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Researchers uncover how vitamins A and C act to modify epigenetic cell memory

Vitamins A and C aren't just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic 'memory' held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one identity to another.

12 Oct 2016

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

After analyzing 10 years of medical tests on more than 2,700 people in a federally funded heart disease study, researchers at Johns Hopkins Medicine and elsewhere conclude that taking calcium in the form of supplements may raise the risk of plaque buildup in arteries and heart damage, although a diet high in calcium-rich foods appears be protective.

12 Oct 2016

Financial difficulties may impact treatment outcomes for cancer patients

Financial difficulties can significantly impact a cancer patient's quality of life during treatment and may even increase their risk of death, according to the results of a pooled analysis presented at the ESMO 2016 Congress in Copenhagen.

12 Oct 2016

An inclusive approach to COPD research: an interview with Dr David Leather

About eight years ago the WHO put out a call saying that we needed data that better represented real world patients. Our ambition was to create evidence earlier in the life cycle of medicine that better represented the population that would...

11 Oct 2016

Study highlights burden, poor prognosis of head and neck cancers linked to tobacco/alcohol

A nationwide study of head and neck cancers in France has revealed that the true burden of the disease is underestimated by at least one-third, and that head and neck cancers carry a very high risk of secondary primary cancers, according to two presentations at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Fulvestrant significantly increases progression-free survival in women with hormone-receptor-positive advanced breast cancer, particularly those with less aggressive lower-volume disease, researchers reported at the ESMO 2016 Congress in Copenhagen

8 Oct 2016

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

The first-in-human dose escalation study of the pan-FGFR (fibroblast growth factor receptor) inhibitor BAY 1163877 in patients with treatment-refractory locally advanced or metastatic solid tumours were reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Penn State scientists develop citrate-based fluorescent sensor for diagnosis of cystic fibrosis

Penn State biomaterials scientists have developed a new, inexpensive method for detecting salt concentrations in sweat or other bodily fluids.

7 Oct 2016

Diamond publishes milestone paper that reveals discovery of genetic triggers behind birth defects

Researchers at the UK's national synchrotron facility, Diamond Light Source, have just published the 5000th scientific paper using data from the facility. This milestone marks a significant step for the synchrotron that is used by over 8,000 scientists each year.

7 Oct 2016

Added benefit not proven for melanoma drug, IQWiG finds

Talimogene laherparepvec has been approved since December 2015 for adults with advanced melanoma.

7 Oct 2016

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

Selexipag is approved for long-term treatment of pulmonary arterial hypertension (PAH) in adults with moderate to severe symptoms.

7 Oct 2016

Researchers to explore potential roles of tumor-suppressor gene in kidney cancer

Renal cell carcinoma is the most common type of kidney cancer, and African-Americans and males appear most at risk for this disease that can be asymptomatic until it has spread and become highly lethal, said Dr. Vinata B. Lokeshwar, cancer researcher and chair of the Department of Biochemistry and Molecular Biology at the Medical College of Georgia at Augusta University.

7 Oct 2016

Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery

Neoadjuvant immunotherapy with the PD-1 inhibitor nivolumab is safe and feasible prior to surgery for early lung cancer, researchers reported at the ESMO 2016 Congress in Copenhagen.

7 Oct 2016

Studies look at alternative ways to overcome barriers and improve cancer screening rates

Early diagnosis of cancer is linked to better survival rates. Unfortunately, participation rates for cancer screening worldwide are low even when screening programmes are free.

6 Oct 2016

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication.

6 Oct 2016

Hard-to-control asthma in children has significant baseline features, study finds

Bronchodilator responsiveness, nasal inflammation and allergy were among the most significant baseline features that distinguished hard-to-control asthma in inner-city children and adolescents.

6 Oct 2016

Frailty screening could help improve outcomes in older surgery patients

Identifying frailty in older patients could increase their chances of surviving surgery, as well as improve their overall outcomes, according to a new study posted online today in The Annals of Thoracic Surgery.

6 Oct 2016

Researchers discover Achilles heel of common bacteria that causes fatal infections

Pseudomonas aeruginosa is a common bacterium of our environment. It can however become a formidable pathogen causing fatal infections, especially in intubated patients, people suffering from cystic fibrosis or severe burns.

6 Oct 2016

Exposure to e-cigarette vapour induces negligible or no oxidative damage to lung epithelial cells

E-cigarette vapour is much less harmful to lung cells than cigarette smoke. Lab tests show that, unlike tobacco smoke, which causes oxidative stress and cell death, e-cigarette vapour does not. Oxidative stress and cell death are driving factors in the development of many smoking-related diseases such as COPD and lung cancer.

5 Oct 2016

Coral study provides insight into evolutionary development of mesoderm

Corals first appeared on earth nearly half a billion years ago during the Cambrian Period of the Paleozoic Era. The ancient Greek philosopher Aristotle categorized corals as zoophyta, or "plant-animals", due to their plant-like appearance.

5 Oct 2016

Lungs News and Research

Researchers uncover how vitamins A and C act to modify epigenetic cell memory

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

Financial difficulties may impact treatment outcomes for cancer patients

An inclusive approach to COPD research: an interview with Dr David Leather

Study highlights burden, poor prognosis of head and neck cancers linked to tobacco/alcohol

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

Penn State scientists develop citrate-based fluorescent sensor for diagnosis of cystic fibrosis

Diamond publishes milestone paper that reveals discovery of genetic triggers behind birth defects

Added benefit not proven for melanoma drug, IQWiG finds

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

Researchers to explore potential roles of tumor-suppressor gene in kidney cancer

Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery

Studies look at alternative ways to overcome barriers and improve cancer screening rates

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

Hard-to-control asthma in children has significant baseline features, study finds

Frailty screening could help improve outcomes in older surgery patients

Researchers discover Achilles heel of common bacteria that causes fatal infections

Exposure to e-cigarette vapour induces negligible or no oxidative damage to lung epithelial cells

Coral study provides insight into evolutionary development of mesoderm

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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