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New RNA therapies for the treatment of heart failure and organ fibrosis

RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based compounds is far from being fully tapped, as RNA allows for entirely new therapeutic approaches.

1 Feb 2022

Study reveals seven major determinants of mortality risk for patients with COVD-19 and thoracic cancer

The risk of death for patients with SARS-CoV-2 infection and thoracic cancer is based on seven major determinants, according to research published in the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer.

1 Feb 2022

New machine-learning model could speed up the process of developing new medicines

Antibodies, small proteins produced by the immune system, can attach to specific parts of a virus to neutralize it.

1 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

Scientists discover new insights about lymphangioleiomyomatosis

Researchers have discovered new insights about lymphangioleiomyomatosis (LAM), a rare lung disease, which affects about 1 in 200,00 Americans and commonly features the growth of abnormal cells in different tissues and organs, including the lungs.

1 Feb 2022

Impact of using AI to generate primers for detection of SARS-CoV-2 Omicron variant

In a new study, researchers designed artificial intelligence (AI)-based primers for the SARS-CoV-2 Omicron variant.

1 Feb 2022

Researchers explore natural SARS-CoV-2 infection in pet rabbits in France

In a new study, researchers reported the first evidence of natural SARS-CoV-2 infections among domestic rabbits in France.

1 Feb 2022

Win an EVOLVE Manual Pipette Starter Pack from INTEGRA

INTEGRA Biosciences is giving labs a chance to win one of 10 EVOLVE Manual Pipette Starter Packs.

From INTEGRA Biosciences 1 Feb 2022

Researchers develop new technique to open the blood-brain barrier in lab animals

University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier.

31 Jan 2022

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Fusion oncogenes, such as RET- and NTRK-gene fusions, are associated with more invasive pediatric thyroid cancers, correlating with the highest risk of metastases and a lower likelihood of achieving remission one year after initial therapy, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

31 Jan 2022

Growth factor can powerfully counter the harmful effects of inflammatory bowel disease

A growth factor protein produced by rare immune cells in the intestine can protect against the effects of inflammatory bowel disease (IBD), according to a new discovery from Weill Cornell Medicine researchers.

31 Jan 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

It’s Day 6 of covid, and a rapid antigen test comes back positive. stay home, say virologists.

What does it mean if a person's rapid antigen test result comes back positive after five days of isolation due to covid-19? According to the experts, that person is most likely still carrying a viral load high enough to infect others.

31 Jan 2022

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

A new study by Norwegian researchers suggests that vaccine-induced immunological memory and the activation of recall responses in the body yields similar coverage for Omicron and Delta variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available on the medRxiv* preprint server while it undergoes peer review.

31 Jan 2022

Scientists assemble carbon nanotubes in a new way to deliver cancer drugs

Fundamental science often finds applications beyond its original focus. Previously, scientists found applications for small diameter carbon nanotube porins in energy technology.

29 Jan 2022

New app and lab kit transform a smartphone into COVID-19 / flu detection system

In a potential game changer for COVID-19 pandemic control efforts, a new cell phone app and lab kit have transformed a smartphone into a COVID-19 / flu detection system.

29 Jan 2022

Research uncovers how lactic acid disrupts the body's defense against tumors

In cancer research, it has long been known that lactic acid, or lactate, is produced in large quantities by cancer cells and that this lactic acid disrupts our defense against tumors.

29 Jan 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

Researchers receive £4.9 million to investigate pioneering biological electronics

Researchers from universities across the UK, led by the University of Bristol, have been awarded £4.9 million from the Biotechnology and Biological Sciences Research Council (BBSRC), the UK's largest bioscience funder, to investigate how electrons and energy flow through biological molecules by building artificial protein-based wires and circuits.

29 Jan 2022

Laboratory News and Research

New RNA therapies for the treatment of heart failure and organ fibrosis

Study reveals seven major determinants of mortality risk for patients with COVD-19 and thoracic cancer

New machine-learning model could speed up the process of developing new medicines

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Scientists discover new insights about lymphangioleiomyomatosis

Impact of using AI to generate primers for detection of SARS-CoV-2 Omicron variant

Researchers explore natural SARS-CoV-2 infection in pet rabbits in France

Win an EVOLVE Manual Pipette Starter Pack from INTEGRA

Researchers develop new technique to open the blood-brain barrier in lab animals

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Growth factor can powerfully counter the harmful effects of inflammatory bowel disease

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Study reveals potential mechanism for iron accumulation in the aging brain

It’s Day 6 of covid, and a rapid antigen test comes back positive. stay home, say virologists.

Vaccine-induced immunological memory is similar for Omicron and Delta SARS-CoV-2 variants

Scientists assemble carbon nanotubes in a new way to deliver cancer drugs

New app and lab kit transform a smartphone into COVID-19 / flu detection system

Research uncovers how lactic acid disrupts the body's defense against tumors

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Researchers receive £4.9 million to investigate pioneering biological electronics

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