Immune System News and Research

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"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

There are many lingering mysteries from the COVID-19 pandemic. For instance, why does SARS-CoV-2, the virus behind the disease, cause severe symptoms in some patients, while many other coronaviruses don't? And what causes strange symptoms to persist even after the infection has been cleared from a person's system?

30 Jan 2024

Impact of nirsevimab immunization on pediatric RSV-related hospitalizations in Luxembourg

Respiratory syncytial virus (RSV) is one of the main reasons leading to hospitalization among young children worldwide and each year, an estimated 101,000 children below the age of 5 years die due to RSV infections.

30 Jan 2024

New technology increases visibility of cancer cells to the immune system

A new technology to increase visibility of cancer cells to the immune system using CRISPR has been developed, and could lead to a new way to treat cancer.

30 Jan 2024

New research identifies immune system activity as likely cause of long Covid

New research has revealed changes in our blood proteins caused by our body’s own immune defenses are the likely cause of long Covid.

30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Cancer Research UK-funded scientists have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs.

29 Jan 2024

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

NewsMedical speaks with Chao Ma, Ph.D. a Research Assistant Professor at New York University Tandon School of Engineering, ahead of his presentation at SLAS 2024.

From Society for Laboratory Automation and Screening (SLAS) 29 Jan 2024

Interventions for mood show promise for the management of IBD in improving mental health, inflammation and disease outcomes

Researchers performed a meta-analysis to explore the impact of mood interventions on inflammatory disease activity in inflammatory bowel disease (IBD).

29 Jan 2024

How does the nasal cavity's immune system combat SARS-CoV-2?

Researchers discovered that CD4+ and CD8+ T cells play a crucial role in clearing COVID-19 infection in the nasal cavity but have limited impact on lung infections, with implications for understanding and treating the virus.

28 Jan 2024

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

Immune system protein can be manipulated to help fight bowel cancer

A protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU).

27 Jan 2024

Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2

Scientists at La Jolla Institute for Immunology (LJI) have found direct evidence that exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2. In fact, prior exposure to a common cold coronavirus appears to partially protect mice from lung damage during a subsequent SARS-CoV-2 infection.

27 Jan 2024

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

27 Jan 2024

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system's ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January.

27 Jan 2024

Low-dose radiation shows promise as treatment for brain injury and stroke

Traumatic brain injury (TBI) and ischemic stroke are major public health concerns and leading causes of death and disability worldwide.

27 Jan 2024

Study offers insights into who's at risk for long COVID among immunocompromised patients

Early in the pandemic, clinicians noticed that certain immunocompromised patients were experiencing persistent SARS-CoV-2 infections, some lasting weeks to months at a time.

26 Jan 2024

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Over 700 million people were infected and almost seven million died, making SARS-CoV-2 the most devastating pandemic of the 21st century.

25 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million from The Leona M. and Harry B. Helmsley Charitable Trust to support an innovative research project aimed at understanding the early stages of Crohn's disease before noticeable symptoms develop.

25 Jan 2024

New insights into why immunotherapy works for some cancers, not others

A multi-institutional study co-authored by University of Texas at Arlington scientists uncovered a mechanism by which cancer cells prevent the immune system from activating and attacking the cancerous invaders.

24 Jan 2024

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Immune System News and Research

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

Impact of nirsevimab immunization on pediatric RSV-related hospitalizations in Luxembourg

New technology increases visibility of cancer cells to the immune system

New research identifies immune system activity as likely cause of long Covid

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

Interventions for mood show promise for the management of IBD in improving mental health, inflammation and disease outcomes

How does the nasal cavity's immune system combat SARS-CoV-2?

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

Immune system protein can be manipulated to help fight bowel cancer

Prior exposure to common cold coronaviruses can train T cells to fight SARS-CoV-2

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Low-dose radiation shows promise as treatment for brain injury and stroke

Study offers insights into who's at risk for long COVID among immunocompromised patients

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

New insights into why immunotherapy works for some cancers, not others

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