Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Sterile acellular matrices 'reliable in expander-based breast reconstruction'

Sterile human acellular dermal matrix offers reliable matrix incorporation and a low complication rate for expander-based breast reconstruction, the results of a US study indicate, which also suggest that sterilization does not affect incorporation success.

15 Oct 2012

Scientists resolve new molecular circuit controlling cellular metabolism

Cancer, diabetes, and excess body weight have one thing in common: they alter cellular metabolism. Scientists from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the Medical University of Vienna together with an international research team have jointly resolved a new molecular circuit controlling cellular metabolism.

15 Oct 2012

New insights into how miR-30d can promote healthy insulin production

Work by Michigan Technological University biologist Xiaoqing Tang is yielding new insights into how a tiny snippet of genetic material can promote healthy insulin production in mice.

13 Oct 2012

Type 2 diabetes screening: an interview with Dr Simon Griffin, MRC Epidemiology Unit at Addenbrooke’s Hospital, Cambridge

Type 2 diabetes is a condition in which the body does not make sufficient insulin or the insulin it makes doesn’t work sufficiently well to maintain a normal level of blood glucose and so the blood glucose rises.

12 Oct 2012

First picture of interaction between leptin and its receptor

Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

12 Oct 2012

Recovering Treg cells in pancreatic lymph nodes may restore insulin production in type I diabetics

The key to restoring production of insulin in type I diabetic patients, previously known as juvenile diabetes, may be in recovering the population of protective cells known T regulatory cells in the lymph nodes at the "gates" of the pancreas, a new preclinical study published online October 8 in Cellular & Molecular Immunology by researchers in the Department of Bioscience Technologies at Thomas Jefferson University suggests.

10 Oct 2012

Dexcom receives FDA approval for G4 PLATINUM continuous glucose monitoring system

Dexcom, a leader in continuous glucose monitoring, announced today that the U.S. Food and Drug Administration has approved its eagerly anticipated new continuous glucose monitoring system, the Dexcom G4 PLATINUM.

8 Oct 2012

Hygieia granted CE mark for d-Nav Diabetes Insulin Guidance System

Hygieia, Inc. today announced that the company's d-Nav Diabetes Insulin Guidance System (DIGS) has been granted a CE mark.

8 Oct 2012

MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes

MannKind Corporation today announced that it has completed recruiting patients for two Phase 3 clinical studies of AFREZZA (insulin human [rDNA origin]), an investigational, ultra rapid-acting mealtime insulin therapy, administered using MannKind's to-be-marketed next-generation inhaler.

5 Oct 2012

Paper proposes novel mathematical models for injection of insulin in type 1 and 2 diabetes

Diabetes mellitus is a chronic disease in which individuals exhibit high levels of sugar in the blood, either due to insufficient production of insulin-the hormone that allows glucose to be absorbed by body cells-or the body's lack of response to insulin. Type 1 diabetes occurs due to loss or dysfunction of β-cells of the pancreas, the organ that produces insulin. Type 2 diabetes is caused by a defective glucose-insulin regulatory system.

5 Oct 2012

InsuPad device may improve insulin therapy

A novel device is currently under development for aiding insulin analog therapy in diabetes patients, report researchers.

4 Oct 2012

Hormone therapy offsets adverse metabolic effects of menopause

Long-term hormone therapy helps prevent the adverse metabolic effects that occur following menopause, research shows.

4 Oct 2012

Insulin degludec shows promise in diabetes

Self-administration of daily insulin degludag injections is no less effective than self-injecting insulin glargine in patients with diabetes who are new to insulin therapy, say researchers.

4 Oct 2012

Long-term survivors of hematopoietic cell transplants more likely to develop heart disease

New research appearing online today in Blood, the Journal of the American Society of Hematology (ASH), suggests that long-term survivors of hematopoietic cell transplants (HCT) are at an increased risk of developing heart disease risk factors such as high blood pressure, diabetes, and high cholesterol when compared to the general population.

4 Oct 2012

Estrogen/progesterone treatment started soon after menopause appears safe and effective

Estrogen/progesterone treatment started soon after menopause appears safe and relieves many of the symptoms menopausal women face as well as improving mood and markers of cardiovascular risk, according to a multicenter randomized study presented at the North American Menopause Society (NAMS) Annual Meeting in Orlando, Florida.

4 Oct 2012

Boehringer Ingelheim, Lilly announce data from LY2605541 Phase II study on type 2 diabetes

Eli Lilly and Company and Boehringer Ingelheim today announced patient-reported health outcomes data from a Phase II study of their investigational novel basal insulin analogue, LY2605541, in patients with type 2 diabetes.

3 Oct 2012

New insights on mechanisms involved in regeneration of insulin-producing cells

Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have found that a blood vessel-building gene boosts the ability of human bone marrow stem cells to sustain pancreatic recovery in a laboratory mouse model of insulin-dependent diabetes.

3 Oct 2012

New testing method for gestational diabetes

The increasingly common condition of gestational diabetes can have serious consequences for both the mother and child if left untreated. Prompt diagnosis and therapy can protect against these consequences. A new testing method developed at the MedUni Vienna now makes diagnosis easier and also cheaper.

3 Oct 2012

Low serum levels of IGF-1 and IGFBP-3 associated with Alzheimer's in men

Low serum levels of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) are associated with Alzheimer's Disease in men, but not women, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Oct 2012

Issa threatens to subpoena HHS documents related to Medicare Advantage bonuses

Rep. Darrell Issa, R-Calif., chairman of the House Oversight and Government Reform Committee, alleges that the Department of Health and Human Services is using an $8 billion Medicare bonus payment demonstration project to mask the health law's cuts to Medicare Advantage plans in advance of the election.

29 Sep 2012

Insulin News and Research

Further Reading

Sterile acellular matrices 'reliable in expander-based breast reconstruction'

Scientists resolve new molecular circuit controlling cellular metabolism

New insights into how miR-30d can promote healthy insulin production

Type 2 diabetes screening: an interview with Dr Simon Griffin, MRC Epidemiology Unit at Addenbrooke’s Hospital, Cambridge

First picture of interaction between leptin and its receptor

Recovering Treg cells in pancreatic lymph nodes may restore insulin production in type I diabetics

Dexcom receives FDA approval for G4 PLATINUM continuous glucose monitoring system

Hygieia granted CE mark for d-Nav Diabetes Insulin Guidance System

MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes

Paper proposes novel mathematical models for injection of insulin in type 1 and 2 diabetes

InsuPad device may improve insulin therapy

Hormone therapy offsets adverse metabolic effects of menopause

Insulin degludec shows promise in diabetes

Long-term survivors of hematopoietic cell transplants more likely to develop heart disease

Estrogen/progesterone treatment started soon after menopause appears safe and effective

Boehringer Ingelheim, Lilly announce data from LY2605541 Phase II study on type 2 diabetes

New insights on mechanisms involved in regeneration of insulin-producing cells

New testing method for gestational diabetes

Low serum levels of IGF-1 and IGFBP-3 associated with Alzheimer's in men

Issa threatens to subpoena HHS documents related to Medicare Advantage bonuses

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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