsup

International Headache Society publishes new guidelines to stimulate more research on headache treatment

Treatment with Effient more cost effective, show TRITON-TIMI 38 clinical trial results

Findings open up significant possibilities for developing micro-screening devices for drug discovery

New research shows breast milk is not as important for mother or child's health

Data from national surveys shows few Americans receive consistent treatment for MDD

Historic low in drug spending growth coincides with cost-saving tools developed by PBMs

New survival prediction equation may impact clinical trials for treating PAH

Patient enrolled in Phase I clinical study of two investigational compounds: MK-2206 and AZD6244

Keryx Biopharmaceuticals reaches SPA agreement for Phase 3 clinical program for Zerenex

Opinions: U.S. medical emergency response; micronutrients; rotavirus vaccine; antibiotic development

Phase I clinical trial for Intellikine's INK128 inhibitor initiated

Scott & White's CRI launches two clinical trials targeting cancers

Animal experiments show old antidepressant may reverse heart failure

New research may yield more effective treatment for childhood leukemia

EnVivo Pharmaceuticals announces initiation and dosing of patients in Phase 2b study of EVP-6124

Preclinical data of Geron's telomerase inhibitor drug published

Cancer Research UK and CRT to undertake phase I clinical trial of DI-B4

Most of world's 13m preterm births occur in Africa, Asia

Findings reveals 'limpet-like' proteins can play a key role in DNA repair

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