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Researchers identify cellular pathway to potentially block disease-inducing inflammation

Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases.

10 Oct 2011

Potential new drug could treat mixed-lineage leukaemia

A team lead by Cancer Research UK scientists have shown that a potential new drug could treat mixed-lineage leukaemia (MLL), the most common form of leukaemia in babies, according to a study published in Nature today.

3 Oct 2011

HeartWare announces updated clinical data from BTT study, ADVANCE and CAP

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced updated clinical data from its bridge to heart transplantation (BTT) study, ADVANCE, and the Continued Access Protocol.

3 Oct 2011

Combination therapy improves outcomes for liver cancer patients: Study

A combination of an oral drug, called sorafenib, and a method for injecting microbeads of chemotherapy directly into tumors has been proven safe for liver cancer patients and may improve outcomes for those who have these fast-growing, deadly tumors whose numbers are on the rise in the U.S.

1 Oct 2011

Bristol-Myers to present abstracts on research in liver disease at The Liver Meeting 2011

Bristol-Myers Squibb Company announced today that 22 abstracts on the Company's research in liver disease have been accepted for presentation at The Liver Meeting 2011, the 62nd annual meeting of the American Association for the Study of Liver Diseases, in San Francisco, November 4 - 8.

1 Oct 2011

Dialysis patients with kidney failure more likely to develop serious complications from flu

For most people, the flu is a temporary setback that makes them feel under the weather for a week or two. For dialysis patients with kidney failure, however, the flu is a serious health threat that can lead to pneumonia and other life-threatening complications.

1 Oct 2011

UCLA researchers develop risk scoring system to gauge risk of re-transplantation failure

Liver re-transplantation generally has an inferior outcome compared with a patient's first transplant, due to the technical demands of the surgery and because patients are often sicker than they were at the time of their first procedure.

30 Sep 2011

First patient in Turkey with Total Artificial Heart attends TUYOD meeting

In May 2011, Omer Bayrak made headlines when he became the first patient in Turkey to be discharged from the hospital using the Freedom® portable driver to power his SynCardia temporary Total Artificial Heart. Since returning home to wait for a matching donor heart, Mr. Bayrak has been enjoying his new-found celebrity as "the only man in Turkey who lives without a heart."

30 Sep 2011

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.

29 Sep 2011

AASLD publishes updated practice guidelines on hepatitis C

On Monday, September 26, 2011, the American Association for the Study of Liver Diseases published online at its journal Hepatology's website an update to its practice guidelines for hepatitis C – "An Update on Treatment of Genotype 1 Chronic Hepatitis C Virus Infection: 2011 Practice Guideline by the American Association for the Study of Liver Diseases."

29 Sep 2011

High volume liver transplant centers achieve better risk-adjusted survival rates

The shortage of available organs for transplantation has driven up use of high-risk donor livers. New research published in the October issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases, reported that high volume transplant centers more frequently utilized livers with a high donor risk index, but achieved better risk-adjusted graft and recipient survival rates compared with lower volume centers.

29 Sep 2011

Liver transplantation candidates without HCC derive greater survival benefit from LDLT

New research shows liver transplantation candidates without hepatocellular carcinoma (HCC) derive a greater survival benefit from a living donor liver transplant (LDLT) than waiting for a deceased donor liver transplant.

28 Sep 2011

U-M receives $2.2M FDA grant for 40 ongoing pediatric device projects

Adapting adult medical devices to be used for children is a common but often problematic practice across U.S. hospitals. At the University of Michigan and U-M C.S. Mott Children's Hospital, pediatricians and researchers who care for children have been leading the charge to change this. They work to create, engineer and test medical devices and curb problems that come from using tools, implants, gadgets and procedures designed for adults.

26 Sep 2011

'Time matters' in the fight against pulmonary hypertension

The Pulmonary Hypertension Association Europe (PHA EU) has launched ‘Time Matters’ a new campaign which encourages people with Pulmonary Hypertension (PH) and their friends and family to share hopes and dreams for the future in order to raise awareness of this deadly and rapidly progressive condition. By logging on to the website http://phtimematters.org and posting an entry, everybody can help the patient association take a step towards increased awareness and understanding of this devastating condition.

26 Sep 2011

EMA CHMP adopts positive opinion for Soliris to treat atypical hemolytic uremic syndrome

Alexion Pharmaceuticals, Inc. today announced that the European Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending that the therapeutic indication for Soliris® (eculizumab) be extended to include the treatment of pediatric and adult patients with atypical hemolytic uremic syndrome (aHUS) in Europe.

23 Sep 2011

NYT: Ethics probe involves kidney transplant center, Rep. Berkley

In 2008 Ms. Berkley helped lead an effort to block a move by federal regulators to close Nevada's only kidney transplant center, which her husband's medical practice helps run under a $738,000-a-year contract. She also successfully pushed regulators, as recently as March, to reverse a plan to cut Medicare reimbursement to dialysis centers, including the dozen her husband's medical practice owns.

23 Sep 2011

First Edition: September 22, 2011

In today's headlines, reports that young adults are making gains in health coverage rates.

22 Sep 2011

First ever domino liver transplant

For the first time ever, a surgical team led by Alan Hemming, MD, has successfully performed a domino transplant using a liver with a rare genetic disorder called methylmalonic acidemia.

22 Sep 2011

Molecular pathways could play important role in fight against obesity and diabetes

Researchers at the Joslin Diabetes Center have identified for the first time two molecular pathways that are critical to activating a type of "good" fat found in the body, a discovery that could play an important role in the fight against obesity and diabetes.

22 Sep 2011

Digna Biotech receives FDA Orphan Drug status for cardiotrophin-1 to treat ALF

Digna Biotech, a Spanish biotechnological company, announces that the Food and Drug Administration (FDA) granted cardiotrophin-1 (CT-1) Orphan Drug status for use in the treatment of acute liver failure.

22 Sep 2011

Transplant News and Research

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Potential new drug could treat mixed-lineage leukaemia

HeartWare announces updated clinical data from BTT study, ADVANCE and CAP

Combination therapy improves outcomes for liver cancer patients: Study

Bristol-Myers to present abstracts on research in liver disease at The Liver Meeting 2011

Dialysis patients with kidney failure more likely to develop serious complications from flu

UCLA researchers develop risk scoring system to gauge risk of re-transplantation failure

First patient in Turkey with Total Artificial Heart attends TUYOD meeting

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

AASLD publishes updated practice guidelines on hepatitis C

High volume liver transplant centers achieve better risk-adjusted survival rates

Liver transplantation candidates without HCC derive greater survival benefit from LDLT

U-M receives $2.2M FDA grant for 40 ongoing pediatric device projects

'Time matters' in the fight against pulmonary hypertension

EMA CHMP adopts positive opinion for Soliris to treat atypical hemolytic uremic syndrome

NYT: Ethics probe involves kidney transplant center, Rep. Berkley

First Edition: September 22, 2011

First ever domino liver transplant

Molecular pathways could play important role in fight against obesity and diabetes

Digna Biotech receives FDA Orphan Drug status for cardiotrophin-1 to treat ALF

Pioneering Live Cell Imaging - Yokogawa's Impact and Innovations

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

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