Proliferation News and Research

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Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

Gene B-myb essential in preventing tumors

A new study has confirmed that research done with zebrafish may be able to play a critical role in learning about the genetic basis of cancer and the mutations that can lead to it - and identified one gene in particular, B-myb, whose function is essential to preventing tumors.

5 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

Release of the neurotransmitter GABA halts stem cell production in the brain

Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.

1 Sep 2005

Scientists demonstrate power of new generalized screen to find function of noncoding RNAs

A team of investigators at The Scripps Research Institute and the Genomics Institute of the Novartis Research Foundation (GNF) have discovered a way to screen hundreds and potentially thousands of "noncoding" RNA molecules to discover their functions within cells.

1 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Another use for Botox - enlarged prostate

Botox, appears to alter specific cellular processes that contribute to prostate enlargement according to new study results presented by researchers from the University of Pittsburgh and Chang Gung Memorial Hospital in Taiwan at the International Continence Society annual meeting in Montreal.

31 Aug 2005

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Research led by Dr. Anne Mueller at Stanford University School of Medicine demonstrates that successful eradication of Helicobacter may not prevent future aggressive gastric lymphoma since resting B cells are left behind.

25 Aug 2005

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

In a paper published in PLoS Medicine researchers from the German Genome Research Network have analysed the expression of thousands of genes from patients with inflammatory bowel disease (ulcerative colitis and Crohn disease) using a genome wide approach to produce a comprehensive picture of which genes are activated in these conditions.

24 Aug 2005

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Discovery of a potential oncogene in ovarian cancer

Researchers at The University of Texas M. D. Anderson Cancer Center report they have discovered a potential oncogene in ovarian cancer, which is the leading cause of gynecological cancer death in U.S. women.

22 Aug 2005

Breakthrough in human stem cell research

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities.

16 Aug 2005

MiRNA is opening up a whole new way of understanding carcinogenesis

Scientists mining vast, largely unexplored regions of the human genome have identified a small handful of mini-molecules that play a major role in the development of cancer and perhaps many other diseases.

15 Aug 2005

Study results reaffirm cyclin D1 as a candidate target for molecular therapeutic control of breast tumor development

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases arise from these genetic miscues, about half of which are linked to the abnormal functioning of BRCA1.

9 Aug 2005

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases are linked to genetic miscues, about half of which are linked to BRCA1.

2 Aug 2005

Arf gene prevents excessive growth of blood vessels in the developing eye

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.

2 Aug 2005

Action of dopamine may be particularly important for understanding psychiatric conditions

Duke University Medical Center researchers have discovered a new mechanism by which chronically high levels of the neurotransmitter dopamine exert their effects on the brain.

28 Jul 2005

Broccoli may help prevent bladder cancer

Researchers have isolated compounds from the vegetable broccoli that they believe may help prevent or slow the progress of bladder cancer.

28 Jul 2005

Molecular link between a viral infection and development of a common and fatal form of liver cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have uncovered a crucial molecular link between a viral infection and development of a common and fatal form of liver cancer. In the process, they have identified a possible way to treat this disease as well as a number of other cancers.

26 Jul 2005

Crucial molecular link between a hepatitis B virus (HBV) and hepatocellular carcinoma (HCC)

21 Jul 2005

Proliferation News and Research

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Gene B-myb essential in preventing tumors

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

Release of the neurotransmitter GABA halts stem cell production in the brain

Scientists demonstrate power of new generalized screen to find function of noncoding RNAs

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Another use for Botox - enlarged prostate

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

Discovery of a potential oncogene in ovarian cancer

Breakthrough in human stem cell research

MiRNA is opening up a whole new way of understanding carcinogenesis

Study results reaffirm cyclin D1 as a candidate target for molecular therapeutic control of breast tumor development

Protein called cyclin D1 disrupts BRCA1's normal role as a cancer inhibitor

Arf gene prevents excessive growth of blood vessels in the developing eye

Action of dopamine may be particularly important for understanding psychiatric conditions

Broccoli may help prevent bladder cancer

Molecular link between a viral infection and development of a common and fatal form of liver cancer

Crucial molecular link between a hepatitis B virus (HBV) and hepatocellular carcinoma (HCC)

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