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Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Researchers from the Johns Hopkins Kimmel Cancer Center, Indiana University and the University of Michigan have found that some women have a gene mutation that may decrease the effectiveness of tamoxifen, a commonly used breast cancer drug.

7 Jun 2004

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

A chemotherapy regimen commonly used to treat non-small cell lung cancer is both more effective and more toxic in Japanese patients than in American patients, researchers reported Saturday at the annual meeting of the American Society of Clinical Oncologists.

7 Jun 2004

Atrasentan reduces cancer risk by 20 percent in men with advanced hormone-resistant prostate cancer

Recent clinical studies led by Johns Hopkins Kimmel Cancer Center researchers have found that a drug called atrasentan reduces the risk by 20 percent that cancer will progress in men with advanced hormone-resistant prostate cancer.

7 Jun 2004

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

A biological agent — a drug that wraps vitamin A inside bubbles of fat — used without chemotherapy appears to offer as many as one-third of patients with a rare form of leukemia an opportunity for a long-term, disease-free future, say researchers at The University of Texas M. D. Anderson Cancer Center.

7 Jun 2004

Herceptin shows real promise in treatment of HER-2 positive breast disease

According to a study conducted at The University of Texas M. D. Anderson Cancer Center, more than twice as many women with early stage, HER-2 positive breast disease who received Herceptin as part of their pre-surgery chemotherapy had their tumors completely disappear compared to like patients who received only chemotherapy.

7 Jun 2004

Serum estrogen receptor modulator's (SERM's) may help reduce postmenopausal breast cancer risk

Newest research findings were presented on the possible benefits they may provide for postmenopausal breast cancer risk reduction. SERMs are a class of drugs that can block the cell's ability to use estrogen to stimulate the development of breast cancer.

7 Jun 2004

Australian scientists have developed a tool that acts as a pregnancy test for the detection of anthrax

Once a deadly disease associated with animals, anthrax is now used as a bioterrorist weapon. While infection can be controlled with antibiotics, in a bioterrorism attack people will not know they have been infected until symptoms develop, at which stage drugs are useless.

7 Jun 2004

Australia's CSIRO to exhibit major display at the world's largest biotechnology conference

CSIRO is mounting a major display of technologies this week at BIO 2004, the world's largest biotechnology conference, being held in San Francisco, USA, from 6-9 June.

7 Jun 2004

Gemcitabine may help breast cancer patients with advanced disease live longer

Breast cancer patients with advanced disease live longer when treated with a new drug, gemcitabine, in combination with paclitaxel, a traditional drug, according to results of a landmark global phase III study presented today at the American Society of Clinical Oncology (ASCO) annual meeting.

6 Jun 2004

Velcade major improvement over standard therapy for relapsed multiple myeloma

Early results from a major, international Phase III clinical trial decisively show that recurrent multiple myeloma is more effectively treated with the drug bortezomib (trade name: Velcade TM) than with dexamethasone, a drug that for decades has been the standard therapy for relapsed disease, researchers at Dana-Farber Cancer Institute report.

6 Jun 2004

Exenatide shows significant improvements in glucose control for people With type 2 diabetes

Amylin Pharmaceuticals, Inc., and Eli Lilly and Company have presented detailed 30-week data from two of the three pivotal Phase 3 studies of exenatide during a late-breaking session at the American Diabetes Association's (ADA) 64th Scientific Sessions in Orlando, Florida.

5 Jun 2004

Five major prescription drug manufacturers make drugs available to Medicare discount cardholders

The Pharmacy Care Alliance (PCA) today announced that AstraZeneca, Johnson & Johnson Pharmaceutical Companies, Inc., Eli Lilly and Company, Merck and Novartis will make many prescription drugs available to qualifying PCA Medicare discount cardholders free of charges from the manufacturer plus a nominal amount to cover dispensing, processing and other costs.

5 Jun 2004

Democrats air their views on Medicare prescription drugs discount cards

On Tuesday the new Medicare prescription drugs discount cards went into effect. The enrollment process is so confusing, most seniors are not signing up for the cards. Those that have will quickly discover the cards don’t deliver the savings they were promised.

3 Jun 2004

China launches nationwide campaign to urge the public to take medicine in a safe way

China on Thursday launched a nationwide campaign to urge the public to take medicine in a safe way, in a bid to reduce increasing damages from excessive and inappropriate drug taking.

3 Jun 2004

Adrenaline packs a powerful punch in the use of antidepressants

Researchers from the University of Pennsylvania School of Medicine found that norepinephrine (adrenaline) plays an important role in animals in determining behavioral effects in some of the most commonly prescribed antidepressants, regardless of which biochemical pathway the drug uses to alleviate symptoms of depression.

3 Jun 2004

Lack of funding and staff in the UK hinders patient care

Doctors across the UK are leading innovative approaches to patient care but are blocked from developing their projects further by lack of funding and staff according to a new publication launched today (3 June) by the BMA.

3 Jun 2004

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Bone marrow stem cells, when exposed to damaged liver tissue, can quickly convert into healthy liver cells and help repair the damaged organ, according to new research from the Johns Hopkins Kimmel Cancer Center.

2 Jun 2004

Innovative type of brain scan can determine where blockages of blood to the brain lie

It's a no-brainer that the brain needs a constant supply of blood to keep it going. But some medical conditions can block or reduce that life-giving flow. Whether it's a stroke, a clogged artery or a brain tumor, any situation where blood can't get to the whole brain can lead to death or permanent disability.

2 Jun 2004

Study may help oncologists tailor chemotherapy to patients based on their genetic make-up

Genetic variations in an individual’s ability to repair DNA damage may help predict survival in lung cancer patients treated with the common chemotherapy drugs cisplatin or carboplatin, a new study shows.

2 Jun 2004

Model of the central nervous system will allow oncologists and neurosurgeons to target tumours more effectively

A larger-than-life model of the human central nervous system including the brain and spinal cord, which will allow oncologists and neurosurgeons to target tumours more effectively, will be among a range of student projects on display at an event at The University of Nottingham this week.

2 Jun 2004

Drugs News and Research

Gene mutation found in some women may decrease effectiveness of tamoxifen breast cancer drug

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

Atrasentan reduces cancer risk by 20 percent in men with advanced hormone-resistant prostate cancer

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

Herceptin shows real promise in treatment of HER-2 positive breast disease

Serum estrogen receptor modulator's (SERM's) may help reduce postmenopausal breast cancer risk

Australian scientists have developed a tool that acts as a pregnancy test for the detection of anthrax

Australia's CSIRO to exhibit major display at the world's largest biotechnology conference

Gemcitabine may help breast cancer patients with advanced disease live longer

Velcade major improvement over standard therapy for relapsed multiple myeloma

Exenatide shows significant improvements in glucose control for people With type 2 diabetes

Five major prescription drug manufacturers make drugs available to Medicare discount cardholders

Democrats air their views on Medicare prescription drugs discount cards

China launches nationwide campaign to urge the public to take medicine in a safe way

Adrenaline packs a powerful punch in the use of antidepressants

Lack of funding and staff in the UK hinders patient care

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Innovative type of brain scan can determine where blockages of blood to the brain lie

Study may help oncologists tailor chemotherapy to patients based on their genetic make-up

Model of the central nervous system will allow oncologists and neurosurgeons to target tumours more effectively

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