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Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors (β-ARs).

14 Feb 2022

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Researchers reported the development and validation of a two-reaction multiplex reverse transcription-quantitative polymerase chain reaction genotyping strategy that distinguishes SARS-CoV-2 variants of concern.

14 Feb 2022

Researchers identify a powerful combination of antivirals to treat COVID-19

Researchers at the University of Maryland School of Medicine and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19.

14 Feb 2022

What does the Future of Artificial Intelligence Look Like within the Life Sciences?

In this interview, we speak to Toby Blackburn, the head of Business Development and Strategy at Emerald Cloud Lab, about the future of AI within the life science industry.

From Society for Laboratory Automation and Screening (SLAS) 14 Feb 2022

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

A new study provided the structural basis for a robust interaction between the receptor-binding domain of the SARS-CoV-2 Omicron spike protein and mouse ACE2.

13 Feb 2022

Researchers shows how ΔNp63 protein contributes to lung cancer development

Lung cancer is the second most common cancer in the U.S. and the No. 1 cause of cancer related death. Despite considerable progress in treatment options, most lung cancer patients have extremely poor outcomes with an average five-year survival rate of 21.7%.

12 Feb 2022

New fellowship aims to prepare future flight surgeons to deal with medical challenges in space

A newly launched UCLA Space Medicine Fellowship, the first of its kind in the U.S., aims to develop the next generation of flight surgeons who will support the health, safety, and well-being of human space flight and planetary expeditions.

12 Feb 2022

Performance of SARS-CoV-2 antibodies improves only after previous infection, not vaccination

New research to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) shows that, although over time the number of SARS-CoV-2 antibodies falls in both previously infected and vaccinated patients, the performance of antibodies improves only after previous infection (and not vaccination).

11 Feb 2022

Molecular cage helps researchers to get atomic-level details of key cancer protein

Acute myeloid leukemia (AML), the American Cancer Institute estimates, will affect more than 20,000 Americans this year and kill more than 11,000 of them.

11 Feb 2022

New blood-clotting test uses only a single drop of blood and smartphone

Blood clots form naturally as a way to stop bleeding when someone is injured. But blood clots in patients with medical issues, such as mechanical heart valves or other heart conditions, can lead to a stroke or heart attack.

11 Feb 2022

High mortality associated with acute kidney injury increases the urgency for new treatments

One in four patients who developed a serious complication called acute kidney injury (AKI) in the hospital will die within one year, heightening the urgency for new treatment options to improve patients' survival, according to a Henry Ford Health System study.

11 Feb 2022

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

A survey demonstrated that patients with systemic autoimmune rheumatic diseases commonly experience augmented disease severity and disrupted treatment regimens of disease-modifying antirheumatic drugs after acute COVID-19 course.

11 Feb 2022

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear.

11 Feb 2022

New protocol for transplanting 3D cellular structures to regenerate damaged intestinal tissue

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum.

10 Feb 2022

Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, according to a new study published in JAMA Internal Medicine.

10 Feb 2022

ISU surveillance efforts uncover invasive mosquito species in three Iowa counties

Iowans might notice some new uninvited guests crashing their summer barbecues this year.

10 Feb 2022

Nine new Discovery Grants awarded to fuel the development of ALS treatments

With promising new therapies for amyotrophic lateral sclerosis (ALS) on the horizon, now is the time for ongoing investment in research discovery that will continue to fuel the development of treatments.

10 Feb 2022

Regular surveillance testing of a community can prevent Covid-19 outbreaks

Covid-19 is often asymptomatic and can lead infected individuals to spread the disease without knowing it. Yet, regular surveillance testing of a community can catch these cases and prevent outbreaks.

10 Feb 2022

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.

9 Feb 2022

New cloud-based repository creates a digital fingerprint of engineered microorganisms

A cloud-based repository that creates a digital fingerprint of engineered microorganisms has been successfully trialed.

9 Feb 2022

Laboratory News and Research

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Researchers identify a powerful combination of antivirals to treat COVID-19

What does the Future of Artificial Intelligence Look Like within the Life Sciences?

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

Researchers shows how ΔNp63 protein contributes to lung cancer development

New fellowship aims to prepare future flight surgeons to deal with medical challenges in space

Performance of SARS-CoV-2 antibodies improves only after previous infection, not vaccination

Molecular cage helps researchers to get atomic-level details of key cancer protein

New blood-clotting test uses only a single drop of blood and smartphone

High mortality associated with acute kidney injury increases the urgency for new treatments

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

New protocol for transplanting 3D cellular structures to regenerate damaged intestinal tissue

Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

ISU surveillance efforts uncover invasive mosquito species in three Iowa counties

Nine new Discovery Grants awarded to fuel the development of ALS treatments

Regular surveillance testing of a community can prevent Covid-19 outbreaks

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

New cloud-based repository creates a digital fingerprint of engineered microorganisms

Lab Diagnostics and Automation - Second Edition eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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