Small Molecules News and Research

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Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Aarthi Narayanan, Assistant Professor, National Center for Biodefense and Infectious Diseases, received $35,000 from Innovation Pharmaceuticals, Inc., for a project in which she is examining the use of Brilacidin for the treatment of coronavirus infections.

5 Jun 2020

Creating hair-bearing human skin becomes a reality

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin--hair, nerves, and fat.

5 Jun 2020

Study: MafB protein may protect against renal failure

Focal segmental glomerulosclerosis (FSGS) is a common cause of steroid-resistant nephrotic syndrome, a type of kidney disease that is accompanied by massive urinary protein loss and that may progress to end-stage renal disease.

5 Jun 2020

Natural molecules that stimulate dopamine production may help reverse Parkinson's disease

Investigators have identified two molecules naturally produced by the body that stimulate the production of dopamine, the molecule that is in short supply in the brains of patients with Parkinson's disease.

4 Jun 2020

New device shows cigarette alternatives may be more hazardous than revealed by manufacturer testing

A more sensitive technique shows cigarette alternatives may be more hazardous than manufacturer testing had found.

4 Jun 2020

Small protein has a large impact on bacterial gene regulation

Meningococci are bacteria that can cause life-threatening meningitis and sepsis. These pathogens use a small protein with a large impact: The RNA-binding protein ProQ is involved in the activation of more than 250 bacterial genes.

4 Jun 2020

New platform can speed up the development of novel antibiotics

Harmful bacteria react less and less to common antibiotics. The infections they cause are therefore increasingly deadly.

4 Jun 2020

Bruker introduces breakthrough MALDI-2 source on timsTOF fleX, and further innovations in CCS-enabled 4D proteomics on timsTOF

At the virtual ASMS 2020 Reboot conference, Bruker Corporation today announces a major advance in matrix-assisted laser desorption ionization (MALDI) with the launch of the world’s first commercial MALDI-2 post-ionization (PI) source, which is now available as an option on the timsTOF fleXTM ESI/MALDI mass spectrometer.

From Bruker Life Sciences Mass Spectrometry 3 Jun 2020

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

A new generation, high resolution mass spectrometer (MS) is designed to give proteomics, metabolomics, biopharmaceutical characterization and small-molecule scientists the analytical performance required for research and high-throughput analyses.

From Thermo Fisher Scientific Inc. 28 May 2020

UZH researchers develop new X-ray contrast agent for high-resolution vascular imaging

Various diseases in humans and animals - such as tumors, strokes or chronic kidney disease - damage the blood vessels. Capillaries, the smallest blood vessels in the body, are particularly affected.

26 May 2020

Cancer biologists identify important drivers of tumor resistance

Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies.

18 May 2020

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

University of Greenwich develops compounds that can fight COVID-19 killer

Covid-19 treatment that could potentially also help protect cancer and organ transplant patients is being developed at the University of Greenwich.

15 May 2020

Sanford director receives major grant to advance broad-spectrum antivirals for respiratory diseases

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce that Sumit Chanda, Ph.D., has received a $10.2 million, four-year grant from the Department of Defense to develop and advance broad-spectrum antivirals for respiratory diseases.

12 May 2020

New breakthrough in chemistry could accelerate drug development

Scientists have successfully developed a new technique to reliably grow crystals of organic soluble molecules from nanoscale droplets, unlocking the potential of accelerated new drug development.

8 May 2020

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

In recognition of his high-impact work advancing the field of RNA-targeting medicines, the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, has awarded Scripps Research Chemistry Professor Matthew Disney, PhD, a prestigious Research Program Award, to aid Disney's development of treatments for incurable diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.

4 May 2020

Small Molecules News and Research

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Creating hair-bearing human skin becomes a reality

Study: MafB protein may protect against renal failure

Natural molecules that stimulate dopamine production may help reverse Parkinson's disease

New device shows cigarette alternatives may be more hazardous than revealed by manufacturer testing

Small protein has a large impact on bacterial gene regulation

New platform can speed up the development of novel antibiotics

Bruker introduces breakthrough MALDI-2 source on timsTOF fleX, and further innovations in CCS-enabled 4D proteomics on timsTOF

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

UZH researchers develop new X-ray contrast agent for high-resolution vascular imaging

Cancer biologists identify important drivers of tumor resistance

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

University of Greenwich develops compounds that can fight COVID-19 killer

Sanford director receives major grant to advance broad-spectrum antivirals for respiratory diseases

New breakthrough in chemistry could accelerate drug development

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

ProteoGenix launches first Human Immune COVID-19 antibody library

Albany, Wisconsin researchers look for molecular clues to fight COVID-19

Study marks a major step towards beta cell replacement therapy

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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