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HSS’ doctor performs first total wrist replacement surgery with KinematX implant

Sixty-nine-year-old Mark Eisen says he waited seven years for a surgery he hopes will change his life. Last week, he had the first total wrist replacement with KinematX™, a new implant co-designed by Scott Wolfe, MD, chief emeritus of the Hand and Upper Extremity Service at Hospital for Special Surgery (HSS). Dr. Wolfe performed the surgery on April 15.

21 Apr 2021

Simple dietary supplement ameliorates schizophrenic traits in mice

A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia.

19 Apr 2021

Researchers investigate whether muscle pump action systematically changes with age

Chronic lower-limb edema (CLE) -- the permanent accumulation of fluid in the leg -- often occurs in elderly people.

19 Apr 2021

Markers of fear recall differ between sexes, but in a hormone-dependent manner

A new study shows that markers of fear recall differ between men and women, but in a hormone-dependent manner.

16 Apr 2021

Greater intake of red and processed meat associated with worse heart function, finds study

An observational study in nearly 20,000 individuals has found that greater intake of red and processed meat is associated with worse heart function.

15 Apr 2021

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease.

15 Apr 2021

Study shows how signal propagation circuit is modulated by attention

To effectively perform any daily task, the human brain needs to process information from the outside world using various cognitive functions. This cognitive processing passes through a dense interconnected network of cells whose physiology is specialized.

8 Apr 2021

Events of 2020 moved medical students to political activism

Inam Sakinah and her classmates will forever be known as the students who started medical school during the 2020 Covid-19 pandemic.

7 Apr 2021

Study shows how leptin suppresses appetite

Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain.

7 Apr 2021

UCI receives $4.2 million grant to study sporadic inclusion body myositis affecting aging adults

The National Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded UCI a 5-year, $4.2 million grant to study sporadic inclusion body myositis (sIBM), which affects aging adults causing asymmetric muscle weakness and severe disability. The disease is currently untreatable and poorly understood.

6 Apr 2021

Researchers generate a precise map of basal ganglia connectivity

Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium.

5 Apr 2021

Stay-at-home measures may have offered protective effects for youth mental health early in the pandemic

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that middle schoolers from a predominantly Latinx community, with elevated levels of mental health problems, showed a reduction in symptoms during the early stages of the pandemic.

3 Apr 2021

UCI-led team to address health impacts of adverse childhood experiences using precision medicine

A collaborative team centered in the University of California, Irvine and including Children's Hospital Orange County and Chapman University has been awarded a three-year grant totaling in excess of $2.3 million, to address the health impacts of adverse childhood experiences using precision medicine.

1 Apr 2021

Objectives, challenges and opportunities of new IASLC Molecular Database Project

A new Molecular Database Project initiated by the International Association for the Study of Lung will accelerate the understanding of lung cancer biology, clinical care and care delivery on a global scale and will improve the prognosis and optimal treatment of lung cancer across time and space, according to an editorial in the Journal of Thoracic Oncology, an official journal of the IASLC.

31 Mar 2021

Researchers provide experimental evidence for synaptic plasticity in the human brain

Neuroscientists agree that a person's brain is constantly changing, rewiring itself and adapting to environmental stimuli.

31 Mar 2021

Researchers make a breakthrough in the quest for an AMD cure

Age-related macular degeneration (AMD), which leads to a loss of central vision, is the most frequent cause of blindness in adults 50 years of age or older, affecting an estimated 196 million people worldwide. There is no cure, though treatment can slow the onset and preserve some vision.

29 Mar 2021

New study provides the most comprehensive reviews of advancements in contact lenses

A newly-published paper represents one of the most comprehensive reviews of advancements to come in contact lenses, catapulting the commonly-used medical device to applications well beyond refractive error correction.

29 Mar 2021

Study uncovers new biomarkers in patients with malignant melanoma

A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant melanoma.

25 Mar 2021

Anabolic-androgenic steroids can have deleterious effects on the brain

Anabolic-androgenic steroids (AAS), a synthetic version of the male sex hormone testosterone, are sometimes used as a medical treatment for hormone imbalance. But the vast majority of AAS is used to enhance athletic performance or build muscle because when paired with strength training.