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Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

Results of a randomised trial in this week’s issue of THE LANCET highlight how the low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries to help reduce illness and death from opportunistic infections such as pneumonia.

18 Nov 2004

New antidotes for organophosphates are needed to prepare for chemical attacks in the West

Organophosphates are a group of organic compounds containing phosphorus, some of which are used as pesticides. Organophosphates have also been used in chemical weapons and nerve gas attacks, such as the sarin attack in Japan.

18 Nov 2004

Acupuncture better than drugs alone for osteoarthritis of the knee

Acupuncture, as a complementary therapy to drug treatment for osteoarthritis of the knee, is more effective than drug treatment alone, find researchers from Spain in this week's BMJ.

18 Nov 2004

New findings have implications for chronic use of COX-2 Inhibitors in pre-menopausal women

Heart disease is less pronounced in women than in men as humans age, but this difference narrows after menopause. Some studies have shown that estrogen slows heart disease in mouse models, but the mechanism is largely unknown.

18 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Not only are breast enhancement pills unproven, they could be dangerous

Flip through any women's magazine and you are sure to find advertisements hawking pills to enlarge women's breasts. But do these pills actually work? Probably not, says the American Society of Plastic Surgeons (ASPS).

18 Nov 2004

FDA clarifies it's position on Vioxx

For the past several weeks, various allegations and characterizations have circulated and been reported on regarding FDA's approval and post market review of the drug Vioxx, a "Cox-2 inhibitor," that its sponsor, Merck, voluntarily withdrew from the market September 30th, 2004.

17 Nov 2004

Children throughout the world are increasingly being prescribed antidepressants

Children throughout the world are increasingly being prescribed antidepressants and other drugs designed to calm or stimulate the brain, finds research in Archives of Disease in Childhood. Prescription rates increased the most in the UK, the research suggests.

17 Nov 2004

Canadian prescription drugs

Canadian pharmacies that mail prescription drugs to U.S. patients have been backed into a no-win situation by the Canadian government and the provincial medical and pharmacy associations.

16 Nov 2004

FDA commits to use of radio frequency identification (RFID) technology

The U.S. Food and Drug Administration (FDA) is stepping up its efforts to improve the safety and security of the nation's drug supply through the use of radio frequency identification (RFID) technology.

16 Nov 2004

Startling new blood pressure findings - atherosclerosis slowed

A new study led by The Cleveland Clinic shows that giving blood pressure lowering medication to heart disease patients with a “normal” blood pressure dramatically reduces risk of adverse cardiac events and slows disease progression.

16 Nov 2004

Troponin genes offer new insights to familial heart failure

Mutations in the troponin protein complex may be useful for predicting the course of heart failure due to dilated cardiomyopathy and also for guiding treatment and research, according to a new study in the Nov. 16, 2004 issue of the Journal of the American College of Cardiology.

16 Nov 2004

Keeping fit lowers C-Reactive protein in people with metabolic syndrome

In people with signs of metabolic syndrome, including high blood pressure, high triglycerides, high cholesterol, elevated blood glucose and obesity, physical activity appears to reduce a marker for inflammation which has been linked to heart disease

16 Nov 2004

Large increase in male mentally ill drug abusers

The amount of mentally ill male drug abusers has increased by more than 79% in five years across England and Wales, finds research in the Journal of Epidemiology and Community Health.

16 Nov 2004

World’s strongest acid may have a role in synthesizing pharmaceuticals

Researchers at the University of California, Riverside have discovered the world’s strongest acid. Remarkably it is also the gentlest acid. This non-toxic and non-corrosive acid may have a role in processes such as improving the quality of gasoline, developing polymers and synthesizing pharmaceuticals.

16 Nov 2004

Discovery of new compounds that may treat mucus build-up associated with cystic fibrosis

Preliminary studies show these compounds improve the flow of mucus through the respiratory tract, allowing airways to clear more quickly and efficiently.

14 Nov 2004

36% of cancer patients ages 65 and older participate in clinical trials

A new study finds that only 36% of cancer patients ages 65 and older participate in clinical trials, despite making up 60% of the U.S. cancer population. The study will be published November 15 in the Journal of Clinical Oncology (JCO).

14 Nov 2004

Hysteroscopic sterilization will save patients money compared to laparoscopic tubal ligation

Mayo Clinic gynecologists have discovered that hysteroscopic sterilization, a new method of plugging the fallopian tubes to prevent conception, will save patients money compared to laparoscopic tubal ligation, the most commonly used method of sterilization for women.

14 Nov 2004

Use of the drug etodolac instead of drugs like Celebrex or Bextra could save $40 million annually

People in search of pain relief who take the generic anti-inflammatory etodolac suffer 60 percent fewer gastrointestinal complications than those who take similar drugs, according to researchers at UT Southwestern Medical Center at Dallas and the Dallas Veterans Affairs Medical Center.

14 Nov 2004

Can poor countries help rich countries contain drug costs?

Rich countries could follow the lead of poor countries and adopt a more systematic way of selecting medicines for reimbursement, according to a paper in this week's BMJ.

14 Nov 2004