Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Children with Type 2 diabetes are at high risk to develop heart, kidney and eye problems

The news about youth and diabetes keeps getting worse. The latest data from the national TODAY diabetes study shows that children who develop Type 2 diabetes are at high risk to develop heart, kidney and eye problems faster and at a higher rate than people who acquire Type 2 diabetes as adults.

26 May 2013

New evidence shows intensive insulin therapy does not provide substantial benefits

High blood glucose is associated with poor outcomes in hospitalized patients, and use of intensive insulin therapy (IIT) to control hyperglycemia is a common practice in hospitals. But the recent evidence does not show a consistent benefit and even shows harms associated with the use of IIT, according to the American College of Physicians' (ACP) Clinical Guidelines Committee in a new evidence-based paper published today online in the American Journal of Medical Quality.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

Obesity directly tied to several cancers

"Obesity is a major risk factor for developing cancer, roughly the equivalent of tobacco use, and both are potentially reversible. Further, obese cancer patients do worse in surgery, with radiation or on chemotherapy - worse by any measure." Karen Basen-Engquist, Ph.D., Director of MD Anderson's new Center for Energy Balance in Cancer Prevention and Survivorship and professor of Behavioral Science.

22 May 2013

Study provides comprehensive blueprint for understanding diabetes

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.

22 May 2013

Newly discovered immune protein has potential to stop or reverse type 1 diabetes

Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been destroyed.

21 May 2013

Research: Frequency of candy consumption is not associated with adverse health risks

At a time when the spotlight is focused on obesity more than ever, new research suggests that frequency of candy consumption is not associated with weight or certain adverse health risks.

21 May 2013

UIC researchers to study gender differences in how the heart uses and stores fat

Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat -- its main energy source -- and how changes in fat metabolism play a role in heart disease, under a new $2 million, 4-year grant from the National Heart, Lung and Blood Institute.

21 May 2013

Study shows treatment of sleep apnea in patients with prediabetes improves blood sugar levels

Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in Philadelphia.

20 May 2013

Targeting glucagon action: A new frontier for regulating diabetes

For the first time, scientists at the Toronto General Research Institute showed that targeting glucagon action in the brain may be a new frontier for regulating diabetes.

20 May 2013

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

An exploration of electronic "screen time" and sleep on mood, memory and learning was given the top Addiction Science Award at the 2013 Intel International Science and Engineering Fair - the world's largest science competition for high school students.

20 May 2013

Newer class of diabetes medications may also improve cardiovascular health, researchers report

A newer class of medications used to control blood sugar levels in type 2 diabetics may also improve cardiovascular health, researchers from The Ohio State University Wexner Medical Center reported in a new meta-analysis presented yesterday at the American Society of Hypertension's Annual Scientific Meeting and Exposition.

17 May 2013

FDA clears Oramed Pharmaceuticals' IND for ORMD-0801

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that the United States Food and Drug Administration has cleared the Company's Investigational New Drug application for ORMD-0801, its oral insulin capsule.

17 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

Injectable nanogel can monitor blood-sugar levels, secrete insulin when needed

Injectable nanoparticles developed at MIT may someday eliminate the need for patients with Type 1 diabetes to constantly monitor their blood-sugar levels and inject themselves with insulin.

17 May 2013

Statistics reveal that about 79 million adult Americans walk around with prediabetes

Diabetes is one of the most misunderstood medical conditions. "It's not just about sugar. It's about your heart," says Nancy Ryan, RD, BC-ADM, a registered dietitian, board-certified in advanced diabetes management at Greenwich Hospital in Greenwich, Connecticut.

16 May 2013

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

A dominant and useful bacterium called Akkermansia muciniphila is present in the intestinal system of all humans, from babies to the elderly. This microorganism is found in the intestinal mucus layer that protects against intruders.

16 May 2013

Regular marijuana use is associated with favorable indices related to diabetic control, say investigators

Regular marijuana use is associated with favorable indices related to diabetic control, say investigators. They found that current marijuana users had significantly lower fasting insulin and were less likely to be insulin resistant, even after excluding patients with a diagnosis of diabetes mellitus. Their findings are reported in the current issue of The American Journal of Medicine.

15 May 2013

Noninvasive imaging tests may play bigger role in diabetes management

New approaches to applying noninvasive imaging tests such as computed tomography, magnetic resonance, and positron emission tomography may play a bigger role in evaluating and managing patients with diabetes.

14 May 2013

Lexicon Pharmaceuticals advances Phase 2 clinical trial of LX4211 in patients with type 1 diabetes

Lexicon Pharmaceuticals, Inc. announced today that it is progressing into the placebo-controlled portion of its Phase 2 clinical trial of LX4211 in patients with type 1 diabetes, having successfully completed the open-label, pioneer portion of the trial.

10 May 2013

Insulin News and Research

Further Reading

Children with Type 2 diabetes are at high risk to develop heart, kidney and eye problems

New evidence shows intensive insulin therapy does not provide substantial benefits

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Obesity directly tied to several cancers

Study provides comprehensive blueprint for understanding diabetes

Newly discovered immune protein has potential to stop or reverse type 1 diabetes

Research: Frequency of candy consumption is not associated with adverse health risks

UIC researchers to study gender differences in how the heart uses and stores fat

Study shows treatment of sleep apnea in patients with prediabetes improves blood sugar levels

Targeting glucagon action: A new frontier for regulating diabetes

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

Newer class of diabetes medications may also improve cardiovascular health, researchers report

FDA clears Oramed Pharmaceuticals' IND for ORMD-0801

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Injectable nanogel can monitor blood-sugar levels, secrete insulin when needed

Statistics reveal that about 79 million adult Americans walk around with prediabetes

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

Regular marijuana use is associated with favorable indices related to diabetic control, say investigators

Noninvasive imaging tests may play bigger role in diabetes management

Lexicon Pharmaceuticals advances Phase 2 clinical trial of LX4211 in patients with type 1 diabetes

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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