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A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

When a fall, car crash, bullet, or knife crushes or cuts a spinal cord, the injury does not stop there. Rather, tissues continue to discharge toxic chemicals for hours, even days and weeks. These chemicals kill and disable nerve cells some distance away from the core injury, compounding the damage and making rehabilitation more difficult or impossible.

26 Mar 2004

Oral medication for diabetes a step closer

University of Toronto researchers have shown that "designer molecules" can interact with the body's insulin receptor, a step toward the development of an oral medication for diabetes. U of T professors Lakshmi Kotra, Cecil Yip, Peter Ottensmeyer and Robert Batey have created the first small molecules using the three-dimensional structure of the insulin receptor. A receptor is the site on the surface of a cell to which molecules with specific tasks, such as hormones, attach themselves. Insulin's task is to initiate the utilization of sugar in the blood.

26 Mar 2004

Children with sickle cell disease are living longer, dying less often from their disease

Children with sickle cell disease, an inherited red blood-cell disorder, are living longer, dying less often from their disease and contracting fewer fatal infections than ever before, researchers at UT Southwestern Medical Center at Dallas report. Their study, which will appear in the June edition of the scientific journal Blood, is the first to evaluate survival rates of children receiving the most modern treatments for sickle cell disease. It's also one of the largest published sickle cell studies to date. Researchers followed more than 700 Dallas-area children with the disease over two decades.

25 Mar 2004

British company to launch "super bug tester" into UK hospitals

MRSA is the first test to be developed from Acolyte’s BacLite® testing platform. BacLite reduces the time for identifying both the type of bacteria and, more importantly, the antibiotic sensitivity of the bacteria from the current 3-4 day standard to just 2-5 hours. This time advantage will mean clinicians will be able to treat, much more effectively, serious bacterial infections and prevent potentially fatal complications, such as sepsis and septic shock, from developing.

24 Mar 2004

Ban Chlorpyrifos and Diazinonon Impacts Child Birth Weights

A federal ban on two insecticides has resulted in a significant reduction in their impact on newborns' birth weight and length, according to a new study funded by the National Institute of Environmental Health Sciences of the National Institutes of Health, the U.S. Environmental Protection Agency, and other private foundations.

23 Mar 2004

New Australian Research into Autism and Asperger's Disorder

Researchers at Sydney University are recruiting volunteers for an investigation that will help improve our understanding of young people with High Functioning Autism and Asperger's Disorder.

23 Mar 2004

20% of worldwide population lack enough zinc in diet

Up to one-fifth of the world's people lack sufficient zinc in their diet, while an estimated one-third live in countries considered at high risk of zinc deficiency, warns a comprehensive new report by an international group of medical researchers.

23 Mar 2004

Stem cell research that could help diabetics

University of Florida adult stem cell experts have restored normal blood sugar levels in diabetic mice for three months by chemically coaxing bone marrow cells to produce insulin, a hormone normally made in the pancreas.

22 Mar 2004

Youth obesity provides food for thought

With heart disease developing among children from the age of 10 through poor diet and low activity, young Australians are part of what the World Health Organisation has already termed an "international epidemic of childhood obesity".

22 Mar 2004

New computer program accurately estimates chance of developing breast cancer

CANCER Research UK scientists have devised a user-friendly computer program, called the IBIS risk evaluator, which can give the most accurate estimate yet of a woman's chance of developing breast cancer.

22 Mar 2004

Research suggests protein released from lungs could initiate labour

A protein released from the lungs of a developing mouse fetus initiates a cascade of chemical events leading to the mother's initiation of labor, researchers at UT Southwestern Medical Center at Dallas have found.

22 Mar 2004

Researchers discover new form of the Rett syndrome protein

Adrian Bird and Skirmantas Kriaucionis of the University of Edinburgh have discovered a novel form of the protein MeCP2. This alternate form, coined MeCP2 alpha, differs from the original only in the first 19 amino acids. Interestingly, Adrian Bird, Director of the Welcome Trust Centre for Cell Biology at Edinburgh University, found that MeCP2 alpha, is ten times more prevalent not only in the brain but also in other tissues. These findings are currently reported online in Nucleic Acids Research. Similar findings were reported yesterday in Nature Genetics online by Berge Minassian, a neurologist and scientist at Toronto's Hospital for Sick Children.

22 Mar 2004

Clinical study - Diagnostic testing for epilepsy released

Bionomics Limited announced today the publication of its international clinical study involving patients with a form of epilepsy confined to early childhood in the scientific journal, Annals of Neurology. The publication details genes associated with a condition known as Benign Familial Neonatal Infantile Spasms (BFNIS), a condition in which infants experience seizures in the first few months of their life.

22 Mar 2004

Plasticiser Phthalates connected with rising infertility rates

Phthalates, largely used as plasticisers, have long been suspected in connection with rising infertility rates, particularly among men. These substances are quite common and are considered highly hazardous to human health because they disrupt the hormonal balance and impair reproduction and development. What has not been clear up to now is the amount of phthalates that enter the human body.

22 Mar 2004

New Treatment for Chronic Head Pain

Dr. Levy pioneered a procedure known as supraorbital nerve stimulation or SOS, in which neurotransmitters are implanted into the forehead to block head pain. Tiny wires are burrowed under the skin until the precise location of pain is marked by a tingling response to electrical charge. The wires are kept in place for a week, and if pain is lessened and the patient is comfortable with the technology, neurotransmitters are surgically implanted under local anesthesia. The patient is able to control pain relief by manually adjusting the level of electrical stimulation through a hand held device.

22 Mar 2004

Spina bifida on the decline

The incidence of spina bifida has decreased by 32 percent in the United States over the past decade. The decrease indicates the success of the Public Health Service’s recommendations released in 1992 urging women to increase their levels of folic acid intake prior to becoming pregnant.

22 Mar 2004

FDA approves new chewable formulation of Zyrtec® aimed at young allergy sufferers

Pfizer Inc and UCB Pharma today announced the approval of a new chewable formulation of Zyrtec® (cetirizine HCl) for the treatment of seasonal and perennial allergic rhinitis (inflammation of the nasal passages) and chronic idiopathic urticaria (itching and hives of unknown causes) in children aged two years and older. The approval by the US Food and Drug Administration makes Zyrtec the first and only prescription antihistamine available in both syrup and chewable form.

22 Mar 2004

Research suggest tea total only way to go when pregnant

The cardinal rule of a safe pregnancy is to avoid heavy drinking. However, new research indicates that even light to moderate drinking should be avoided as it may interfere with learning and memory in children as late as adolescence.

22 Mar 2004

Study of three treatments of type 2 diabetes in children and teens has begun in US

A clinical study comparing three treatments of type 2 diabetes in children and teens has begun in 12 medical centers and their affiliated sites around the country, HHS Secretary Tommy G. Thompson announced today.

22 Mar 2004

Japanese study raises concerns for childhood health issues

The number of children suffering from mental disorders and health problems such as allergies and asthma has risen sharply over the past decade in this country. The United States and European countries are also facing the increasingly serious problems of premature births and childhood obesity, in addition to allergic reactions. Many experts say the rise in health problems involving children is related to the use of chemicals in our daily lives and the impact of medical treatment provided to the children's mothers.

22 Mar 2004