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Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.

27 Apr 2024

Blood test predicts knee osteoarthritis eight years before tell-tale signs of the disease

A blood test successfully predicted knee osteoarthritis at least eight years before tell-tale signs of the disease appeared on x-rays, Duke Health researchers report.

26 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April)

25 Apr 2024

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases.

25 Apr 2024

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Research reveals undertreatment of women with heart disease

Women with heart disease are less often treated with cholesterol-lowering drugs than men, according to research presented today at ESC Preventive Cardiology 2024, a scientific congress of the European Society of Cardiology (ESC).

25 Apr 2024

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

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Drugs News and Research

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Blood test predicts knee osteoarthritis eight years before tell-tale signs of the disease

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Study: Antibiotic use in moderate COVID-19 linked to clinical deterioration

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

Medicare warning letters effectively cut antipsychotic prescribing for dementia patients

MIT study reveals circadian impact on drug metabolism in engineered livers

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Research reveals undertreatment of women with heart disease

Researchers identify a ‘gene module’ involved in both depression and cardiovascular disease

New system personalizes chemotherapy doses for cancer patients

Study links acid-reducing drugs to increased risk of migraine

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Anesthetic midazolam boosts survival after cardiac arrest

Younger adults with atrial fibrillation face higher rates of heart failure and stroke

Research highlights best window for paxlovid administration in COVID-19 patients

U-M scientists develop new tool to better understand neuronal signaling

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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