Immune System News and Research

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New screening platform can be used to discover more effective drugs for type 1 diabetes

With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving.

16 Dec 2020

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Maresin and resolvin, produced by the body from omega-3 fatty acids, can help repair tissue damaged by periodontal disease.

16 Dec 2020

Scientists discover how a 'sociable' protein can hold clues about Alzheimer's origin

An international team of scientists led by the ESRF, the European Synchrotron, have found how the ECSIT protein dictates the behavior of proteins linked to the energy activity in mitochondria, which is largely affected in Alzheimer's disease.

16 Dec 2020

LRA survey: Two-thirds of people with lupus are willing to take COVID-19 vaccine

Two out of three people with lupus (64%) are willing to take a COVID-19 vaccine if it is free and determined safe by scientists according to results of a survey conducted by the Lupus Research Alliance.

16 Dec 2020

Researchers identify new immune cell that acts as major driver of breast cancer growth

Breast cancer is the most common cancer in women worldwide, but many immunotherapies have had limited success in treating aggressive forms of the disease.

16 Dec 2020

AI-based study of social media maps SARS-CoV-2 vaccine hesitancy across the US

Researchers from the University of Rochester, USA, has produced an AI-based study that analyzes the social media platform Twitter to gauge public opinions in the US surrounding SARS-CoV-2 vaccines to shed greater light on this issue.

15 Dec 2020

Tumor's stiff-arm tactic limits the effectiveness of immunotherapeutics

In a paper just published in the Journal for the Immunotherapy of Cancer (doi:10.1136/jitc-2020-001712), Dr Herbert, Head of Discovery at InsideOutBio, asks whether cancer cells stiff-arm immune cells just like rugby players push off defenders from the other team.

15 Dec 2020

Electrical impulses may help reduce the complications of arterial hypertension

Electrical impulses applied to a particular branch of the vagus nerve could be used in the future to reduce complications of arterial hypertension.

15 Dec 2020

Pulmonary hypertension drug may become a treatment option for cancer

A drug used to treat pulmonary hypertension significantly reduced the capacity of tumor cells to migrate and invade other tissues in trials involving pancreatic, ovarian, breast cancer, and leukemia cell lines.

15 Dec 2020

First enzyme-driven biocatalytic production of nucleic acid building blocks

Researchers from TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of nucleic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics.

15 Dec 2020

SIMON – The Machine Learning Platform Paving the Future of Vaccine Development

A machine learning algorithm developed by the Oxford Vaccine Group promises more effective vaccine development for several diseases, including COVID-19.

15 Dec 2020

Reliable Antibodies Testing for SARS-CoV-2

In this interview, Poncho Meisenheimer, VP of R&D at Promega, talks to News-Medical Life Sciences about the importance of having the reliability for SARS-Co-V-2 antibody tests.

From Promega Corporation 15 Dec 2020

Study: Flavoring chemicals of e-cigarette vapor alone can measurably damage the lungs

Known for their appetizing flavors, such as bubblegum, banana and strawberry, e-cigarettes continue to grow in popularity around the world. Promoted by makers as a "healthy" alternative to regular tobacco cigarettes, researchers are finding e-cigarettes, or vaping, still result in injury to the lungs.

15 Dec 2020

FDA approves first IGA in GalSafe pigs for human food, promising therapeutic uses

Today, the U.S. Food and Drug Administration approved a first-of-its-kind intentional genomic alteration (IGA) in a line of domestic pigs, referred to as GalSafe pigs, which may be used for food or human therapeutics.

15 Dec 2020

COVID-19 vaccine shows the long-term value of curiosity-driven basic research

The most promising vaccine against the coronavirus to date is also an example of the long-term value of curiosity-driven basic research and its funding by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation).

15 Dec 2020

Microglial surveillance helps prevent seizure activity in the brain

An important part of the brain's immune system, cells called microglia constantly extend and retract "branches" from their cell body to survey their environment.

14 Dec 2020

ACAAI releases guidance related to risk of allergic reactions to Pfizer-BioNTech COVID-19 vaccine

With the emergency use authorization of the Pfizer-BioNTech COVID-19 vaccine by the FDA on December 11, 2020, and distribution beginning today, the American College of Allergy, Asthma and Immunology COVID-19 Vaccine Task Force recommends the following guidance related to risk of an allergic reaction on vaccination for those who receive the vaccine.

14 Dec 2020

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute, an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.

14 Dec 2020

New method shortens the timeline to generate mice for vaccine research

To develop vaccines and investigate human immune responses, scientists rely on a variety of animal models, including mice that can produce human antibodies through genetically engineered B cell receptors, which are specialized antibodies bound to the B cell membrane.

14 Dec 2020

Multisystem immune-related adverse events linked with improved survival from immunotherapy in NSCLC

The results of a large, retrospective study of patients who received a form of immunotherapy for non-small cell lung cancer (NSCLC) revealed that patients may get more than one immune-related side effect, and identified a correlation between these multisystem immune-related adverse events (irAEs) and improved patient survival.

14 Dec 2020

Immune System News and Research

New screening platform can be used to discover more effective drugs for type 1 diabetes

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Scientists discover how a 'sociable' protein can hold clues about Alzheimer's origin

LRA survey: Two-thirds of people with lupus are willing to take COVID-19 vaccine

Researchers identify new immune cell that acts as major driver of breast cancer growth

AI-based study of social media maps SARS-CoV-2 vaccine hesitancy across the US

Tumor's stiff-arm tactic limits the effectiveness of immunotherapeutics

Electrical impulses may help reduce the complications of arterial hypertension

Pulmonary hypertension drug may become a treatment option for cancer

First enzyme-driven biocatalytic production of nucleic acid building blocks

SIMON – The Machine Learning Platform Paving the Future of Vaccine Development

Reliable Antibodies Testing for SARS-CoV-2

Study: Flavoring chemicals of e-cigarette vapor alone can measurably damage the lungs

FDA approves first IGA in GalSafe pigs for human food, promising therapeutic uses

COVID-19 vaccine shows the long-term value of curiosity-driven basic research

Microglial surveillance helps prevent seizure activity in the brain

ACAAI releases guidance related to risk of allergic reactions to Pfizer-BioNTech COVID-19 vaccine

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

New method shortens the timeline to generate mice for vaccine research

Multisystem immune-related adverse events linked with improved survival from immunotherapy in NSCLC

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