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Antibiotic use may affect efficacy of cancer immunotherapies

Antibiotic use is known to have a near-immediate impact on our gut microbiota and long-term use may leave us drug-resistant and vulnerable to infection.

2 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

Carnegie Mellon to help develop novel camera that peers deep beneath the skin

Carnegie Mellon University is part of a five-year, $10 million program sponsored by the National Science Foundation to develop a new type of camera that peers deep beneath the skin to help diagnose and monitor a wide variety of health conditions.

27 Feb 2018

New NK cell-based immunotherapy effective against several types of leukemia

Researchers at Karolinska Institutet in Sweden have explored NK cell-based immunotherapy on patients with treatment-resistant leukemia. The study, which is published in the scientific journal Clinical Cancer Research, shows that the new therapy is effective against several types of leukemia.

15 Feb 2018

CAR-T therapy saves life of cancer researcher

About a dozen years ago, Dr. Woodring Wright, a UT Southwestern Professor of Cell Biology, sneezed. It broke one of his vertebrae, the interlocking bones that make up the spinal column.

14 Feb 2018

Trial shows safety, feasibility of adding immunotherapy during chemoradiation for head and neck cancer

Analysis of a clinical trial, RTOG Foundation 3504, finds that nivolumab immunotherapy can be administered safely in conjunction with radiation therapy and chemotherapy for patients with newly diagnosed local-regionally advanced head and neck cancers.

13 Feb 2018

GlycoNet researchers to study correlation between sugars and Alzheimer's disease

Two GlycoNet Investigators are using technology to better understand how sugars in the human body are connected to Alzheimer's disease.

12 Feb 2018

Special protein improves survival and lung function of mice with influenza, study shows

GM-CSF, a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza, according to Penn State researchers.

8 Feb 2018

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

A historic study involving researchers from UT Southwestern's Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia (ALL) in children and young adults. The research appears in the New England Journal of Medicine.

1 Feb 2018

Scientists discover the genetic cause of immune disorders

Scientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.

1 Feb 2018

Elevated levels of chlorinated lipids linked to lung injury and death in sepsis patients

In a study published in the Journal of Clinical Investigation Insight, Saint Louis University scientists have found that elevated levels of chlorinated lipids are linked to sepsis, lung injury and death. The finding may offer a way to diagnosis and treat sepsis earlier, saving lives and avoiding serious side effects.

31 Jan 2018

Exposure to e-cigarette flavors can cause inflammation to white blood cells, research finds

Sugar and spice are not so nice, at least when it comes to vaping or inhalation. Exposure to e-cigarette flavoring chemicals and liquids can cause significant inflammation to monocytes, a type of white blood cell -- and many flavoring compounds are also toxic, with cinnamon, vanilla and buttery flavors among the worst.

30 Jan 2018

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery-; successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.

30 Jan 2018

Immune system handles graphene oxide in a way similar to pathogens, study shows

A study by researchers at Karolinska Institutet, the University of Manchester and Chalmers University of Technology published in CHEM shows that our immune system handles graphene oxide in a manner similar to pathogens, paving the way for safer biomedical applications of this two-dimensional material.

27 Jan 2018

GW study uncovers potential obstacle to finding a cure for HIV

The latest "kick-and-kill" research to eliminate the HIV virus uncovered a potential obstacle in finding a cure.

22 Jan 2018

Researchers use immune-mimicking biomaterial scaffolds to fast track T cell therapies

Immunologists and oncologists are harnessing the body's immune system to fight cancers and other diseases with adoptive cell transfer techniques. In a normal immune response, a type of white blood cell known as T cells are instructed by another kind of immune cell called an antigen-presenting cell (APC) to expand their numbers and stay alive.

15 Jan 2018

Researchers discover new weapon to combat tuberculosis

Tuberculosis (TB), an infectious disease which attacks the lungs, claims someone's life every 20 seconds and 1.5 million lives worldwide every year.

11 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Study suggests potential means of stalling or even reversing diabetes-related blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness.

3 Jan 2018

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.

14 Dec 2017