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Regeneration ability may lie with the body's innate immune system, study shows

The answer to regenerative medicine's most compelling question -- why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot -- may lie with the body's innate immune system, according to a new study of heart regeneration in the axolotl, or Mexican salamander, an organism that takes the prize as nature's champion of regeneration.

21 Sep 2017

Researchers identify natural protective factor against chronic inflammation in diabetes patients

In type 2 diabetes, chronic inflammation drives cardiovascular disease, the leading cause of death among people with the condition. Researchers at Joslin Diabetes Center now have identified an unexpected natural protective factor that works against this inflammation.

20 Sep 2017

Modified blood thinner may be first promising method to prevent repercussions after TBI

A chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows traumatic brain injury (TBI), according to new research findings.

13 Sep 2017

Researchers set new delivery distance record for medical drones

Johns Hopkins researchers have set a new delivery distance record for medical drones, successfully transporting human blood samples across 161 miles of Arizona desert. Throughout the three-hour flight, they report, the on-board payload system maintained temperature control, ensuring the samples were viable for laboratory analysis after landing.

12 Sep 2017

Antibody therapy found effective in subgroup of patients with treatment-resistant COPD

An antibody treatment reduces the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant chronic obstructive pulmonary disease (COPD), according to the results of two large international trials presented today at the European Respiratory Society International Congress in Milan, Italy, and simultaneously published in the New England Journal of Medicine.

12 Sep 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

FDA grants accelerated approval to new treatment for children with Chagas disease

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

29 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

$FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL$

FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL

The U.S. Food and Drug Administration today approved Besponsa (inotuzumab ozogamicin) for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).

17 Aug 2017

Antibiotic use makes immune cells less effective in fighting infections

Adding another reason for doctors to avoid the overuse of antibiotics, new research shows that a reduction in the variety of microbes in the gut interferes with the immune system's ability to fight off disease.

17 Aug 2017

Researchers discover way to stop deadly fungus from spreading to the brain

Research led by the University of Birmingham has discovered a way to stop a deadly fungus from 'hijacking' the body's immune system and spreading to the brain.

16 Aug 2017

Congress revamps housing program to benefit areas where HIV is spreading

In a bipartisan push, Congress has restructured a federal program that provides housing assistance for people living with HIV to funnel more money into areas struggling to control the outbreak.

7 Aug 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

Ocular microbiome trains developing immune system to ward off pathogens, study shows

Bugs in your eyes may be a good thing. Resident microbes living on the eye are essential for immune responses that protect the eye from infection, new research shows.

11 Jul 2017

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs.

28 Jun 2017

The new war on sepsis

Dawn Nagel, a nurse at St. Joseph Hospital in Orange, Calif., knew she was going to have a busy day, with more than a dozen patients showing signs of sepsis.

21 Jun 2017

Genetic mutation could be cause of severe eczema, research finds

A genetic mutation could be the cause of severe eczema, according to new research published June 19 in Nature Genetics by researchers at the Uniformed Services University of the Health Sciences.

20 Jun 2017

New mathematical model predicts growth and progression of HIV in the brain

After uncovering the progression of HIV infection in the brain thanks to a new mathematical model developed by a UAlberta research team, clinicians and researchers are developing a nasal spray to administer drugs more effectively.

20 Jun 2017

JHH Nutrition Score can help quickly identify heart surgery patients at risk for malnutrition

Patients who are at risk for malnutrition when undergoing heart surgery now can be more quickly and easily identified, leading to intervention and potentially better surgical outcomes, according to a study published online today in The Annals of Thoracic Surgery.

15 Jun 2017

New cancer drug shows promise to treat leukemia in mouse models

Almost 6,000 new cases of acute lymphoblastic leukemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.

9 Jun 2017