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Common epigenetic problem doubles cancer risk

In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there.

27 Feb 2005

Pfizer acquires Idun Pharmaceuticals

Pfizer today announced that it has entered into an agreement to acquire Idun Pharmaceuticals, a biopharmaceutical company focused on the discovery and development of therapies to control apoptosis, a process of cell death that occurs in a broad range of diseases.

24 Feb 2005

$71 million to launch a new drug

Mid-level pharmaceutical brands invest an average of $71 million in marketing between Phase III trials and the first year on the market, according to a new report from Cutting Edge Information.

24 Feb 2005

Protein called CK2 plays a deadly role in colorectal carcinoma

A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body. This finding, by researchers at St. Jude Children's Research Hospital, is currently published in the online edition of Oncogene.

24 Feb 2005

Mathematical model describes the electrical storm that rages during a brain seizure

"We're trying to get to the underlying state of the brain that leads to these seizures," said Mark Kramer, a Ph.D. student in UC Berkeley's Applied Science and Technology Program and lead author of the paper. "Our hope is that the model can highlight potential areas where a seizure can be stopped."

24 Feb 2005

Common clinical problem, Rosacea

A number of clinical symptoms and signs are included under the broad group Rosacea. Facial flushing, the appearance of broken blood vessels and persistent redness of the face, eruption of inflamed spots & pimples, on the face and thickening of the sebaceous glands of the nose, with swelling & congestion in that area.

24 Feb 2005

Sir Bobby Robson opens state-of-the-art research centre

Cancer survivor Sir Bobby Robson marked the official opening of a state-of-the-art research centre by meeting the doctors and scientists using its facilities to help patients.

23 Feb 2005

Need for greater understanding of shingles

Results from a recent international survey reveal that most people are aware of herpes zoster -- more commonly known as shingles -- but do not truly understand the complexity of the condition or the potential impact it has on their overall health.

23 Feb 2005

Taipan venom used as a new drug to treat heart failure

A venom component from the Taipan, the world’s deadliest snake, is being developed by Brisbane biotechnology company ElaCor, as a new drug to treat heart failure.

23 Feb 2005

Researchers identify target for cancer drugs

For nearly a decade, scientists have been trying to fully understand a particular communication pathway inside of cells that contributes to many malignant brain and prostate cancers. While scientists have identified elements of this pathway, other key components have remained a mystery.

23 Feb 2005

Biggest-ever study of constipation in the world

An embarrassing medical problem that costs UK health services £50m each year is to be investigated in the biggest-ever study of the condition in the world.

23 Feb 2005

Feverfew or Bachelor's Button, kills human leukemia stem cells like no other single therapy

A daisy-like plant known as Feverfew or Bachelor's Button, a traditional remedy for reducing fevers and a treatment for nervousness, hysteria and low spirits, is the source of an agent that kills human leukemia stem cells like no other single therapy

23 Feb 2005

Short-term use of selective COX-2 inhibitors may be safe for patients with cirrhosis of the liver

Short-term use of selective COX-2 inhibitors may be safe for patients with cirrhosis of the liver, according to a recent study that compared the effects of celecoxib, naproxen, and a placebo on cirrhotic patients in a double-blind randomized controlled study.

22 Feb 2005

Research shows preventive effects of cannabinoids on Alzheimer's disease

New research shows that a synthetic analogue of the active component of marijuana may reduce the inflammation and prevent the mental decline associated with Alzheimer's disease.

22 Feb 2005

Don’t believe everything you read on diets

In a society increasingly fixated with body image, we are bombarded with so-called scientific evidence promoting the use of a myriad of diets.

22 Feb 2005

2.5 million euros helps fight liver cancer

The overall project will concentrate on three areas where Europe is in a relatively favourable position compared with the US - human tissue resources, ribonucleic acid (RNA) technology, and structural proteomics. However, the initial focus will be on the development of genomics targets in hepatocellular carcinoma (HCC) or liver cancer as it is one of the leading causes of cancer death worldwide and has a very poor prognosis.

22 Feb 2005

Early diagnosis and treatment is important for children and adolescents with bipolar disorder

"These new guidelines were formulated by a group of leading experts in child psychiatry and are the most up-to-date and comprehensive set of guidelines for the treatment of children and adolescents with bipolar disorder," said Dr. Kowatch. "They represent a major step towards practicing evidence-based medicine in this difficult to treat group of patients.

22 Feb 2005

State-of-the-art computer technology to tackle deadly diseases such as influenza

Researchers at the University of Bath have won a £261,000 grant to use the latest software to produce a blueprint of a designer drug that could stop influenza and some other diseases from replicating in humans.

22 Feb 2005

When breast augmentation or reduction cases are medically necessary

Traditionally, breast augmentation and reduction surgeries are defined by health insurers as cosmetic. It's a definition that often puts patients at odds with health insurers. Payers have difficulty deciding if breast augmentation or reduction cases are medically necessary.

22 Feb 2005

Prospects for a safe, effective AIDS vaccine are improving

Prospects for a safe, effective AIDS vaccine are improving as researchers from the public and private sectors begin to collaborate in new and creative ways, researchers said recently at the 2005 Annual Meeting of the American Association for the Advancement of Science (AAAS).

22 Feb 2005