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Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

A personal cancer treatment vaccine that targets distinctive "neoantigens" on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

5 Jul 2017

UC scientists develop new computerized tool to promote shared decision-making with CF patients

Physician-researchers at the University of Cincinnati have developed a computerized decision-making model to promote shared decision-making with cystic fibrosis patients.

4 Jul 2017

Combination treatment could be more effective against common infection

The common and highly resistant Pseudomonas aeruginosa bacterium is a fatal threat to weakened and ill patients.

4 Jul 2017

Novel technique to monitor nerve function could transform the way doctors perform surgeries

In a first-of-its-kind study, Mount Sinai researchers have discovered a novel technique to monitor laryngeal and vagus nerve function while patients are under anesthesia during otolaryngology and neurosurgery procedures.

3 Jul 2017

New antiviral drug candidate effective against broad range of coronaviruses

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

29 Jun 2017

New lab-on-a chip predicts preterm birth risk

Preterm birth is the leading cause of neonatal morbidity and mortality. Among the many underlying causes of pregnancy-associated complications, it is known that infection and inflammation are highly significant risk factors.

29 Jun 2017

U.S. air pollution may be shortening lifespan finds new study

A new study shows that air pollution at levels below the National Ambient Air Quality Standards (NAAQS) could cut short life spans. This was one of the largest air pollution studies with more than a whopping 60 million senior citizens participating. The study was published in the Thursday’s edition of the journal New England Journal of Medicine.

28 Jun 2017

Engineers take closer look at mechanical and chemical attributes of heart defect

Elastin and collagen serve as the body's building blocks. They provide tensile strength and elasticity for a number of organs, muscles and tissues. Any genetic mutation short-circuiting their function can have a devastating, and often lethal, health impact.

28 Jun 2017

Researchers investigate how cystic fibrosis alters structure of mucus in airways

Mucus is important for maintaining healthy lungs. Inhaled particles, including bacteria and viruses, get trapped in mucus and then cilia -- tiny hair like projections on the surface of the airway cells -- sweep the mucus out of the airway.

28 Jun 2017

Researchers use new self-expanding foams for filling and sealing pleural cavities

Researchers from the University of Alicante Adhesion and Adhesive Lab and the Thorax Surgery Service from the Albacete University Hospital Complex have developed a new method for filling and sealing pleural cavities.

28 Jun 2017

Clinical trial of immunotherapy shows promising results for patients with melanoma brain tumors

Two years ago, when Kathy Roberts was 54, she started having pain in her ankle. She ignored it. Then it became swollen, and she had more and more trouble walking. So she went to a series of doctors trying to figure out the problem.

27 Jun 2017

Newly discovered antibiotic could help treat drug-resistant tuberculosis

A newly discovered antibiotic, produced by bacteria from a cystic fibrosis patient, could be used to treat cases of drug-resistant tuberculosis (TB). This is the finding of a team of scientists from Cardiff University’s School of Biosciences and the University of Warwick.

24 Jun 2017

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

A subgroup of patients with osteosarcoma - a form of bone cancer - could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators at University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

23 Jun 2017

Survivors of childhood diseases struggle to find care as adults

Rachael Goldring was born with congenital heart disease. Had she been born a few decades earlier, she probably would have died as a baby. Now 24, Goldring is part of a population of patients who present new challenges to a health care system unaccustomed to dealing with survivors of once-fatal conditions.

22 Jun 2017

UCLA-led study reveals possibility of CMV and HIV transmission from mothers to infants

HIV-positive women with cytomegalovirus, or CMV, in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV, the virus that causes AIDS, to their infants, according to a UCLA-led study.

22 Jun 2017

Scientists discover biological fingerprint in children with tuberculosis meningitis

Children with tuberculosis meningitis - a brain and spinal cord infection that leads to disability and death -- have a biological fingerprint that can be used to assess the severity of the condition, help decide the best course of treatment, and provide clues for novel treatments, scientists at the Francis Crick Institute, Imperial College London and the University of Cape Town reveal.

21 Jun 2017

The new war on sepsis

Dawn Nagel, a nurse at St. Joseph Hospital in Orange, Calif., knew she was going to have a busy day, with more than a dozen patients showing signs of sepsis.

21 Jun 2017

Could a blood test predict how cancer spreads in children?

Traditionally, we use biopsies to try to predict how cancer spreads. There are a number of molecular markers that are used, but biopsy is a limited approach. Now, the current trend is to use liquid biopsy, which is basically a blood sample.

21 Jun 2017

Lungs of highly active older adults remain strong during physical activity

Highly active older adults experience no limitations in the lungs' capacity to exchange gases (lung-diffusing capacity) during physical activity, researchers have found. The study is published in the Journal of Applied Physiology.

20 Jun 2017

Steaming freshwater fish reduces presence of cyanotoxins, study shows

A group of researchers from the Area of Toxicology in the Department of Nutrition and Bromatology. Toxicology and Legal Medicine at the University of Seville has published a globally pioneering study that shows that steaming freshwater fish for more than two minutes reduces the presence of cylindrospermopsin, a cyanotoxin, by up to 26%. However, if boiled, the reduction is smaller, 18%, with the corresponding increase in risk for the consumer.

20 Jun 2017

Lungs News and Research

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

UC scientists develop new computerized tool to promote shared decision-making with CF patients

Combination treatment could be more effective against common infection

Novel technique to monitor nerve function could transform the way doctors perform surgeries

New antiviral drug candidate effective against broad range of coronaviruses

New lab-on-a chip predicts preterm birth risk

U.S. air pollution may be shortening lifespan finds new study

Engineers take closer look at mechanical and chemical attributes of heart defect

Researchers investigate how cystic fibrosis alters structure of mucus in airways

Researchers use new self-expanding foams for filling and sealing pleural cavities

Clinical trial of immunotherapy shows promising results for patients with melanoma brain tumors

Newly discovered antibiotic could help treat drug-resistant tuberculosis

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Survivors of childhood diseases struggle to find care as adults

UCLA-led study reveals possibility of CMV and HIV transmission from mothers to infants

Scientists discover biological fingerprint in children with tuberculosis meningitis

The new war on sepsis

Could a blood test predict how cancer spreads in children?

Lungs of highly active older adults remain strong during physical activity

Steaming freshwater fish reduces presence of cyanotoxins, study shows

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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