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Study: Brain hormones could improve metabolism and fight obesity

A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice.

3 Feb 2021

New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma.

2 Feb 2021

Study shows link between periodontitis and COVID-19 complications

COVID-19 patients are at least three times more likely to experience complications if they also have gum disease, according to research published today in the Journal of Clinical Periodontology, the official publication of the European Federation of Periodontology.

2 Feb 2021

Iron release can be detrimental to the heart, study suggests

A process that releases iron in response to stress may contribute to heart failure, and blocking this process could be a way of protecting the heart, suggests a study in mice published today in eLife.

2 Feb 2021

Study shows safety and effectiveness of two recommended ICU sedatives

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia.

2 Feb 2021

Antiviral compound GC-376 shows efficacy against SARS-CoV-2 in vivo

Over the past months, many potential antivirals against SARS-CoV-2 have been identified as deserving further development to target several viral proteins. A new study deals with one such molecule, the viral main protease (Mpro) inhibitor GC-376, and describes its efficacy in inhibiting virus-host interaction.

2 Feb 2021

CU Boulder research offers clues to why psychiatric drugs help only some people

New CU Boulder research, published in the journal eLIfe, sheds light on one reason those individual differences may exist. Turns out a key protein in the brain called AKT may function differently in males than females.

1 Feb 2021

NYU Dentistry researcher receives NIH grant to study mitochondrial permeability transition

The National Institute of General Medical Sciences, part of the National Institutes of Health, has awarded NYU College of Dentistry's Evgeny Pavlov a grant to study a phenomenon called mitochondrial permeability transition, one of the central causes of tissue damage during stroke and heart attack.

1 Feb 2021

Nurses play crucial role in helping reduce stress for families of ICU patients

Nurses play a crucial role in helping to reduce the stress experienced by family members of critically ill patients, according to an article in Critical Care Nurse (CCN).

1 Feb 2021

Women are less likely to undergo CABG, may experience worse outcomes after surgery

Women are significantly less likely than men to undergo coronary artery bypass grafting (CABG) using guideline-recommended approaches, which may result in worse outcomes after surgery, according to a scientific presentation at the 57th Annual Meeting of The Society of Thoracic Surgeons.

31 Jan 2021

Researchers explore how the current practice of nephrology may have racist ideologies

There is a growing awareness of systematic inequality and structural racism in American society. Science and medicine are no exception, as evidenced by historical instances of discrimination and overt racism.

30 Jan 2021

Researchers examine the connection between lung cancer and COVID-19

On February 27, 2020, the flagship journal of the International Association for the Study of Lung Cancer, the Journal of Thoracic Oncology, published a case study that described two patients from Wuhan, China who recently underwent lung lobectomies for adenocarcinoma and were retrospectively found to have had COVID-19 at the time of surgery.

30 Jan 2021

Study shows critical role of trauma and emergency surgeons in patient satisfaction

Trauma patients and patients who need emergency surgery have little to no opportunity to get acquainted with the surgeon and team that will perform their operation.

29 Jan 2021

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

New research from the University of Sheffield has found being overweight is an additional burden on brain health and it may exacerbate Alzheimer's disease.

29 Jan 2021

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

29 Jan 2021

Black, Hispanic children less likely to get imaging tests compared to White kids

A study led by UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine shows that Black children are 18% less likely to get imaging tests as part of their emergency department visit compared to White children.

29 Jan 2021

Researchers identify new strategy to protect offspring from prenatal stress

New research from the University of Iowa and University Hospitals Cleveland Medical Center demonstrates that offspring can be protected from the effects of prenatal stress by administering a neuroprotective compound during pregnancy.

29 Jan 2021

Study uncovers genetic similarities between PTSD and other mental health disorders

Attempts to identify the genetic causes of neuropsychiatric diseases such as post-traumatic stress disorder (PTSD) through large-scale genome-wide analyses have yielded thousands of potential links.

28 Jan 2021

Insomnia patients commonly underestimate their actual sleep behavior

People with sleep disorders commonly have a misperception about their actual sleep behavior. A research group led by Karin Trimmel and Stefan Seidel from MedUni Vienna's Department of Neurology (Outpatient Clinic for Sleep Disorders and Sleep-Related Disorders) analyzed polysomnography results to identify the types of sleep disorder that are associated with a discrepancy between self-reported and objective sleep parameters and whether there are any factors that influence this.

28 Jan 2021

Stress News and Research

Study: Brain hormones could improve metabolism and fight obesity

New process separates beneficial glucocorticoids from unwanted side-effects

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Study shows link between periodontitis and COVID-19 complications

Iron release can be detrimental to the heart, study suggests

Study shows safety and effectiveness of two recommended ICU sedatives

Antiviral compound GC-376 shows efficacy against SARS-CoV-2 in vivo

CU Boulder research offers clues to why psychiatric drugs help only some people

NYU Dentistry researcher receives NIH grant to study mitochondrial permeability transition

Nurses play crucial role in helping reduce stress for families of ICU patients

Women are less likely to undergo CABG, may experience worse outcomes after surgery

Researchers explore how the current practice of nephrology may have racist ideologies

Researchers examine the connection between lung cancer and COVID-19

Study shows critical role of trauma and emergency surgeons in patient satisfaction

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Black, Hispanic children less likely to get imaging tests compared to White kids

Researchers identify new strategy to protect offspring from prenatal stress

Study uncovers genetic similarities between PTSD and other mental health disorders

Insomnia patients commonly underestimate their actual sleep behavior

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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