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The liver may produce most of the body's good cholesterol

Research in mice suggests that the liver may produce most of the body's "good" cholesterol, an unexpected finding that might one day help scientists develop new treatments to raise levels of this heart-protecting molecule in humans.

10 Apr 2005

Three out of every four adults over age 50 use some kind of alternative medicine

This study found that 71 percent of older adults used some form of alternative medicine in 2000. A study done in 2002, found a lower rate -- about 62 percent – among all adults.

10 Apr 2005

First identified gene to link autoimmune diseases with cardiovascular diseases

A common gene variant has been identified as the risk factor behind a number of common diseases by research scientists at Karolinska Institutet and the Centre for Molecular Medicine (CMM), Stockholm, Sweden. Up to a quarter of the population could be affected.

10 Apr 2005

Teens feel most stress before HIV-infected parent dies

A UCLA AIDS Institute study has discovered that teens of HIV-infected parents are at the highest risk for depression and self-destructive behavior before their parent's death, not after. Published in the April issue of the Journal of Consulting and Clinical Psychology, the findings emphasize the importance of providing support services to HIV-affected families promptly after a parent's diagnosis and through the subsequent illness — not only after the parent's death.

7 Apr 2005

Race to market cancer vaccine

In a race to market the first vaccine against the virus that causes cervical cancer and genital warts drug manufacturers Merck & Co Inc. and GlaxoSmithKline plc are in head-to-head competition.

7 Apr 2005

Pfizer separately agrees to suspend sales of Bextra due to FDA evaluation of risks of rare but serious skin reactions

Pfizer said today it will work with the U.S. Food and Drug Administration (FDA) to add expanded risk information in the Celebrex label following an FDA decision announced this morning to require boxed warnings of potential cardiovascular risk for all COX-2 pain relievers and all NSAIDs, including older non-specific drugs such as ibuprofen and naproxen.

7 Apr 2005

Animi-3 may offer hope for rheumatoid arthritis

Animi-3, a prescription medication from PBM Pharmaceuticals, Inc., contains ingredients that may have a beneficial, protective effect in inflammatory diseases such as rheumatoid arthritis (RA).

7 Apr 2005

Belgian doctors treating critically ill infants favour legalising euthanasia

Most paediatricians in Flanders, Belgium, favour the legalisation of lethal drugs to end the life of some critically ill babies and infants, concludes a study in this week’s issue of The Lancet.

7 Apr 2005

Use of smokeless tobacco helped hard-to-quit smokers give up their habit

The study, published in the January-March issue of the Journal of Psychoactive Drugs, reports on subjects who were contacted seven years after completion of a smoking cessation program that replaced cigarettes with smokeless tobacco products as a harm-reduction strategy.

7 Apr 2005

Pfizer withdraws Bextra from market

Despite an expert panel stating last month that the three COX-2 drugs Vioxx, Bextra and Celebrex were safe enough to be marketed, the U.S. Food and Drug Administration (FDA) has this week told drug manufacturer Pfizer to remove the drug Bextra from the market and a statement by Pfizer confirms that the European Union regulators have done the same.

7 Apr 2005

Research helps understand how the malaria parasite disguises itself to avoid detection by the immune system

Scientists are making strides in understanding how the malaria parasite Plasmodium falciparum disguises itself to avoid detection by the immune system. The findings could lead to the development of new drugs for a disease that causes more than 300 million acute illnesses and at least one million deaths each year, most of them in developing countries.

7 Apr 2005

Naltrexone combined with psychotherapy helps treat alcohol dependence

Long-acting injections of the drug naltrexone, combined with psychotherapy, significantly reduced heavy drinking in patients being treated for alcohol dependence, according to a study in the Journal of the American Medical Association by a Yale School of Medicine researcher.

7 Apr 2005

Role of oxidative stress (OS) in dialysis patients

An article published in Hemodialysis International discusses the role of oxidative stress (OS) in dialysis patients, an imbalance which can result in long-term health problems. Potential therapeutic options to restore balance in patients are also reviewed.

7 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Study may lead to a better understanding of how antidepressants like Prozac work

According to results published in today's issue of the journal Neuron, a study in mice proposes that dopamine and serotonin neurotransmitter systems in the brain occasionally get their signals crossed, causing delays in stabilizing mood.

7 Apr 2005

Process called sumoylation regulates key ion channel

Researchers at the University of Chicago have found that a recently discovered biological process known as sumoylation -- until now thought to be active only in the nucleus -- also occurs near the cell's surface where it regulates at least one and possibly many kinds of proteins, providing a novel target for the development of new drugs.

7 Apr 2005

Staph superbug now far more common in the community

Two teams of experts are saying that a drug-resistant "superbug" previously only found in hospitals is becoming more common in the community and must be aggressively treated. They say that staphylococcus aureus, or staph, infections that are resistant to methicillin and similar drugs can now be put into the category of flesh-eating bacteria and doctors need to be aware of this and exchange antibiotics at the first sign of trouble.

6 Apr 2005

Promising new treatment for alcohol dependence

According to the World Health Organization's Global Burden of Disease project, alcohol dependence, a major public health problem, ranks fourth as one of the worlds leading cause of disability. In the US alone over 100,000 deaths each year, where alcohol was a contributing factor, could have been prevented.

6 Apr 2005

Osteoporosis drug reduces women's risk of mild cognitive impairment

A drug prescribed for the prevention of osteoporosis reduced women's risk of mild cognitive impairment by 33 percent in a worldwide clinical trial led by researchers at San Francisco VA Medical Center (SFVAMC).

6 Apr 2005

Contrary to common wisdom, sleeping pills may not increase fall risk

In nursing homes across the country, elderly people with insomnia often go untreated, because of the perception that sleeping pills increase the risk of falls and injuries that are a bane of old age.

6 Apr 2005