Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Trials, and a few unexpected triumphs, for insurance exchanges

A procurement document posted on a federal website gives the newest Obamacare contractor until mid-March to build the back end of healthcare.gov, predicting dire consequences if the work is not completed on time. Other media outlets report exchange developments from Maryland, Massachusetts, Missouri, North Carolina, Oregon, Wisconsin, Georgia and Minnesota.

22 Jan 2014

Novo Nordisk launches insulin delivery device NovoPen Echo in the U.S.

Novo Nordisk, a world leader in diabetes care, today announced the launch of the insulin delivery device NovoPen Echo in the United States. This is the first and only pen device available in the U.S. with half-unit dosing and a memory function that records the dose and time passed since the last injection.

From Novo Nordisk 21 Jan 2014

Home blood pressure best guide to metabolic risk

Home blood pressure is a good guide to which patients are likely to have the metabolic syndrome, say researchers.

20 Jan 2014

Eating high levels of flavonoids found in berries, tea, and chocolate offer protection from type 2 diabetes

Eating high levels of flavonoids including anthocyanins and other compounds (found in berries, tea, and chocolate) could offer protection from type 2 diabetes - according to research from the University of East Anglia (UEA) and King's College London.

20 Jan 2014

U of T researchers find no evidence to support 'blood-type' diet theory

Researchers from the University of Toronto have found that the theory behind the popular blood type diet--which claims an individual's nutritional needs vary by blood type--is not valid. The findings are published this week in PLoS One.

17 Jan 2014

Researchers managed to replicate human pancreatic beta cells in mouse model

Klaus Kaestner, PhD, professor of Genetics and postdoctoral fellow Dana Avrahami, PhD, from the Perelman School of Medicine, University of Pennsylvania, published a study this week in the Journal of Clinical Investigation, with colleague Benjamin Glaser, MD, from the Hadassah-Hebrew University Medical Center, Jerusalem, and colleagues. In this study, they were able to replicate human pancreatic beta cells - the cells in our body that produce the critical hormone insulin - in a mouse model in which donor cells were transplanted. The newly replicated cells retained features of mature beta cells and showed a physiological response to glucose.

17 Jan 2014

Research shows biological link between paternal diet and health of offspring

Research involving rats suggests that there is a biological link between paternal diet, bodyweight and health at the time of conception and the health of his offspring. In a new research report published online in The FASEB Journal, scientists show that if male rats ate a high fat diet, had diabetes and were obese, their offspring had altered gene expression in two important metabolic tissues--pancreas and fat (even though they were not yet obese).

16 Jan 2014

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

A Montr-al research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in today's printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk.

15 Jan 2014

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

AstraZeneca and Bristol-Myers Squibb Company announced the U.S. Food and Drug Administration approved Farxiga™ [far-SEE-ga] (dapagliflozin), a once-daily oral treatment indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

13 Jan 2014

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.

13 Jan 2014

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Researchers at Joslin Diabetes Center have discovered that a hormone long associated with weight loss and improved glucose metabolism is linked to activation of calorie-burning brown fat.

10 Jan 2014

Brown University biochemist targets diabetes

People with type 2 diabetes can make insulin but their bodies use it so poorly that glucose levels run amok. It's been difficult for scientists to understand what's going awry in the way that tiny, fast-moving proteins signal and regulate glucose metabolism. As a result, while drugs can help somewhat, many patients still must monitor their glucose and inject insulin.

10 Jan 2014

Low doses of anticancer drug can prevent development of diabetes mellitus type 1

Very low doses of a drug used to treat certain types of cancer protect the insulin-producing cells in the pancreas and prevent the development of diabetes mellitus type 1 in mice. The medicine works by lowering the level of so-called sterile inflammation. The findings have been made by researchers from the University of Copenhagen, the Technical University of Denmark and the University of Southern Denmark working with researchers in Belgium, Italy, Canada, Netherlands and the USA.

9 Jan 2014

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Gastric bypass surgery is a type of bariatric operation that results in weight loss and stimulates metabolic effects that treat diabetes and other cardiovascular risk factors such as diabetes, high cholesterol, and hypertension.

9 Jan 2014

Study explores relationship between avocado consumption, satiety and blood sugar

New research published in the November issue of Nutrition Journal reports adding one-half of a fresh avocado to a lunch may have helped healthy, overweight people feel more satisfied and reduced their desire to eat following a meal. The study was funded by the Hass Avocado Board.

9 Jan 2014

StemGenex offers stem cell treatment studies to patients diagnosed with diabetes, neurological diseases

According to The American Diabetes Association there are over 25 million people in the US living with diabetes. These patients are suffering from complications such as heart disease, stroke, high blood pressure, blindness, kidney disease, neuropathy and amputation.

8 Jan 2014

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

In 2004, a form of cancer known as neuroblastoma claimed the life of Alexandra (Alex) Scott, a little girl who gained national attention for using her lemonade stand to raise money for cancer research.

8 Jan 2014

JDRF joins with Brehm Center to investigate about lost beta cell function in type 1 diabetes

JDRF announced today the funding of an approximately $1 million collaboration with the University of Michigan's Brehm Center and the Brehm Coalition to evaluate a new hypothesis on why beta cells lose their ability to produce insulin, resulting in a diagnosis of type 1 diabetes (T1D).

8 Jan 2014

Research reveals two new genetic causes of neonatal diabetes

Research by the University of Exeter Medical School has revealed two new genetic causes of neonatal diabetes.

8 Jan 2014

Insulin News and Research

Further Reading

Trials, and a few unexpected triumphs, for insurance exchanges

Novo Nordisk launches insulin delivery device NovoPen Echo in the U.S.

Home blood pressure best guide to metabolic risk

Eating high levels of flavonoids found in berries, tea, and chocolate offer protection from type 2 diabetes

U of T researchers find no evidence to support 'blood-type' diet theory

Researchers managed to replicate human pancreatic beta cells in mouse model

Research shows biological link between paternal diet and health of offspring

New study examines factors that may lead to end stage renal disease

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Brown University biochemist targets diabetes

Low doses of anticancer drug can prevent development of diabetes mellitus type 1

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Study explores relationship between avocado consumption, satiety and blood sugar

StemGenex offers stem cell treatment studies to patients diagnosed with diabetes, neurological diseases

Professor receives ALSF grant to develop cancer vaccine technology that help children to have healthy life

JDRF joins with Brehm Center to investigate about lost beta cell function in type 1 diabetes

Research reveals two new genetic causes of neonatal diabetes

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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