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Methylphenidate linked to chromosomal changes

In a small but startling preliminary new study, Texas researchers have found that after just three months, every one of a dozen children treated for attention deficit/hyperactivity disorder (ADHD) with the drug methylphenidate experienced a threefold increase in levels of chromosome abnormalities—occurrences associated with increased risks of cancer and other adverse health effects.

27 Feb 2005

28 percent of injecting drug users acquired their needles from safe sources

Nearly half of injection drug users disposed of their used syringes safely, yet only 28 percent acquired their needles from safe sources, according to a study of injection drug users in Baltimore, Md., conducted by researchers at the Johns Hopkins Bloomberg School of Public Health.

27 Feb 2005

Early Alzheimer's disease may be precipitated by a neuron traffic jam

Early Alzheimer's disease may be precipitated by a “traffic jam” within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers.

27 Feb 2005

New York City Health statement on rare strain of HIV in a New York City resident

On February 11, 2005, the New York City Department of Health and Mental Hygiene (DOHMH) reported a case of HIV infection with a strain that is resistant to many drugs in three classes of HIV medications, and which appears to have progressed to AIDS within 4 to 20 months after infection.

27 Feb 2005

Americans believe drug industry cares more about profits than people

Americans believe prescription drugs are improving their lives, but most also say that the drug industry cares more about profits than people, according to the latest Kaiser Health Poll Report issued by the Kaiser Family Foundation.

27 Feb 2005

Second-generation Antidepressants

A recent article in the prestigious British Medical Journal seems to confirm an increased risk for suicidal behavior among adults taking popular antidepressants. This follows evidence that certain selective serotonin reuptake inhibitors (SSRIs) may have a similar effect among children and adolescents.

27 Feb 2005

NIH awards grant to explore causal relationship between epoetin dose and survival of hemodialysis patients

The National Institutes of Health, National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) has awarded a two-year grant to the Medical Technology and Practice Patterns Institute (MTPPI) in collaboration with Harvard School of Public Health (HSPH) to explore the causal relationship between epoetin dose and survival of hemodialysis patients receiving this therapy.

27 Feb 2005

Common epigenetic problem doubles cancer risk

In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there.

27 Feb 2005

Pfizer acquires Idun Pharmaceuticals

Pfizer today announced that it has entered into an agreement to acquire Idun Pharmaceuticals, a biopharmaceutical company focused on the discovery and development of therapies to control apoptosis, a process of cell death that occurs in a broad range of diseases.

24 Feb 2005

$71 million to launch a new drug

Mid-level pharmaceutical brands invest an average of $71 million in marketing between Phase III trials and the first year on the market, according to a new report from Cutting Edge Information.

24 Feb 2005

Protein called CK2 plays a deadly role in colorectal carcinoma

A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body. This finding, by researchers at St. Jude Children's Research Hospital, is currently published in the online edition of Oncogene.

24 Feb 2005

Mathematical model describes the electrical storm that rages during a brain seizure

"We're trying to get to the underlying state of the brain that leads to these seizures," said Mark Kramer, a Ph.D. student in UC Berkeley's Applied Science and Technology Program and lead author of the paper. "Our hope is that the model can highlight potential areas where a seizure can be stopped."

24 Feb 2005

Common clinical problem, Rosacea

A number of clinical symptoms and signs are included under the broad group Rosacea. Facial flushing, the appearance of broken blood vessels and persistent redness of the face, eruption of inflamed spots & pimples, on the face and thickening of the sebaceous glands of the nose, with swelling & congestion in that area.

24 Feb 2005

Sir Bobby Robson opens state-of-the-art research centre

Cancer survivor Sir Bobby Robson marked the official opening of a state-of-the-art research centre by meeting the doctors and scientists using its facilities to help patients.

23 Feb 2005

Need for greater understanding of shingles

Results from a recent international survey reveal that most people are aware of herpes zoster -- more commonly known as shingles -- but do not truly understand the complexity of the condition or the potential impact it has on their overall health.

23 Feb 2005

Taipan venom used as a new drug to treat heart failure

A venom component from the Taipan, the world’s deadliest snake, is being developed by Brisbane biotechnology company ElaCor, as a new drug to treat heart failure.

23 Feb 2005

Researchers identify target for cancer drugs

For nearly a decade, scientists have been trying to fully understand a particular communication pathway inside of cells that contributes to many malignant brain and prostate cancers. While scientists have identified elements of this pathway, other key components have remained a mystery.

23 Feb 2005

Biggest-ever study of constipation in the world

An embarrassing medical problem that costs UK health services £50m each year is to be investigated in the biggest-ever study of the condition in the world.

23 Feb 2005

Feverfew or Bachelor's Button, kills human leukemia stem cells like no other single therapy

A daisy-like plant known as Feverfew or Bachelor's Button, a traditional remedy for reducing fevers and a treatment for nervousness, hysteria and low spirits, is the source of an agent that kills human leukemia stem cells like no other single therapy

23 Feb 2005

Short-term use of selective COX-2 inhibitors may be safe for patients with cirrhosis of the liver

Short-term use of selective COX-2 inhibitors may be safe for patients with cirrhosis of the liver, according to a recent study that compared the effects of celecoxib, naproxen, and a placebo on cirrhotic patients in a double-blind randomized controlled study.

22 Feb 2005