Precision Medicine News and Research

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Gut hormone receptor polyagonists show promise for obesity and diabetes

A new paper in the Journal of Clinical Investigation describes drugs that could help lose weight and manage type 2 diabetes mellitus (T2DM).

6 Feb 2023

What do gut microbiota have to do with Alzheimer's and dementia?

Researchers explore the preventive and therapeutic potential of gut microbiome modulation in the treatment of Alzheimer’s disease.

6 Feb 2023

Targeting a single enzyme can kill prostate cancer cells

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

Oncodesign Services looks to the future

As Oncodesign evolves into Oncodesign Services and begins its journey as an independent business, CEO Fabrice Viviani explains his hopes and plans for the company’s future.

From Oncodesign Services 3 Feb 2023

ERES IV acquires a majority stake in Oncodesign Services

Oncodesign Services, a leading Contract Research Organization (CRO) specializing in drug discovery and preclinical services in oncology and immuno-inflammation, and Elyan Partners announce the completion of the acquisition of a majority stake in Oncodesign Services by ERES IV, representing 61.58% of its share capital, from its main shareholders, including Mr. Philippe Genne, Founder of Oncodesign Services, as well as certain key shareholders and several managers and minority shareholders, following the entry into exclusive negotiations on June 30, 2022.

From Oncodesign Services 3 Feb 2023

New nanotechnology-based test can detect and profile prostate cancers even in microscopic amounts

Cedars-Sinai Cancer investigators have developed a new nanotechnology-based test that can detect and profile prostate cancers-;even in microscopic amounts.

2 Feb 2023

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

In this interview, we speak to Magdalena Kasendra at the CuSTOM Accelerator, about the organoid technology and how it has the power the revolutionize healthcare.

From Society for Laboratory Automation and Screening (SLAS) 1 Feb 2023

Effectiveness of exome and genome sequencing to detect undiagnosed syndromes

Scientists review existing literature to evaluate the advancements in genomic and exome sequencing for the accurate detection of undiagnosed syndromes.

1 Feb 2023

Study aims to better understand the effect of spinal cord stimulation on chronic pain and sleep

Often debilitating, chronic pain is one of the most common reasons individuals seek medical help. About 65 million adults in the United States are affected by chronic pain.

30 Jan 2023

International guidelines to help prevent and treat heart complications in pediatric oncology patients

The world's first international clinical guidelines to help prevent and treat heart complications in children undergoing cancer treatment have been created.

29 Jan 2023

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

A multi-institutional team led by scientists from the Medical College of Wisconsin Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who may benefit from new immunotherapies.

26 Jan 2023

Study investigates the link between lifestyle factors and risk of HPV infection

Human well-being has been linked to physical activity, diet balance, sleep quality, depression and anxiety.

25 Jan 2023

Researchers use multiplexed 3D imaging to perform molecular and morphological assessments of colorectal cancers

Researchers used multiplexed and three-dimensional imaging with machine-based learning and spatial statistics to perform molecular and morphological assessments of colorectal cancers (CRC).

24 Jan 2023

"Breathe Sweden" platform enhances collaborations in asthma, allergy, and respiratory research

"Breathe Sweden", a digital platform for researchers who collect studies on diseases and disorders of the respiratory tract, has now been launched.

24 Jan 2023

Mitochondrial dysfunction and endothelial impairment linked to many cardiovascular diseases

Many cardiovascular diseases, such as atherosclerosis, or 'hardening of the arteries,' correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels.

23 Jan 2023

Study reviews mechanistic data on new methods of allergy prevention and treatment

In a recent article published in Science Translational Medicine, researchers reviewed the cause and the underlying pathophysiology of allergic diseases.

23 Jan 2023

New resource of digital microbes created with focus on drug metabolism

Researchers at University of Galway associated with APC Microbiome Ireland, a world-leading SFI Research Centre, have created a resource of over 7,000 digital microbes – enabling computer simulations of how drug treatments work and how patients may respond.

20 Jan 2023

Precision Medicine News and Research

Gut hormone receptor polyagonists show promise for obesity and diabetes

What do gut microbiota have to do with Alzheimer's and dementia?

Targeting a single enzyme can kill prostate cancer cells

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

Oncodesign Services looks to the future

ERES IV acquires a majority stake in Oncodesign Services

New nanotechnology-based test can detect and profile prostate cancers even in microscopic amounts

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

Effectiveness of exome and genome sequencing to detect undiagnosed syndromes

Study aims to better understand the effect of spinal cord stimulation on chronic pain and sleep

International guidelines to help prevent and treat heart complications in pediatric oncology patients

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

Study investigates the link between lifestyle factors and risk of HPV infection

Researchers use multiplexed 3D imaging to perform molecular and morphological assessments of colorectal cancers

"Breathe Sweden" platform enhances collaborations in asthma, allergy, and respiratory research

Mitochondrial dysfunction and endothelial impairment linked to many cardiovascular diseases

Study reviews mechanistic data on new methods of allergy prevention and treatment

New resource of digital microbes created with focus on drug metabolism

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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