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SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

Huge multi-omic data analysis deciphers colorectal cancer genetics

An analysis of more than 100,000 colorectal cancer cases and 154,000 healthy controls published in Nature Genetics uncovered hundreds of signals that may serve as new treatment and prevention targets.

21 Dec 2022

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

An experimental therapy showed promise as treatment for an aggressively spreading type of colorectal cancer in preclinical models, according to a new study by Weill Cornell Medicine investigators.

16 Dec 2022

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

In this interview, Yantao Li and Zhe Wang, Director of Cancer Early Screening Products and the Product Director of Oncology at BGI Genomics, talks to NewsMedical about colorectal cancer (CRC), including why incidences are important and the importance of screening.

From BGI Genomics 6 Dec 2022

Does irritable bowel syndrome result from gravity?

New research discussed the hypothesis that irritable bowel syndrome (IBS) may result from gravity.

5 Dec 2022

How two structurally different lemon pectins modulate the gut microbiota

A diet containing fruits and vegetables contains pectins (plant polysaccharides). Pectin cannot be metabolized by mammalian cells in the gastrointestinal tract but is fermented by the gut microbiota in the colon, where short-chain fatty acids (SCFAs) are released. Previous studies have examined pectin's prebiotic properties.

4 Dec 2022

Sharp increase in B cell population can prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing.

2 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

The importance of early cancer screening

In this interview, Thomas Qiu, Senior Product Manager from BGI Genomics, talks to NewsMedical about current global cancer rates, and the importance of early cancer screening.

From BGI Genomics 1 Dec 2022

Racial disparities in lung cancer start with research

During a routine visit to the Good Samaritan Clinic in Morganton, North Carolina, in 2018, Herbert Buff casually mentioned that he sometimes had trouble breathing.

30 Nov 2022

Researchers explore gut microbiome dysbiosis in acute COVID-19 infection and recovery

Researchers assessed the taxonomic characteristics of the intestinal (gut) microbiome in patients with active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

30 Nov 2022

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Recently, scientists reviewed the role of sulforaphane from cruciferous vegetables (e.g., broccoli) in preventing IBD by regulating inflammation and altering the gut microbiome.

29 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Researchers explore the anti-acne, antioxidant, and anti-inflammatory properties of Stingless bee (Tetragonula biroi)-derived propolis.

29 Nov 2022

Blood tests may be able to guide treatment discussions for patients with metastatic cancer

As cancers grow and potentially spread to new parts of the body, they often shed cells and DNA into the blood stream. DNA can be analyzed for both the amount of DNA present and whether any potential mutations exist that may aid providers in deciding on treatments.

29 Nov 2022

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

In an intensive look at the effects of the virus causing COVID-19 on patients' microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.

28 Nov 2022

Should older seniors risk major surgery? New research offers guidance

Nearly 1 in 7 older adults die within a year of undergoing major surgery, according to an important new study that sheds much-needed light on the risks seniors face when having invasive procedures.

28 Nov 2022

Novel cancer-fighting nanoparticles co-deliver a chemotherapy drug and immunotherapy

University of Pittsburgh researchers have designed cancer-fighting nanoparticles that co-deliver a chemotherapy drug and a novel immunotherapy, according to a new Nature Nanotechnology study published today.

24 Nov 2022

Fungi detected in 35 cancer types, often intracellular

In a recent article published in the journal Cell, researchers found fungal deoxyribonucleic acid (DNA) and cells at low abundances across many human cancers, with cancer type-dependent variations in fungus community composition and fungal-bacteriome interactions.

22 Nov 2022

Beetroot juice appears to affect gut microbiome, positively impacting intestinal and systemic health

In a recent study published in the Food Chemistry journal, researchers investigated the impact of consuming red beetroot juice for two weeks on gut microbiota.

21 Nov 2022

Colon News and Research

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Huge multi-omic data analysis deciphers colorectal cancer genetics

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

Does irritable bowel syndrome result from gravity?

How two structurally different lemon pectins modulate the gut microbiota

Sharp increase in B cell population can prevent intestinal healing

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

The importance of early cancer screening

Racial disparities in lung cancer start with research

Researchers explore gut microbiome dysbiosis in acute COVID-19 infection and recovery

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Blood tests may be able to guide treatment discussions for patients with metastatic cancer

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

Should older seniors risk major surgery? New research offers guidance

Novel cancer-fighting nanoparticles co-deliver a chemotherapy drug and immunotherapy

Fungi detected in 35 cancer types, often intracellular

Beetroot juice appears to affect gut microbiome, positively impacting intestinal and systemic health

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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